139 Matching Annotations
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    eEF2K regulates pain through translational control of BDNF
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    sciencedirect.com/science/article/pii/S1097276524009481
  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFRD1 is required for maintenance of bladder epithelial homeostasis
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    Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury: PERK as a potential target for intervention
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    Endoplasmic reticulum stress-related deficits in calcium clearance promote neuronal dysfunction that is prevented by SERCA2 gene augmentation
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    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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  8. Sep 2024
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    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
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    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
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    The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress
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    Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway
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  13. Aug 2024
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    An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    Highly specific σ<sub>2</sub>R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response
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      Cell Signaling #3398

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  17. Jul 2024
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    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
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    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer
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    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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  24. Jun 2024
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    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
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  27. May 2024
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    TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage
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    Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
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    Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants
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      Cell signaling3398

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    Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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  34. Apr 2024
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    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
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    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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      3398

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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    sciencedirect.com/science/article/pii/S0092867424003039
  41. Mar 2024
  42. www.embopress.org www.embopress.org
    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
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    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
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    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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    sciencedirect.com/science/article/pii/S2211124724002286
  45. Feb 2024
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    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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    The HRI branch of the integrated stress response selectively triggers mitophagy
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  48. Nov 2023
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    Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis
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  133. May 2021
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    Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
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    Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis
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  163. Nov 2018
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    PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs
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    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
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    High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
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    Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
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    Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses
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    Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
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    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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