134 Matching Annotations
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    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
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    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
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    The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress
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  5. Sep 2024
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    Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway
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  7. Aug 2024
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    An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation
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    sciencedirect.com/science/article/pii/S2211124724009689
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    Highly specific σ<sub>2</sub>R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response
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      Cell Signaling #3398

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  11. Jul 2024
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    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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    1-s2.0-S2589004224017851-main-html.html
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    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
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    cell.com/cell-reports/abstract/S2211-1247(24)00728-9
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    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer
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    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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    cell.com/developmental-cell/fulltext/S1534-5807(24)00382-4
  18. Jun 2024
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    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
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    BPS Publications
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  21. May 2024
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    TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage
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    Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
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    Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants
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    Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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  28. Apr 2024
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    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
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    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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      3398

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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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  35. Mar 2024
  36. www.embopress.org www.embopress.org
    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
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    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
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    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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    sciencedirect.com/science/article/pii/S2211124724002286
  39. Feb 2024
  40. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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    The HRI branch of the integrated stress response selectively triggers mitophagy
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  42. Nov 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
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    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
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    Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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  48. Oct 2023
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  53. Aug 2023
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    Lysosomal cystine governs ferroptosis sensitivity in cancer via cysteine stress response
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    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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    Astrocytic deletion of protein kinase R-like ER kinase (PERK) does not affect learning and memory in aged mice but worsens outcome from experimental stroke
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  67. Mar 2023
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    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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  69. Feb 2023
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    Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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  133. Nov 2020
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  135. Oct 2020
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    Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis
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  156. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Hydrogen sulfide regulates muscle RING finger‐1 protein S‐sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy
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      DOI: 10.1111/bph.14601

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  157. Nov 2018
  158. www.sciencedirect.com www.sciencedirect.com
    PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs
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  160. www.sciencedirect.com www.sciencedirect.com
    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
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    High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
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    Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
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    Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
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    Cannabinoid Receptor Type 1 Agonist ACEA Protects Neurons from Death and Attenuates Endoplasmic Reticulum Stress-Related Apoptotic Pathway Signaling
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  167. Nov 2017
  168. elifesciences.org elifesciences.org
    Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
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    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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