59 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury: PERK as a potential target for intervention
    1
    1. scibot 11 Dec 2024
      RRID:AB_2095853

      DOI: 10.4103/NRR.NRR-D-23-00794

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    pmc.ncbi.nlm.nih.gov/articles/PMC11624856/
  3. www.sciencedirect.com www.sciencedirect.com
    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
    1
    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.celrep.2024.114984

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    sciencedirect.com/science/article/pii/S2211124724013354
  4. Sep 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pharmacologic activation of activating transcription factor 6 contributes to neuronal survival after spinal cord injury in mice
    1
    1. scibot 27 Sep 2024
      RRID:AB_2095853

      DOI: 10.1111/jnc.16092

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16092
  6. Jun 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes
    1
    1. scibot 08 Jun 2024
      RRID:AB_2095853

      DOI: 10.1016/j.isci.2024.109929

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    sciencedirect.com/science/article/pii/S2589004224011519
  8. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1111/bph.16436

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16436
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
    1
    1. scibot 08 May 2024
      RRID:AB_2095853

      DOI: 10.1016/j.cmet.2024.04.014

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    sciencedirect.com/science/article/pii/S1550413124001347
  11. www.sciencedirect.com www.sciencedirect.com
    Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
    1
    1. scibot 07 May 2024
      Cell SignalingCat#3179

      DOI: 10.1016/j.immuni.2024.04.006

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    sciencedirect.com/science/article/pii/S1074761324002115
  12. Apr 2024
  13. dx.doi.org dx.doi.org
    Acute Exercise Increases GDF15 and Unfolded Protein Response/Integrated Stress Response in Muscle in Type 2 diabetes
    1
    1. scibot 04 Apr 2024
      RRID:AB_2095853

      DOI: 10.1210/clinem/dgae032

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    dx.doi.org/10.1210/clinem/dgae032
  14. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  15. Mar 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease
    1
    1. scibot 27 Mar 2024
      RRID:AB_2095853

      DOI: 10.4103/1673-5374.389356

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960274/
  17. Feb 2024
  18. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
    1
    1. scibot 22 Feb 2024
      RRID:AB_20 95853

      DOI: 10.1101/2023.10.02.560521

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    52.53.155.43/4a182fdd92d1ce35b13f136f7657c6c9ec6a6224/2023.10.02.560521v1.full-html.html
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGF9 is required for Purkinje cell development and function in the cerebellum
    1
    1. scibot 15 Feb 2024
      RRID:AB_2095853

      DOI: 10.1016/j.isci.2024.109039

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863307/
  20. Oct 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
    1
    1. scibot 14 Oct 2023
      RRID:AB_2095853

      DOI: 10.1016/j.isci.2023.107956

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    ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
  22. www.cell.com www.cell.com
    Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
    1
    1. scibot 13 Oct 2023
      RRID:AB_2095853

      DOI: 10.1016/j.isci.2023.108082

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    cell.com/iscience/abstract/S2589-0042(23)02159-4
  23. Sep 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
      RRID:AB_2095853

      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  25. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Dai-html.html
    1
    1. scibot 16 Sep 2023
      AB_2095853

      DOI: 10.1111/bph.16238

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    52.53.155.43/8d076c70ed36377d24eb7bc3686db861bc15751d/British J Pharmacology - 2023 - Dai-html.html
  26. Jul 2023
  27. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD
    1
    1. scibot 12 Jul 2023
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      DOI: 10.1096/fj.202201705RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201705RR
  28. Apr 2023
  29. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
    1
    1. scibot 20 Apr 2023
      RRID:AB_2095853

      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  30. Nov 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
    1
    1. scibot 17 Nov 2022
      RRID:AB_2095853

      DOI: 10.1016/j.cmet.2022.10.011

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    sciencedirect.com/science/article/pii/S1550413122004892
  32. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
    1
    1. scibot 10 Nov 2022
      RRID:AB_2095853

      DOI: 10.1016/j.celrep.2022.111498

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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage
    1
    1. scibot 10 Nov 2022
      RRID:AB_2095853

      DOI: 10.3389/fnagi.2022.967825

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    ncbi.nlm.nih.gov/pmc/articles/PMC9637852/
  34. Sep 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
    1
    1. scibot 24 Sep 2022
      RRID:AB_2095853

      DOI: 10.1016/j.ccell.2022.08.016

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    sciencedirect.com/science/article/pii/S1535610822003804
  36. www.tandfonline.com www.tandfonline.com
    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
    1
    1. scibot 16 Sep 2022
      RRID:AB_2095853

      DOI: 10.1080/15548627.2022.2100105

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    tandfonline.com/doi/abs/10.1080/15548627.2022.2100105
  37. Jul 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation
    1
    1. scibot 13 Jul 2022
      RRID:AB_2095853

      DOI: 10.1016/j.isci.2022.104669

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    sciencedirect.com/science/article/pii/S2589004222009415
  39. www.sciencedirect.com www.sciencedirect.com
    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
    1
    1. scibot 06 Jul 2022
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      DOI: 10.1016/j.cmet.2022.06.007

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    sciencedirect.com/science/article/pii/S1550413122002273
  40. Mar 2022
  41. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
    1
    1. scibot 26 Mar 2022
      RRID:AB_2095853

      DOI: 10.1096/fj.202101555RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101555RR
  42. rupress.org rupress.org
    PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen
    1
    1. scibot 17 Mar 2022
      RRID:AB_2095853

      DOI: 10.1084/jem.20211498

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    rupress.org/jem/article/219/4/e20211498/213062/PERK-reprograms-hematopoietic-progenitor-cells-to
  43. Jan 2022
  44. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Jan 2022
      RRID:AB_2095853

      DOI: 10.1111/bph.15744

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15744
  45. Nov 2021
  46. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Differential ER Stress as a Driver of Cell Fate following Ricin Toxin Exposure
    1
    1. scibot 19 Nov 2021
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      DOI: 10.1096/fba.2021-00005

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fba.2021-00005
  47. www.sciencedirect.com www.sciencedirect.com
    ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
    1
    1. scibot 17 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110003

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    sciencedirect.com/science/article/pii/S2211124721014819
  48. www.sciencedirect.com www.sciencedirect.com
    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
    1
    1. scibot 11 Nov 2021
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      DOI: 10.1016/j.stem.2021.10.009

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    sciencedirect.com/science/article/pii/S1934590921004215
  49. Sep 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Co-opting regulation bypass repair as a gene correction strategy for monogenic diseases
    1
    1. scibot 24 Sep 2021
      3179

      DOI: 10.1016/j.ymthe.2021.04.017

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    sciencedirect.com/science/article/pii/S1525001621002045
  51. Aug 2021
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 09 Aug 2021
      AB_2095853

      DOI: 10.1111/jnc.14537

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14537
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
    1
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      DOI: 10.7554/eLife.69975

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    ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
  54. Jun 2021
  55. www.nature.com www.nature.com
    Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells
    1
    1. scibot 12 Jun 2021
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      DOI: 10.1038/s41467-021-23593-z

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    nature.com/articles/s41467-021-23593-z
  56. May 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.jconrel.2021.03.015

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    sciencedirect.com/science/article/pii/S0168365921001267
  58. www.sciencedirect.com www.sciencedirect.com
    A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation
    1
    1. scibot 01 May 2021
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      DOI: 10.1016/j.cmet.2021.01.013

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    sciencedirect.com/science/article/pii/S1550413121000139
  59. Apr 2021
  60. www.nature.com www.nature.com
    Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals
    1
    1. scibot 01 Apr 2021
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      DOI: 10.1038/s12276-021-00585-z

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    nature.com/articles/s12276-021-00585-z
  61. Sep 2020
  62. www.sciencedirect.com www.sciencedirect.com
    ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress
    1
    1. scibot 23 Sep 2020
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      DOI: 10.1016/j.stem.2020.04.016

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    sciencedirect.com/science/article/pii/S1934590920301557
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    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA‐mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain
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  65. www.sciencedirect.com www.sciencedirect.com
    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
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  66. Jan 2020
  67. academic.oup.com academic.oup.com
    Cartilage ablation of Sirt1 causes inhibition of growth plate chondrogenesis by hyperactivation of mTORC1 signaling
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      DOI: 10.1210/en.2019-00427

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  68. www.sciencedirect.com www.sciencedirect.com
    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
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      DOI: 10.1016/j.cmet.2019.08.021

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  69. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
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      DOI: 10.1016/j.cell.2019.10.015

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    Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration
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  72. www.frontiersin.org www.frontiersin.org
    Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium
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  73. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice
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  77. www.sciencedirect.com www.sciencedirect.com
    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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  78. Nov 2018
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    Vitamin D Switches BAF Complexes to Protect β Cells
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  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chemical hypoxia‐induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (NRF2)
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  84. Nov 2017
  85. www.sciencedirect.com www.sciencedirect.com
    The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling
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