102 Matching Annotations
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    A pooled CRISPR-based neuronal activity screen links TMEM50A-dependent MVB function to synaptic integrity and remote memory
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  3. Jul 2026
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    Localized mRNAs and protein synthesis in cortical layer 1
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  5. Jun 2026
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    Antibody-mediated rescue of endogenous retrovirus-induced damage in the demyelinated central nervous system
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  8. May 2026
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    Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines
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    Gut microbiota-derived ergothioneine alleviates antipsychotic-induced synaptic and cognitive impairments
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    A correlative workflow for synaptic imaging by cryo-electron tomography
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  15. Feb 2026
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    Generation of two tetracycline-inducible NGN2 iN iPSC lines carrying a heterozygous floating-Harbor syndrome SRCAP truncating mutation
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  17. Oct 2025
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    Hide-and-Seek genome editing reveals that Gephyrin is required for axo-axonic synapse assembly
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    Altered NPTX2 dynamics associated with impaired cognitive aging
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    Synaptic pruning following NMDAR-dependent LTD preferentially affects isolated synapses
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    ATM deficiency drives phenotypic diversity and Purkinje cell degeneration in a macaque model of ataxia-telangiectasia
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  23. Aug 2025
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    Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
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    elifesciences.org/articles/97100
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    Novel roles for the GPI-anchor cleaving enzyme, GDE2, in hippocampal synaptic morphology and function
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  26. Jun 2025
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    CXCL12 engages cortical inhibitory neurons to enhance dendritic spine plasticity and structured network activity
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  28. May 2025
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    A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation
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  30. Mar 2025
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  32. Apr 2024
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    Generation of human cerebral organoids with a structured outer subventricular zone
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  34. Mar 2024
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    Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B–/– mice
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    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
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  37. Jan 2024
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    Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication
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    βII-Spectrin Is Required for Synaptic Positioning during Retinal Development
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    Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity
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  42. Nov 2023
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    The proteomic landscape of synaptic diversity across brain regions and cell types
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  44. Aug 2023
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    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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  48. Jul 2023
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    The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
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    Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors
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    Organelle mapping in dendrites of human iPSC-derived neurons reveals dynamic functional dendritic Golgi structures
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  52. May 2023
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    Neuron-specific protein expression at striatal excitatory synapses
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    Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons
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  55. Apr 2023
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    High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly
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  57. Feb 2023
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    An enriched environment reduces chronic stress-induced visceral pain through modulating microglial activity in the central nucleus of the amygdala
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  59. Dec 2022
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    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
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  63. Oct 2022
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    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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  65. Aug 2022
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    In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification
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    Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens
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    Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens
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    Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations
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  70. May 2022
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    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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    Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination
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  73. Apr 2022
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    POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function
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    An enriched environment reduces chronic stress-induced visceral pain through modulating microglial activity in the central nucleus of the amygdala
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  76. Jan 2022
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    Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders
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    Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
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  79. Dec 2021
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    14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice
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  82. Nov 2021
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    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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    Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action
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  86. Oct 2021
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    Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function
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  88. Aug 2021
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    Amygdala microglia modify neuronal plasticity via complement C1q/C3-CR3 signaling and contribute to visceral pain in a rat model
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    Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis
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    NMDA receptor–dependent dephosphorylation of serine 387 in Argonaute 2 increases its degradation and affects dendritic spine density and maturation
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  95. Jul 2021
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    Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization
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    Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission
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  100. May 2021
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    Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies
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    Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility
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  103. Apr 2021
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    Quantifying molecular aggregation by super resolution microscopy within an excitatory synapse from mouse hippocampal neurons
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  105. Feb 2021
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    Truncating mutations in SHANK3 associated with global developmental delay interfere with nuclear β‐catenin signaling
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  107. Dec 2020
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    Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
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  109. Oct 2020
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    Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
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    Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
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  112. Sep 2020
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    Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b
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    Prelimbic cortical targets of ventromedial thalamic projections include inhibitory interneurons and corticostriatal pyramidal neurons in the rat
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    Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease
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    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
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    Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons
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    elifesciences.org/articles/56469
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    Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia‐like phenotypes in mice
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    embopress.org/doi/abs/10.15252/embj.2018101090
  119. Jan 2020
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    Shank3 regulates striatal synaptic abundance of Cyld, a deubiquitinase specific for Lys63‐linked polyubiquitin chains
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14796
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    NMDA receptor–dependent dephosphorylation of serine 387 in Argonaute 2 increases its degradation and affects dendritic spine density and maturation
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    Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons
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    CPG15/Neuritin Mimics Experience in Selecting Excitatory Synapses for Stabilization by Facilitating PSD95 Recruitment
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    A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons
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    Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation
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    Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation
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  128. Nov 2018
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    A Modular Organization of LRR Protein-Mediated Synaptic Adhesion Defines Synapse Identity
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    3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity
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    Role for Wnt Signaling in Retinal Neuropil Development: Analysis via RNA-Seq and In Vivo Somatic CRISPR Mutagenesis
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    Differential Regulation of Evoked and Spontaneous Release by Presynaptic NMDA Receptors
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  137. Nov 2017
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    Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast
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    Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases
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