94 Matching Annotations
  1. Feb 2026
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    Generation of two tetracycline-inducible NGN2 iN iPSC lines carrying a heterozygous floating-Harbor syndrome SRCAP truncating mutation
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    sciencedirect.com/science/article/pii/S1873506126000188
  3. Oct 2025
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    Hide-and-Seek genome editing reveals that Gephyrin is required for axo-axonic synapse assembly
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    pnas.org/doi/abs/10.1073/pnas.2500726122
  5. Sep 2025
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    Altered NPTX2 dynamics associated with impaired cognitive aging
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    biorxiv.org/content/10.1101/2025.09.15.676156v1
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    Synaptic pruning following NMDAR-dependent LTD preferentially affects isolated synapses
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    sciencedirect.com/science/article/pii/S2589004225013549
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    ATM deficiency drives phenotypic diversity and Purkinje cell degeneration in a macaque model of ataxia-telangiectasia
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    sciencedirect.com/science/article/pii/S2666379125004288
  9. Aug 2025
  10. elifesciences.org elifesciences.org
    Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
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    elifesciences.org/articles/97100
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel roles for the GPI-anchor cleaving enzyme, GDE2, in hippocampal synaptic morphology and function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12320762/
  12. Jun 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CXCL12 engages cortical inhibitory neurons to enhance dendritic spine plasticity and structured network activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160403/
  14. May 2025
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    A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation
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    sciencedirect.com/science/article/pii/S1534580725002631
  16. Mar 2025
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  18. Apr 2024
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    Generation of human cerebral organoids with a structured outer subventricular zone
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    sciencedirect.com/science/article/pii/S2211124724003590
  20. Mar 2024
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B–/– mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11412912/
  22. elifesciences.org elifesciences.org
    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
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    elifesciences.org/articles/89453
  23. Jan 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication
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    ncbi.nlm.nih.gov/pmc/articles/PMC10976296/
  25. www.jneurosci.org www.jneurosci.org
    βII-Spectrin Is Required for Synaptic Positioning during Retinal Development
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    jneurosci.org/content/43/29/5277
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    Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10828548/
  28. Nov 2023
  29. www.sciencedirect.com www.sciencedirect.com
    The proteomic landscape of synaptic diversity across brain regions and cell types
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    sciencedirect.com/science/article/pii/S0092867423010826
  30. Aug 2023
  31. 52.53.155.43 52.53.155.43
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    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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    sciencedirect.com/science/article/pii/S1534580723003581
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    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0896627323005135
  34. Jul 2023
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    The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
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    sciencedirect.com/science/article/pii/S2211124723007544
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    Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors
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    Organelle mapping in dendrites of human iPSC-derived neurons reveals dynamic functional dendritic Golgi structures
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  38. May 2023
  39. www.biorxiv.org www.biorxiv.org
    Neuron-specific protein expression at striatal excitatory synapses
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    biorxiv.org/content/10.1101/2023.03.16.532957v1
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10175236/
  41. Apr 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC10121225/
  43. Feb 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An enriched environment reduces chronic stress-induced visceral pain through modulating microglial activity in the central nucleus of the amygdala
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    ncbi.nlm.nih.gov/pmc/articles/PMC8793868/
  45. Dec 2022
  46. link.springer.com link.springer.com
    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
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    link.springer.com/article/10.1186/s10020-022-00581-7
  47. Nov 2022
  48. www.researchsquare.com www.researchsquare.com
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  49. Oct 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9574418/
  51. Aug 2022
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    In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification
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    sciencedirect.com/science/article/pii/S0896627322007061
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    Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens
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    ncbi.nlm.nih.gov/pmc/articles/PMC9307248/
  54. www.science.org www.science.org
    Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens
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    science.org/doi/10.1126/sciadv.abo6574
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    Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations
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    sciencedirect.com/science/article/pii/S2352396422003863
  56. May 2022
  57. elifesciences.org elifesciences.org
    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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    elifesciences.org/articles/75233
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination
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    ncbi.nlm.nih.gov/pmc/articles/PMC9053830/
  59. Apr 2022
  60. www.sciencedirect.com www.sciencedirect.com
    POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function
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    sciencedirect.com/science/article/pii/S2211124722003941
  61. journals.physiology.org journals.physiology.org
    An enriched environment reduces chronic stress-induced visceral pain through modulating microglial activity in the central nucleus of the amygdala
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    journals.physiology.org/doi/full/10.1152/ajpgi.00307.2021
  62. Jan 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC8766471/
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    Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
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    sciencedirect.com/science/article/pii/S0092867421015634
  65. Dec 2021
  66. www.sciencedirect.com www.sciencedirect.com
    14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice
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    sciencedirect.com/science/article/pii/S2211124721016016
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    A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function
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    science.org/doi/10.1126/sciadv.abf6935
  68. Nov 2021
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    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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    sciencedirect.com/science/article/pii/S0092867421012320
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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    sciencedirect.com/science/article/pii/S2211124721014121
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    Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action
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    sciencedirect.com/science/article/pii/S2211124721013917
  72. Oct 2021
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    Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function
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    sciencedirect.com/science/article/pii/S2211124721012924
  74. Aug 2021
  75. journals.physiology.org journals.physiology.org
    Amygdala microglia modify neuronal plasticity via complement C1q/C3-CR3 signaling and contribute to visceral pain in a rat model
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    journals.physiology.org/doi/abs/10.1152/ajpgi.00123.2021
  76. www.jneurosci.org www.jneurosci.org
    Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis
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    jneurosci.org/content/34/24/8151
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad180556
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14304
  80. www.jbc.org www.jbc.org
    NMDA receptor–dependent dephosphorylation of serine 387 in Argonaute 2 increases its degradation and affects dendritic spine density and maturation
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    jbc.org/content/293/24/9311.long
  81. Jul 2021
  82. www.frontiersin.org www.frontiersin.org
    Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization
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    Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission
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    sciencedirect.com/science/article/pii/S0028390821002793
  86. May 2021
  87. www.cell.com www.cell.com
    Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies
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    cell.com/neuron/fulltext/S0896-6273(20)30808-4
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    Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility
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    sciencedirect.com/science/article/pii/S0896627320305675
  89. Apr 2021
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    Quantifying molecular aggregation by super resolution microscopy within an excitatory synapse from mouse hippocampal neurons
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  91. Feb 2021
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Truncating mutations in SHANK3 associated with global developmental delay interfere with nuclear β‐catenin signaling
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15014
  93. Dec 2020
  94. www.sciencedirect.com www.sciencedirect.com
    Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
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  95. Oct 2020
  96. molecularautism.biomedcentral.com molecularautism.biomedcentral.com
    Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
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    molecularautism.biomedcentral.com/article/10.1186/s13229-020-00385-8
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7560607/
  98. Sep 2020
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    Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14231
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    Prelimbic cortical targets of ventromedial thalamic projections include inhibitory interneurons and corticostriatal pyramidal neurons in the rat
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    link.springer.com/article/10.1007/s00429-020-02109-3
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    Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease
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    link.springer.com/article/10.1186/s40478-020-01013-5
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    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
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  103. elifesciences.org elifesciences.org
    Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons
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    elifesciences.org/articles/56469
  104. www.embopress.org www.embopress.org
    Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia‐like phenotypes in mice
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    embopress.org/doi/abs/10.15252/embj.2018101090
  105. Jan 2020
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Shank3 regulates striatal synaptic abundance of Cyld, a deubiquitinase specific for Lys63‐linked polyubiquitin chains
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14796
  107. www.jbc.org www.jbc.org
    NMDA receptor–dependent dephosphorylation of serine 387 in Argonaute 2 increases its degradation and affects dendritic spine density and maturation
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    jbc.org/content/293/24/9311.long
  108. www.sciencedirect.com www.sciencedirect.com
    Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons
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  109. www.sciencedirect.com www.sciencedirect.com
    CPG15/Neuritin Mimics Experience in Selecting Excitatory Synapses for Stabilization by Facilitating PSD95 Recruitment
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    A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons
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    sciencedirect.com/science/article/pii/S0165027019304352
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    Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation
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    Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation
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    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
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  114. Nov 2018
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    Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome
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    A Modular Organization of LRR Protein-Mediated Synaptic Adhesion Defines Synapse Identity
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    3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity
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  119. www.jneurosci.org www.jneurosci.org
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    Role for Wnt Signaling in Retinal Neuropil Development: Analysis via RNA-Seq and In Vivo Somatic CRISPR Mutagenesis
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    Differential Regulation of Evoked and Spontaneous Release by Presynaptic NMDA Receptors
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14231/full
  123. Nov 2017
  124. elifesciences.org elifesciences.org
    NPTX2 and cognitive dysfunction in Alzheimer’s Disease
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    elifesciences.org/content/6/e23798
  125. www.sciencedirect.com www.sciencedirect.com
    Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast
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    sciencedirect.com/science/article/pii/S0014488617300857
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density
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    ncbi.nlm.nih.gov/pmc/articles/PMC5040590/
  127. www.jbc.org www.jbc.org
    Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases
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    jbc.org/content/290/8/4908.long
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression
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    ncbi.nlm.nih.gov/pmc/articles/PMC4429152/
  129. www.jneurosci.org www.jneurosci.org
    Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis
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    jneurosci.org/content/34/24/8151