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Jun 2026
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The heat shock transcription factor, HSF1, stimulates the catalytic engagement of topoisomerase IIβ over topoisomerase IIα

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1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.molcel.2026.05.014
  
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sciencedirect.com/science/article/pii/S1097276526003205
May 2026
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Transcription and cohesin direct domain boundary spatial positioning and are linked to Friedreich’s ataxia

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Mar 2026
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A developmentally regulated long-range enhancer-promoter contact mediates human neural development

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pmc.ncbi.nlm.nih.gov/articles/PMC12822576/
Jan 2026
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CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells

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Dec 2025
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Notch interaction with RUNX factors regulates initiation of the T-lineage program

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  DOI: 10.1084/jem.20250911
  
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rupress.org/jem/article/223/2/e20250911/278551/Notch-interaction-with-RUNX-factors-regulates
Nov 2025
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Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12050968/
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Mapping of chromatin architecture and enhancer-promoter interactions in the cochlea

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  DOI: 10.3389/fmolb.2025.1683964
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12568336/
Jun 2025
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Regulation of epigenetics and chromosome structure by human ORC2

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  DOI: 10.1016/j.celrep.2025.115816
  
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sciencedirect.com/science/article/pii/S221112472500587X
Apr 2025
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Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis

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Halting hepatocellular carcinoma: Identifying intercellular crosstalk in HBV-driven disease

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sciencedirect.com/science/article/pii/S2211124725002281
Mar 2025
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Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma

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Binding domain mutations provide insight into CTCF’s relationship with chromatin and its contribution to gene regulation

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  DOI: 10.1016/j.xgen.2025.100813
  
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cell.com/cell-genomics/fulltext/S2666-979X(25)00069-2
Feb 2025
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Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer

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  DOI: 10.1016/j.celrep.2025.115267
  
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sciencedirect.com/science/article/pii/S2211124725000385
Jan 2025
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Co-essentiality analysis identifies PRR12 as a cohesin interacting protein and contributor to genomic integrity

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  DOI: 10.1016/j.devcel.2024.12.015
  
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sciencedirect.com/science/article/pii/S1534580724007378
Dec 2024
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Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models

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1. scibot 28 Dec 2024
  
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  DOI: 10.1101/2024.12.03.626438
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11642846/
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ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF

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  DOI: 10.1016/j.molcel.2024.11.031
  
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sciencedirect.com/science/article/pii/S1097276524009560
Jun 2024
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Hypoxia-induced CTCF promotes EMT in breast cancer

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114367
  
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sciencedirect.com/science/article/pii/S2211124724006958
May 2024
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Deciphering the TET3 interactome in primary thymic developing T cells

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1. scibot 09 May 2024
  
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  DOI: 10.1016/j.isci.2024.109782
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11070343/
Feb 2024
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Mapping catalytically engaged TOP2B in neurons reveals the principles of topoisomerase action within the genome

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sciencedirect.com/science/article/pii/S2211124724001372
Dec 2023
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Epigenetic priming of an epithelial enhancer by p63 and CTCF controls expression of a skin-restricted gene XP33

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1. scibot 13 Dec 2023
  
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  DOI: 10.1038/s41420-023-01716-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10709559/
Oct 2023
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Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement

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  DOI: 10.1016/j.cell.2023.09.009
  
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sciencedirect.com/science/article/pii/S0092867423010280
Aug 2023
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G-quadruplexes associated with R-loops promote CTCF binding

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Jul 2023
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Modeling epigenetic lesions that cause gliomas

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  DOI: 10.1016/j.cell.2023.06.022
  
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Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies

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  DOI: 10.1016/j.isci.2023.107128
  
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sciencedirect.com/science/article/pii/S2589004223012051
Jun 2023
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Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus

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  DOI: 10.1016/j.celrep.2023.112569
  
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May 2023
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Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer

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Apr 2023
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Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia

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Sep 2022
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Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development

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Aug 2022
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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression

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May 2022
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Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome

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Apr 2022
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Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma

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Feb 2022
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Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility

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  DOI: 10.1016/j.neuron.2021.12.034
  
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sciencedirect.com/science/article/pii/S0896627321010898
Jan 2022
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SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers

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1. scibot 26 Jan 2022
  
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  DOI: 10.1016/j.molcel.2021.12.037
  
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sciencedirect.com/science/article/pii/S1097276521011424
Nov 2021
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Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells

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  DOI: 10.1016/j.celrep.2021.109909
  
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Aug 2021
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Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.ccell.2018.11.002
  
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Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes

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Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes

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Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

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Cell-specific exon methylation and CTCF binding in neurons regulate calcium ion channel splicing and function

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Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP

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Jan 2020
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Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications

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R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation

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Untitled document

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Nov 2018
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Polymer Simulations of Heteromorphic Chromatin Predict the 3D Folding of Complex Genomic Loci

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Cohesin Loss Eliminates All Loop Domains

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Multiscale 3D Genome Rewiring during Mouse Neural Development

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