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Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116993
  
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sciencedirect.com/science/article/pii/S2211124726000719
Feb 2026
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CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma

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1. scibot 13 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114840
  
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sciencedirect.com/science/article/pii/S2589004226002154
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression

1
1. scibot 30 Jan 2026
  
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  DOI: 10.7150/ijbs.123790
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12836506/
Sep 2025
52.53.155.43 52.53.155.43

1-s2.0-S0531556525002098-main-html.html

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.exger.2025.112880
  
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52.53.155.43/5584957b76ac485235fd64ade889b71206fc7ad5/1-s2.0-S0531556525002098-main-html.html
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Shenyuan granules improve cellular senescence through Klotho-mediated p16/p21 signaling pathway in diabetic kidney disease

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1. scibot 16 Aug 2025
  
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  DOI: 10.3389/fmed.2025.1627412
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12350460/
Feb 2025
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Designer polyQ fusion proteins sequester USP7/HDM2 for modulating P53 functionality

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1. scibot 28 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.112025
  
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sciencedirect.com/science/article/pii/S2589004225002858
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225001142-main-html.html

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1. scibot 23 Jan 2025
  
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  RRID:AB_207768
  
  DOI: 10.1016/j.isci.2025.111854
  
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52.53.155.43/4ba4d4aa1791368b1b3c245d42e19adb8410307c/1-s2.0-S2589004225001142-main-html.html
Sep 2024
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.026
  
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sciencedirect.com/science/article/pii/S1097276524007032
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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.013
  
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sciencedirect.com/science/article/pii/S0092867424009048
Aug 2024
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A single-cell transcriptomic census of mammalian olfactory epithelium aging

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.07.020
  
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sciencedirect.com/science/article/pii/S1534580724004829
Jul 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 18 Jul 2024
  
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  RRID:AB_2077682
  
  DOI: 10.1111/bph.16494
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16494
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4

1
1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110163
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11226984/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy

1
1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.ebiom.2024.105212
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11261775/
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Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110144
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
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METTL1-Modulated LSM14A Facilitates Proliferation and Migration in Glioblastoma via the Stabilization of DDX5

1
1. scibot 10 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110225
  
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sciencedirect.com/science/article/pii/S2589004224014500
Jun 2024
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The phosphorylation-deubiquitination positive feedback loop of the CHK2-USP7 axis stabilizes p53 under oxidative stress

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114366
  
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sciencedirect.com/science/article/pii/S2211124724006946
onlinelibrary.wiley.com onlinelibrary.wiley.com

14-3-3σ/Stratifin and p21 limit AKT-related malignant progression in skin carcinogenesis following MDM2-associated p53 loss

1
1. scibot 16 Jun 2024
  
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  RRID:AB_2077682
  
  DOI: 10.1002/mc.23771
  
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onlinelibrary.wiley.com/doi/10.1002/mc.23771
May 2024
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia

1
1. scibot 25 May 2024
  
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  AB_2077682
  
  DOI: 10.1113/JP285339
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP285339
Apr 2024
52.53.155.43 52.53.155.43

gaae015-html.html

1
1. scibot 19 Apr 2024
  
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  DOI: 10.1093/molehr/gaae015
  
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52.53.155.43/2937ae15ffb949fde49a3f9100cc82616d52fb7b/gaae015-html.html
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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

1
1. scibot 16 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114111
  
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sciencedirect.com/science/article/pii/S221112472400439X
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An integrated multi-omics analysis reveals osteokines involved in global regulation

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1. scibot 04 Apr 2024
  
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  DOI: 10.1016/j.cmet.2024.03.006
  
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  RRID:AB_2077682
  
  DOI: 10.1016/j.cmet.2024.03.006
  
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sciencedirect.com/science/article/pii/S1550413124000858
Feb 2024
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DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma

3
1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109181
  
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2. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109181
  
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3. scibot 29 Feb 2024
  
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  RRID:AB_2077682
  
  DOI: 10.1016/j.isci.2024.109181
  
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sciencedirect.com/science/article/pii/S2589004224004024
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Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

1
1. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113738
  
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sciencedirect.com/science/article/pii/S2211124724000664
Dec 2023
www.mdpi.com www.mdpi.com

The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian Insufficiency

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1. scibot 14 Dec 2023
  
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  DOI: 10.3390/ijms242417193
  
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mdpi.com/1422-0067/24/24/17193
Nov 2023
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Mechanical overloading leads to chondrocyte degeneration and senescence via Zmpste24 mediated nuclear membrane instability

2
1. scibot 04 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108119
  
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2. scibot 04 Nov 2023
  
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  RRID:AB_2077682
  
  DOI: 10.1016/j.isci.2023.108119
  
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sciencedirect.com/science/article/pii/S258900422302196X
Apr 2023
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CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue

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1. scibot 22 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112424
  
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sciencedirect.com/science/article/pii/S2211124723004357
www.cell.com www.cell.com

Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development

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1. scibot 13 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.03.016
  
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cell.com/developmental-cell/fulltext/S1534-5807(23)00132-6
Jan 2023
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 14 Jan 2023
  
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  DOI: 10.1111/bph.15997
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15997
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Paris polyphylla ethanol extract induces G2/M arrest and suppresses migration and invasion in bladder cancer

1
1. scibot 05 Feb 2022
  
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  RRID:AB_2077682
  
  DOI: 10.21037/tcr-20-1512
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8797771/
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8593568/
Jan 2020
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Three kinds of corneal host cells contribute differently to corneal neovascularization

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1. scibot 12 Jan 2020
  
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  RRID:AB_2077682
  
  DOI: 10.1016/j.ebiom.2019.05.026
  
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  Curator: @ethanbadger
  
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  RRID:AB_2077682 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2352396419303275