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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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  3. Dec 2024
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    Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells
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    CCDC134 controls TLR biogenesis through the ER chaperone Gp96
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  6. Nov 2024
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    Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation
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  8. Oct 2024
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    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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    Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon
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  11. Aug 2024
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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  13. Jul 2024
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    pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism
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  15. Jun 2024
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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  17. May 2024
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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  19. Mar 2024
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    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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  21. Feb 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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  26. Jan 2024
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    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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  29. Nov 2023
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    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
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  33. Oct 2023
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    LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway
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    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
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    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
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  37. 52.53.155.43 52.53.155.43
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    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
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  39. Sep 2023
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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  41. Aug 2023
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    Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome
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    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
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  45. Jul 2023
  46. 52.53.155.43 52.53.155.43
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  47. Jun 2023
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    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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    Sublethal necroptosis signaling promotes inflammation and liver cancer
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  50. May 2023
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    VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
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    sciencedirect.com/science/article/pii/S2211124723005004
  52. Apr 2023
  53. link.springer.com link.springer.com
    N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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  55. Feb 2023
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    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease
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  58. Jan 2023
  59. www.sciencedirect.com www.sciencedirect.com
    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
    1
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      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2022.111961

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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
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      RRID:AB_2079382

      DOI: 10.1016/j.isci.2022.105769

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  61. Oct 2022
  62. www.sciencedirect.com www.sciencedirect.com
    The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling
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      RRID:AB_2079382

      DOI: 10.1016/j.isci.2022.105066

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  63. Sep 2022
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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      AB_2079382

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  65. Apr 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB
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  67. Mar 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
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      2697

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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis
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  70. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.335163

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  71. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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      Cell Signaling Tehnology cat# 2697

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  72. Jan 2022
  73. www.sciencedirect.com www.sciencedirect.com
    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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      2697

      DOI: 10.1016/j.biopha.2022.112615

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  74. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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      DOI: 10.1016/j.molcel.2021.12.006

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  75. Dec 2021
  76. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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      DOI: 10.1038/s41467-021-27452-9

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  77. Oct 2021
  78. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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      RRID:AB_2079382

      DOI: 10.15252/embr.202052254

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  79. Aug 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
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      RRID:AB_2079382

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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      DOI: 10.1523/JNEUROSCI.2238-14.2014

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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1210/en.2017-00495

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  83. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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      RRID:AB_2079382

      DOI: 10.1016/j.cell.2018.09.011

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  84. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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      RRID:AB_2079382

      DOI: 10.1016/j.cell.2018.07.041

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    Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease
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      RRID:AB_2079382

      DOI: 10.1016/j.immuni.2021.07.004

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  86. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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      RRID:AB_2079382

      DOI: 10.1016/j.chom.2018.11.001

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2079382

      DOI: 10.7554/eLife.24425

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  88. Jul 2021
  89. www.sciencedirect.com www.sciencedirect.com
    Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
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      Rabbit monoclonal anti-p-IKKα/β

      DOI: 10.1016/j.celrep.2019.11.014

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF‐κB signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC6344303/
  91. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
    1
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      RRID: AB_2079382

      DOI: 10.1016/j.cell.2018.09.011

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  92. www.jneurosci.org www.jneurosci.org
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      RRID:AB_2079382

      DOI: 10.1523/JNEUROSCI.2238-14.2014

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    jneurosci.org/content/34/37/12490
  93. www.sciencedirect.com www.sciencedirect.com
    A constitutively-active IKK-complex at the axon initial segment
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    1. scibot 27 Jul 2021
      RRID:AB_10120863

      DOI: 10.1016/j.brainres.2017.10.020

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  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Palmitate‐induced C/EBP homologous protein activation leads to NF‐κB‐mediated increase in BACE1 activity and amyloid beta genesis
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      AB_2291699

      DOI: 10.1111/jnc.14292

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  95. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2021.109364

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  96. Jun 2021
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
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      RRID:AB_2079382

      DOI: 10.7554/eLife.67315

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    ncbi.nlm.nih.gov/pmc/articles/PMC8192125/
  98. May 2021
  99. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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      RRID:AB_2079382

      DOI: 10.1016/j.immuni.2021.04.027

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  100. www.sciencedirect.com www.sciencedirect.com
    N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation
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      RRID:AB_2079382

      DOI: 10.1016/j.devcel.2020.10.023

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  101. Mar 2021
  102. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_2079382

      DOI: 10.1111/bph.15396

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15396
  103. Nov 2020
  104. www.frontiersin.org www.frontiersin.org
    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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      AB_2079382

      DOI: 10.3389/fimmu.2020.559332

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    frontiersin.org/article/10.3389/fimmu.2020.559332/full
  105. Sep 2020
  106. www.sciencedirect.com www.sciencedirect.com
    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
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      RRID:AB_2079382

      DOI: 10.1016/j.bcp.2020.113949

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  107. www.sciencedirect.com www.sciencedirect.com
    BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells
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      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2020.03.038

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  108. www.sciencedirect.com www.sciencedirect.com
    The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis
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      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2019.12.051

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  109. www.sciencedirect.com www.sciencedirect.com
    Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation
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      RRID:AB_2079382

      DOI: 10.1016/j.molcel.2020.01.022

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  110. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2020.03.056

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  111. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2020.03.029

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  112. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_2079382

      DOI: 10.1111/bph.15182

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
  113. academic.oup.com academic.oup.com
    Gut hormone GIP induces inflammation and insulin resistance in the hypothalamus
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    1. scibot 06 Sep 2020
      RRID:AB_2079382

      DOI: 10.1210/endocr/bqaa102

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    academic.oup.com/endo/article/161/9/bqaa102/5865317
  114. Aug 2020
  115. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis
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    1. scibot 27 Aug 2020
      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2020.02.062

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720302308
  116. Jan 2020
  117. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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    1. scibot 13 Jan 2020
      RRID:AB_2079382

      DOI: 10.1016/j.immuni.2019.01.007

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    sciencedirect.com/science/article/pii/S1074761319300305
  118. www.sciencedirect.com www.sciencedirect.com
    MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity
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    1. scibot 13 Jan 2020
      RRID:AB_2079382

      DOI: 10.1016/j.molcel.2019.01.022

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    sciencedirect.com/science/article/pii/S1097276519300425
  119. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2079382

      DOI: 10.1016/j.celrep.2019.03.028

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    sciencedirect.com/science/article/pii/S2211124719303444
  120. Nov 2018
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      AB_2079382

      Curator: @evieth

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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27360
  122. www.sciencedirect.com www.sciencedirect.com
    LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling
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      2697

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    sciencedirect.com/science/article/pii/S1097276518306488
  123. link.springer.com link.springer.com
    Curcumin Attenuates gp120-Induced Microglial Inflammation by Inhibiting Autophagy via the PI3K Pathway
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      Curator: @evieth

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    link.springer.com/article/10.1007/s10571-018-0616-3
  124. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418309693
  125. www.sciencedirect.com www.sciencedirect.com
    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
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    sciencedirect.com/science/article/pii/S1934590918302844
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway
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      Curator: @anp055

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    onlinelibrary.wiley.com/doi/full/10.1111/acel.12774
  127. academic.oup.com academic.oup.com
    IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase
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      AB_2079382

      Curator: @evieth

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    academic.oup.com/endo/article/158/12/4270/4117214
  128. Nov 2017
  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14131/full
  130. elifesciences.org elifesciences.org
    Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
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    1. scibot 08 Nov 2017
      AB_2079382

      Curator: @chewbeccax

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    elifesciences.org/articles/24425
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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      AB_2079382

      Curator: @gabimpine

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