96 Matching Annotations
  1. Last 7 days
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    Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes
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    1. scibot 21 Dec 2024
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    sciencedirect.com/science/article/pii/S0092867424013473
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    Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsets
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    sciencedirect.com/science/article/pii/S2589004224024738
  4. Dec 2024
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    Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
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    sciencedirect.com/science/article/pii/S1535610824004483
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    A yeast-based oral therapeutic delivers immune checkpoint inhibitors to reduce intestinal tumor burden
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    sciencedirect.com/science/article/pii/S2451945624004525
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    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
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    1. scibot 02 Dec 2024
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    sciencedirect.com/science/article/pii/S2211124724013743
  8. Nov 2024
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a universal inactivated influenza B vaccine based on the mosaic hemagglutinin-approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC11570629/
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    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
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    A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice
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    sciencedirect.com/science/article/pii/S1931312824004037
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    Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy
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    1. scibot 07 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11513825/
  13. Oct 2024
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    Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis
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    sciencedirect.com/science/article/pii/S2211124724011367
  15. Sep 2024
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    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610824003179
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    The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis
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    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010416
  18. Aug 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Epithelial organoid supports resident memory CD8 T cell differentiation
    1
    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009719
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    Inherent preference for polyunsaturated fatty acids instigates ferroptosis of Treg cells that aggravates high-fat-diet-related colitis
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    sciencedirect.com/science/article/pii/S2211124724009860
  21. Jul 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ATP-exporting channel Pannexin 1 promotes CD8+ T cell effector and memory responses
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    1. scibot 26 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11263643/
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    SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration
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    sciencedirect.com/science/article/pii/S2211124724007873
  24. Jun 2024
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    Intranasal SARS-CoV-2 Omicron variant vaccines elicit humoral and cellular mucosal immunity in female mice
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    sciencedirect.com/science/article/pii/S2352396424002202
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    Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement
    1
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    sciencedirect.com/science/article/pii/S2666379124002829
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    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
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    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S1550413124001773
  28. May 2024
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
    1
    1. scibot 17 May 2024
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    sciencedirect.com/science/article/pii/S1535610824001351
  30. Apr 2024
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
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    sciencedirect.com/science/article/pii/S221112472400442X
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    Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
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      DOI: 10.1126/scisignal.adh0439

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    science.org/doi/10.1126/scisignal.adh0439
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    sciencedirect.com/science/article/pii/S0092867424003039
  34. Mar 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10499045/
  36. Feb 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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    sciencedirect.com/science/article/pii/S1550413123004126
  38. Jan 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities
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    ncbi.nlm.nih.gov/pmc/articles/PMC10518355/
  40. Dec 2023
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    Dietary environmental factors shape the immune defense against Cryptosporidium infection
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    sciencedirect.com/science/article/pii/S1931312823004584
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    Attenuation of allergen-specific immunotherapy for atopic dermatitis by ectopic colonization of Brevundimonas vesicularis in the intestine
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    1. scibot 20 Dec 2023
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    sciencedirect.com/science/article/pii/S2666379123005578
  43. Oct 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Intermittent fasting induced ketogenesis inhibits mouse epithelial ovarian cancer by promoting antitumor T cell response
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    sciencedirect.com/science/article/pii/S2589004223019168
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    ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia
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    sciencedirect.com/science/article/pii/S2211124723012184
  46. Aug 2023
  47. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
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    Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection
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    sciencedirect.com/science/article/pii/S1074761323003278
  49. Jul 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Comparison of DNA vaccines with AS03 as an adjuvant and an mRNA vaccine against SARS-CoV-2
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      DOI: 10.1016/j.isci.2023.107120

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    sciencedirect.com/science/article/pii/S2589004223011975
  51. May 2023
  52. www.sciencedirect.com www.sciencedirect.com
    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
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      DOI: 10.1016/j.immuni.2023.04.005

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    sciencedirect.com/science/article/pii/S1074761323001735
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    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
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      DOI: 10.1016/j.chom.2023.04.010

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    sciencedirect.com/science/article/abs/pii/S1931312823001610
  54. Feb 2023
  55. www.sciencedirect.com www.sciencedirect.com
    HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
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    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.isci.2023.106143

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    sciencedirect.com/science/article/pii/S2589004223002201
  56. Jan 2023
  57. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor
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      DOI: 10.1016/j.immuni.2022.12.002

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    sciencedirect.com/science/article/pii/S1074761322006069
  58. Nov 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  60. www.sciencedirect.com www.sciencedirect.com
    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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  61. Jul 2022
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    B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation
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  63. Jun 2022
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    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
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  65. May 2022
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    Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
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  67. Feb 2022
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    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
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  69. Jan 2022
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    Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
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  71. Dec 2021
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    Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
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  73. Nov 2021
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    Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria
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  77. Oct 2021
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  81. Aug 2021
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    Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease
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    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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    CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment
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  90. Jun 2021
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    DHX15 is required to control RNA virus-induced intestinal inflammation
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    Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function
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  93. Apr 2021
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    Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials
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    TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma
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    Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  99. Feb 2021
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    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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    An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses
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  103. Sep 2020
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    Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis
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    Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non–Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae
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    Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids
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    Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes
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    T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development
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  110. Jan 2020
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    Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
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    B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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    Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype
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    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations
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    Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production
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    Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
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    Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
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  128. Nov 2017
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    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
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    The ghrelin/GOAT system regulates obesity-induced inflammation in male mice.
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