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Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer

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1. scibot 02 Dec 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1038/s41388-025-03343-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12127007/
Nov 2025
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WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair

1
1. scibot 05 Nov 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.celrep.2025.116520
  
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sciencedirect.com/science/article/pii/S2211124725012914
Oct 2025
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Targeting the ERα DBD-LBD interface with mitoxantrone disrupts receptor function through proteasomal degradation

1
1. scibot 08 Oct 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1158/1535-7163.MCT-25-0405
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12496009/
54.241.53.176 54.241.53.176

2025.09.25.678487v1.full-html.html

1
1. scibot 07 Oct 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1101/2025.09.25.678487
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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54.241.53.176/6242d0964f3f11ac8334753a1121987506367c6b/2025.09.25.678487v1.full-html.html
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RECLASSIFICATION OF ATM MISSENSE VARIANTS OF UNCERTAIN SIGNIFICANCE BY INTEGRATING RESULTS FROM SYSTEMATIC FUNCTIONAL ASSAYS INTO AN ACMG POINTS-BASED FRAMEWORK

1
1. scibot 10 Jul 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1158/1078-0432.CCR-24-3936
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12234152/
Apr 2025
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Halting hepatocellular carcinoma: Identifying intercellular crosstalk in HBV-driven disease

1
1. scibot 01 Apr 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.celrep.2025.115457
  
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sciencedirect.com/science/article/pii/S2211124725002281
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 24 Mar 2025
  
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  RRID:AB_2080793
  
  DOI: 10.1158/1078-0432.ccr-24-3936
  
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52.53.155.43/9d2d72079ea8ca48f04203f494da6924c0f290ae/PDF-html.html
Sep 2024
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

1
1. scibot 25 Sep 2024
  
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  RRID:AB_590521
  
  DOI: 10.1016/j.molcel.2019.06.043
  
  Resource: (MBL International Cat# LS-A2662, RRID:AB_590521)
  
  Curator: @ethanbadger
  
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  RRID:AB_590521 RRID:AB_2080793 RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S1097276519305003
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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival

1
1. scibot 12 Sep 2024
  
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  AB_2080793
  
  DOI: 10.1016/j.cell.2024.08.020
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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sciencedirect.com/science/article/pii/S0092867424009115
Jun 2024
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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

1
1. scibot 04 Jun 2024
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.devcel.2024.05.010
  
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sciencedirect.com/science/article/pii/S1534580724003277
Oct 2023
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Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells

1
1. scibot 14 Oct 2023
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.celrep.2023.113180
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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sciencedirect.com/science/article/pii/S2211124723011920
Sep 2023
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The interplay of TARG1 and PARG protects against genomic instability

1
1. scibot 12 Sep 2023
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.celrep.2023.113113
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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sciencedirect.com/science/article/pii/S2211124723011245
Jul 2023
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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling

1
1. scibot 14 Jul 2023
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.ccell.2023.06.007
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1535610823002179
Apr 2023
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A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer

1
1. scibot 19 Apr 2023
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.xcrm.2023.101015
  
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sciencedirect.com/science/article/pii/S2666379123001258
Aug 2022
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Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop

1
1. scibot 30 Aug 2022
  
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  AB_2080793
  
  DOI: 10.1016/j.isci.2022.104944
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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sciencedirect.com/science/article/pii/S2589004222012160
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress

1
1. scibot 05 Apr 2022
  
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  RRID:AB_2080793
  
  DOI: 10.1038/s41598-022-09308-4
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8971416/
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer

1
1. scibot 22 Jan 2022
  
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  RRID:AB_2080793
  
  DOI: 10.3390/cancers14020326
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8773906/
Dec 2021
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

1
1. scibot 09 Dec 2021
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.celrep.2021.110080
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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sciencedirect.com/science/article/pii/S2211124721015710
Jun 2021
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MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

1
1. scibot 23 Jun 2021
  
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  AB_2080793
  
  DOI: 10.1016/j.ebiom.2021.103441
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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sciencedirect.com/science/article/pii/S2352396421002346
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

1
1. scibot 16 Jun 2021
  
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  AB_2080793
  
  DOI: 10.3390/cancers13112840
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
Mar 2021
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TRPS1 drives heterochromatic origin refiring and cancer genome evolution

1
1. scibot 10 Mar 2021
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.celrep.2021.108814
  
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sciencedirect.com/science/article/pii/S2211124721001285
Jan 2020
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Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.stem.2019.06.011
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
  Curator: @ethanbadger
  
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  RRID:AB_2080793 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590919302759
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2080793
  
  DOI: 10.1016/j.molcel.2019.02.014
  
  Resource: (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
  Curator: @ethanbadger
  
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  RRID:AB_2080793 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519301042
Nov 2018
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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation

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1. scibot 05 Nov 2018
  
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  RRID:AB_2080793
  
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sciencedirect.com/science/article/pii/S1535610818302691
Nov 2017
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Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

1
1. scibot 08 Nov 2017
  
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  AB_2080793
  
  Curator: @kaitlinsung
  
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  (Cell Signaling Technology Cat# 2662, RRID:AB_2080793)
  
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  RRID:AB_2080793 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413117300943