108 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFRD1 is required for maintenance of bladder epithelial homeostasis
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    1. scibot 13 Dec 2024
      RRID:AB_2089254

      DOI: 10.1016/j.isci.2024.111282

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    pmc.ncbi.nlm.nih.gov/articles/PMC11613175/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
    1
    1. scibot 12 Dec 2024
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      DOI: 10.1158/0008-5472.CAN-24-1102

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  4. www.sciencedirect.com www.sciencedirect.com
    Endoplasmic reticulum stress-related deficits in calcium clearance promote neuronal dysfunction that is prevented by SERCA2 gene augmentation
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.xcrm.2024.101839

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    sciencedirect.com/science/article/pii/S2666379124006104
  5. Aug 2024
  6. www.authorea.com www.authorea.com
    Preliminary exploration of endoplasmic reticulum stress transmission in astrocytes and neurons, and its mediators
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    1. scibot 18 Aug 2024
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      DOI: 10.22541/au.172258066.64851176/v1

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    authorea.com/users/811586/articles/1213019-preliminary-exploration-of-endoplasmic-reticulum-stress-transmission-in-astrocytes-and-neurons-and-its-mediators
  7. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
    1
    1. scibot 02 Aug 2024
      2895

      DOI: 10.1186/s13578-021-00640-2

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    cellandbioscience.biomedcentral.com/article/10.1186/s13578-021-00640-2
  8. www.mdpi.com www.mdpi.com
    Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent Mice
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    1. scibot 02 Aug 2024
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      DOI: 10.3390/cells10050996

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    mdpi.com/2073-4409/10/5/996/htm
  9. Jul 2024
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
    1
    1. scibot 23 Jul 2024
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      DOI: 10.1111/acel.14258

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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
  11. link.springer.com link.springer.com
    Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model
    1
    1. scibot 09 Jul 2024
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      DOI: 10.1007/s10735-024-10192-7

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    link.springer.com/article/10.1007/s10735-024-10192-7
  12. May 2024
  13. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
    1
    1. scibot 23 May 2024
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      DOI: 10.1158/1541-7786.MCR-23-0445

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    aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
  14. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
    1
    1. scibot 08 May 2024
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    sciencedirect.com/science/article/pii/S1550413124001347
  15. Apr 2024
  16. www.sciencedirect.com www.sciencedirect.com
    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114156

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    sciencedirect.com/science/article/pii/S2211124724004844
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
    1
    1. scibot 28 Apr 2024
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      DOI: 10.1016/j.isci.2024.109672

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039351/
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Caffeic acid does not protect human pancreatic β cells against stearic acid-induced ER stress and apoptosis
    1
    1. scibot 25 Apr 2024
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      DOI: 10.1002/ejlt.202300206

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    onlinelibrary.wiley.com/doi/full/10.1002/ejlt.202300206
  19. www.sciencedirect.com www.sciencedirect.com
    The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection
    1
    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.bbadis.2024.167193

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    sciencedirect.com/science/article/pii/S0925443924001820
  20. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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    1. scibot 19 Apr 2024
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      DOI: 10.1158/1541-7786.MCR-23-0676

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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
    1
    1. scibot 10 Apr 2024
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      DOI: 10.1038/s41593-024-01615-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11088998/
  22. Mar 2024
  23. www.sciencedirect.com www.sciencedirect.com
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
    1
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.bbadis.2024.167131

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    sciencedirect.com/science/article/pii/S0925443924001200
  24. www.sciencedirect.com www.sciencedirect.com
    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
    2
    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113900

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    sciencedirect.com/science/article/pii/S2211124724002286
  25. Feb 2024
  26. 52.53.155.43 52.53.155.43
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
    2
    1. scibot 29 Feb 2024
      AB_2089254

      DOI: 10.1101/2023.10.24.563545

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    2. scibot 29 Feb 2024
      AB_2089254

      DOI: 10.1101/2023.10.24.563545

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    52.53.155.43/208912a7429960b4182882fc2fcf60d73a185bc4/delete-html.html
  27. www.sciencedirect.com www.sciencedirect.com
    Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons?
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    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.ecoenv.2024.116104

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    2. scibot 21 Feb 2024
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      DOI: 10.1016/j.ecoenv.2024.116104

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    sciencedirect.com/science/article/pii/S0147651324001799
  28. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.isci.2024.109100

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    52.53.155.43/d3d22b34dc913e3c2adad8dc51a7839208721c99/PIIS2589004224003213-html.html
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
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    1. scibot 14 Dec 2023
      RRID:AB_2089524

      DOI: 10.1016/j.molmet.2023.101851

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    sciencedirect.com/science/article/pii/S2212877823001850
  31. Sep 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
    1
    1. scibot 17 Sep 2023
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      DOI: 10.1016/j.isci.2023.107731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10494175/
  33. Aug 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.isci.2023.107408

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  35. Jul 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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    1. scibot 12 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112746

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    sciencedirect.com/science/article/pii/S221112472300757X
  37. www.sciencedirect.com www.sciencedirect.com
    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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    1. scibot 05 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112700

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    sciencedirect.com/science/article/pii/S2211124723007118
  38. Jun 2023
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 30 Jun 2023
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      DOI: 10.1111/bph.16074

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16074
  40. May 2023
  41. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
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      DOI: 10.1210/endocr/bqad035

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    academic.oup.com/endo/article/164/4/bqad035/7056674
  42. www.sciencedirect.com www.sciencedirect.com
    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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    1. scibot 05 May 2023
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      DOI: 10.1016/j.celrep.2022.111092

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    sciencedirect.com/science/article/pii/S2211124722008944
  43. www.sciencedirect.com www.sciencedirect.com
    Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
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      DOI: 10.1016/j.chembiol.2022.06.010

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    sciencedirect.com/science/article/pii/S2451945622002422
  44. Apr 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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      DOI: 10.1016/j.cmet.2023.04.003

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    sciencedirect.com/science/article/pii/S1550413123001304
  46. www.sciencedirect.com www.sciencedirect.com
    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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      DOI: 10.1016/j.celrep.2023.112286

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    sciencedirect.com/science/article/pii/S2211124723002978
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  48. Mar 2023
  49. journals.lww.com journals.lww.com
    TUG-891 inhibits neuronal endoplasmic reticulum stress and... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.369116

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    journals.lww.com/nrronline/Fulltext/2023/10000/TUG_891_inhibits_neuronal_endoplasmic_reticulum.34.aspx
  50. 52.53.155.43 52.53.155.43
    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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    1. scibot 16 Mar 2023
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      DOI: 10.1101/2023.01.31.526464

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    52.53.155.43/56dd9657520d89efd227b99f30a1871711d5fdb7/2023.01.31.526464v1.full-html.html
  51. Feb 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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      DOI: 10.1016/j.isci.2023.106169

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    sciencedirect.com/science/article/pii/S2589004223002468
  53. www.mdpi.com www.mdpi.com
    Selenium Protects Mouse Hypothalamic Cells from Glucocorticoid-Induced Endoplasmic Reticulum Stress Vulnerability and Insulin Signaling Impairment
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      DOI: 10.3390/antiox12020526

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  54. Jan 2023
  55. journals.lww.com journals.lww.com
    Valproate reduces retinal ganglion cell apoptosis in rats... : Neural Regeneration Research
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    Oxygen-carrying sequential preservation mitigates liver grafts ischemia-reperfusion injury
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  57. Nov 2022
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    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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  59. Sep 2022
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    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
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    OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy
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    IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response
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  64. Jul 2022
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment
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    Small molecule-mediated insulin hypersecretion induces transient ER stress response and loss of beta cell function
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  68. Apr 2022
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress
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  70. Mar 2022
  71. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
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    Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  75. Feb 2022
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    The endoplasmic reticulum stress-mediated unfolded protein response protects against infection of goat endometrial epithelial cells by Trueperella pyogenes via autophagy
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  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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  78. Jan 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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    Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection
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    The portrait of liver cancer is shaped by mitochondrial genetics
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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  84. Dec 2021
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    β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation
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  86. Nov 2021
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    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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    ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
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  89. Oct 2021
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    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
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  92. Aug 2021
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    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
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  96. Jul 2021
  97. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells
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    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
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    Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides
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  101. May 2021
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    Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells
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    Pridopidine reduces mutant huntingtin-induced endoplasmic reticulum stress by modulation of the Sigma-1 receptor
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    Presynaptic store-operated Ca2+ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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  106. Apr 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism
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    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
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  109. www.sciencedirect.com www.sciencedirect.com
    Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output
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  110. Feb 2021
  111. elifesciences.org elifesciences.org
    Stem cell transplantation rescued a primary open-angle glaucoma mouse model
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  112. Dec 2020
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CB1R regulates soluble leptin receptor levels via CHOP, contributing to hepatic leptin resistance
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  114. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel HDAC6 inhibitor improves myelination of Schwann cells in a model of Charcot‐Marie‐Tooth disease type 1A
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  115. Sep 2020
  116. www.sciencedirect.com www.sciencedirect.com
    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
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  117. www.sciencedirect.com www.sciencedirect.com
    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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  118. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex
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  119. www.sciencedirect.com www.sciencedirect.com
    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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  120. www.nature.com www.nature.com
    GCAP neuronal calcium sensor proteins mediate photoreceptor cell death in the rd3 mouse model of LCA12 congenital blindness by involving endoplasmic reticulum stress
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  121. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.
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  122. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  123. Jan 2020
  124. www.sciencedirect.com www.sciencedirect.com
    The N-Degron Pathway Mediates ER-phagy
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  125. www.sciencedirect.com www.sciencedirect.com
    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
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  126. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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  127. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  128. www.sciencedirect.com www.sciencedirect.com
    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
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  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Profile of the Unfolded Protein Response in Rat Cerebellar Cortical Development
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      DOI: 10.1002/cne.24718

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  130. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2018.12.005

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  131. www.sciencedirect.com www.sciencedirect.com
    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      DOI: 10.1016/j.ccell.2019.01.006

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  133. Nov 2018
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFAP2 transcription factors are regulators of lipid droplet biogenesis
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  135. www.sciencedirect.com www.sciencedirect.com
    Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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  137. www.sciencedirect.com www.sciencedirect.com
    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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  139. link.springer.com link.springer.com
    Cannabinoid Receptor Type 1 Agonist ACEA Protects Neurons from Death and Attenuates Endoplasmic Reticulum Stress-Related Apoptotic Pathway Signaling
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  140. Nov 2017
  141. academic.oup.com academic.oup.com
    Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response
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