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Targeting KIF11 Degradation: Oxypeucedanin Inhibits Lung Adenocarcinoma Progression by Disrupting the MCM2-CDK1 Signaling Pathway

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1. scibot 21 Jul 2026
  
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  AB_2072132
  
  DOI: 10.1016/j.phymed.2026.158611
  
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sciencedirect.com/science/article/pii/S0944711326008421
Jun 2026
www.nature.com www.nature.com

Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s41598-026-46639-y
  
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nature.com/articles/s41598-026-46639-y
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

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1. scibot 13 Jun 2026
  
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  DOI: 10.1002/2211-5463.70189
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13238917/
Feb 2026
54.241.53.176 54.241.53.176

2026.01.30.702807v1.full-html.html

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1. scibot 12 Feb 2026
  
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  RRID:AB_2072132
  
  DOI: 10.64898/2026.01.30.702807
  
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  DOI: 10.64898/2026.01.30.702807
  
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54.241.53.176/a1fb126143f6ebd2aa86840167c32224c61cfe36/2026.01.30.702807v1.full-html.html
Jan 2026
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Extracellular matrix stiffness drives post-mitotic nuclear pore complex assembly to promote neuroblastoma pathogenesis

1
1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116858
  
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sciencedirect.com/science/article/pii/S2211124725016304
Sep 2025
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A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.chembiol.2025.08.004
  
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sciencedirect.com/science/article/pii/S2451945625002557
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ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation

1
1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116230
  
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sciencedirect.com/science/article/pii/S2211124725010010
Jul 2025
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KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.011
  
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sciencedirect.com/science/article/pii/S1535610825002612
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Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer

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1. scibot 08 Jul 2025
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.xcrm.2025.102218
  
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sciencedirect.com/science/article/pii/S2666379125002915
Jan 2025
www.jidonline.org www.jidonline.org

5’-cap-dependent translation as a potent therapeutic target for lethal human squamous cell carcinoma

1
1. scibot 10 Jan 2025
  
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  Cyclin B1
  
  DOI: 10.1016/j.jid.2020.08.021
  
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jidonline.org/article/S0022-202X(20)32066-2/fulltext
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G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis

1
1. scibot 09 Jan 2025
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.celrep.2024.115178
  
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sciencedirect.com/science/article/pii/S2211124724015298
Nov 2024
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Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer

1
1. scibot 15 Nov 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.isci.2024.111283
  
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sciencedirect.com/science/article/pii/S2589004224025082
Sep 2024
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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival

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1. scibot 12 Sep 2024
  
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  AB_2072132
  
  DOI: 10.1016/j.cell.2024.08.020
  
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sciencedirect.com/science/article/pii/S0092867424009115
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers

1
1. scibot 21 Aug 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1126/science.adk0775
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
Jul 2024
www.cell.com www.cell.com

A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer

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1. scibot 25 Jul 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.chembiol.2024.06.012
  
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cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
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Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers

1
1. scibot 18 Jul 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1126/science.adk0775
  
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science.org/doi/10.1126/science.adk0775
May 2024
52.53.155.43 52.53.155.43

ol_28_1_14449_PDF-html.html

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1. scibot 17 May 2024
  
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  RRID:AB_2072132
  
  DOI: 10.3892/ol.2024.14449
  
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52.53.155.43/917364cd3fceb398a38ff7cf2bbe2411971526ce/ol_28_1_14449_PDF-html.html
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis

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1. scibot 28 Mar 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.isci.2024.109288
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

1
1. scibot 19 Mar 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cell.2024.02.023
  
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sciencedirect.com/science/article/pii/S0092867424002253
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Securin acetylation prevents precocious separase activation and premature sister chromatid separation

4
1. scibot 06 Mar 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cub.2024.02.038
  
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2. scibot 06 Mar 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cub.2024.02.038
  
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3. scibot 06 Mar 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cub.2024.02.038
  
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4. scibot 06 Mar 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cub.2024.02.038
  
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sciencedirect.com/science/article/pii/S0960982224001805
Feb 2024
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Sphingolipid metabolism controls mammalian heart regeneration

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1. scibot 21 Feb 2024
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cmet.2024.01.017
  
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sciencedirect.com/science/article/pii/S1550413124000172
Dec 2023
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Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation

1
1. scibot 06 Dec 2023
  
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  Cyclin B1
  
  DOI: 10.1016/j.cub.2021.01.062
  
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sciencedirect.com/science/article/pii/S0960982221001275
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer

1
1. scibot 31 Oct 2023
  
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  AB_2072132
  
  DOI: 10.3390/cancers15205082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10605716/
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Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5

1
1. scibot 01 Oct 2023
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.celrep.2023.113145
  
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sciencedirect.com/science/article/pii/S2211124723011579
Feb 2023
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An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation

1
1. scibot 02 Feb 2023
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.chembiol.2023.01.003
  
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sciencedirect.com/science/article/pii/S2451945623000260
Sep 2022
www.nature.com www.nature.com

A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice

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1. scibot 10 Sep 2022
  
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  RRID:AB_2072132
  
  DOI: 10.1038/s42003-022-03917-5
  
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nature.com/articles/s42003-022-03917-5
Jul 2022
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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

1
1. scibot 15 Jul 2022
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.cmet.2022.06.010
  
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sciencedirect.com/science/article/pii/S1550413122002303
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes

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1. scibot 16 Feb 2022
  
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  RRID:AB_2072132
  
  DOI: 10.1158/0008-5472.CAN-20-4190
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8373815/
Aug 2021
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Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition

1
1. scibot 15 Aug 2021
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.devcel.2021.06.019
  
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sciencedirect.com/science/article/pii/S1534580721005268
Jun 2021
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The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair

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1. scibot 30 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109306
  
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sciencedirect.com/science/article/pii/S2211124721006823
May 2021
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LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through MEK/ERK signaling pathway

1
1. scibot 11 May 2021
  
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  AB_2072132
  
  DOI: 10.1016/j.molmet.2021.101230
  
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sciencedirect.com/science/article/pii/S2212877821000752
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Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability

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1. scibot 05 May 2021
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.devcel.2020.11.012
  
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sciencedirect.com/science/article/pii/S1534580720308881
Mar 2021
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MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

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1. scibot 01 Mar 2021
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.ccell.2020.12.010
  
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sciencedirect.com/science/article/pii/S1535610820306589
Sep 2020
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Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases

1
1. scibot 26 Sep 2020
  
  in Public
  
  anti-cyclin B1
  
  DOI: 10.1016/j.celrep.2020.108181
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124720311700
elifesciences.org elifesciences.org

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

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1. scibot 17 Sep 2020
  
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  RRID:AB_2072132
  
  DOI: 10.7554/eLife.44161
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @evieth
  
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  RRID:AB_2072132 RRIDCUR:Validated
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elifesciences.org/articles/44161
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Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner

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1. scibot 04 Sep 2020
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.celrep.2020.107858
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_2072132
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sciencedirect.com/science/article/pii/S2211124720308391
Jan 2020
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GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway

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1. scibot 13 Jan 2020
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.yexcr.2019.111806
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @ethanbadger
  
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  RRID:AB_2072132 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0014482719306949
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.chembiol.2019.02.015
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @ethanbadger
  
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  RRID:AB_2072132 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619300704
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2072132
  
  DOI: 10.7554/eLife.44161
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6436895/
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_2072132
  
  DOI: 10.1016/j.celrep.2019.01.101
  
  Resource: (Cell Signaling Technology Cat# 4138, RRID:AB_2072132)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S221112471930138X
Nov 2018
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Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps

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1. scibot 05 Nov 2018
  
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  RRID:AB_2072132
  
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  (Cell Signaling Technology Cat# 4138S, RRID:AB_2072132)
  
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sciencedirect.com/science/article/pii/S1534580717308262
Nov 2017
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Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

1
1. scibot 08 Nov 2017
  
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  AB_2072132
  
  Curator: @kaitlinsung
  
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  (Cell Signaling Technology Cat# 4138S, RRID:AB_2072132)
  
  SciCrunch record: RRID:AB_2072132
  
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  RRID:AB_2072132 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413117300943