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25 Matching Annotations

Jun 2025
www.sciencedirect.com www.sciencedirect.com

Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.chembiol.2025.05.005
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
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sciencedirect.com/science/article/pii/S2451945625001667
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

1
1. scibot 16 May 2025
  
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  RRID:AB_2099709
  
  DOI: 10.1158/0008-5472.CAN-24-2220
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
Oct 2024
aacrjournals.org aacrjournals.org

Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases

1
1. scibot 02 Oct 2024
  
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  RRID:AB_2099709
  
  DOI: 10.1158/1535-7163.MCT-20-0590
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
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aacrjournals.org/mct/article/20/3/564/92877/Identification-of-Predictive-ERBB-Mutations-by
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer

1
1. scibot 03 Mar 2024
  
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  RRID:AB_2099709
  
  DOI: 10.1101/gad.351037.123
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10621596/
Aug 2023
52.53.155.43 52.53.155.43

L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab

2
1. scibot 18 Aug 2023
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.xcrm.2023.101142
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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  RRID:AB_2099709
2. scibot 10 Aug 2023
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.xcrm.2023.101142
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer

1
1. scibot 23 Jun 2023
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.ccell.2023.05.016
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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sciencedirect.com/science/article/pii/S1535610823001836
Apr 2023
www.nature.com www.nature.com

Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

1
1. scibot 18 Apr 2023
  
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  RRID:AB_2099709
  
  DOI: 10.1038/s41416-023-02264-4
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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nature.com/articles/s41416-023-02264-4
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling

1
1. scibot 22 Nov 2022
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.devcel.2022.10.011
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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sciencedirect.com/science/article/pii/S1534580722007638
Jun 2022
www.jneurosci.org www.jneurosci.org

Disruption of endosomal sorting in Schwann cells leads to defective myelination and endosomal abnormalities observed in Charcot-Marie-Tooth disease

1
1. scibot 23 Jun 2022
  
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  RRID:AB_2099709
  
  DOI: 10.1523/JNEUROSCI.2481-21.2022
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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jneurosci.org/content/42/25/5085
May 2022
aacrjournals.org aacrjournals.org

Triple targeting of HER receptors overcomes heregulin-mediated resistance to EGFR blockade in colorectal cancer

1
1. scibot 14 May 2022
  
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  RRID:AB_2099709
  
  DOI: 10.1158/1535-7163.MCT-21-0818
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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aacrjournals.org/mct/article/21/5/799/694777/Triple-Targeting-of-HER-Receptors-Overcomes
Oct 2021
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Preclinical and Clinical Characterization of Fibroblast-derived Neuregulin-1 on Trastuzumab and Pertuzumab Activity in HER2-positive Breast Cancer

1
1. scibot 01 Oct 2021
  
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  RRID:AB_2099709
  
  DOI: 10.1158/1078-0432.CCR-20-2915
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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clincancerres.aacrjournals.org/content/27/18/5096
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study

1
1. scibot 30 Sep 2021
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.21037/tlcr-21-216
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments

1
1. scibot 18 Aug 2021
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.xcrm.2021.100373
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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sciencedirect.com/science/article/pii/S2666379121002275
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic Functional Annotation of Somatic Mutations in Cancer

1
1. scibot 08 Aug 2021
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.1016/j.ccell.2018.01.021
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
www.sciencedirect.com www.sciencedirect.com

ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

1
1. scibot 03 Aug 2021
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.1016/j.celrep.2021.109455
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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sciencedirect.com/science/article/pii/S221112472100872X
Jul 2021
www.embopress.org www.embopress.org

CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling

1
1. scibot 30 Jul 2021
  
  in Public
  
  p‐HER3
  
  DOI: 10.15252/embr.201948058
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2099709
  
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  RRIDCUR:Missing RRID:AB_2099709
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RRID:AB_2099709

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embopress.org/doi/10.15252/embr.201948058
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic Functional Annotation of Somatic Mutations in Cancer

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID: AB_2099709
  
  DOI: 10.1016/j.ccell.2018.01.021
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:AB_2099709
  
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  RRIDCUR:Unrecognized RRID:AB_2099709
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RRID:AB_2099709

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

1
1. scibot 25 Jun 2021
  
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  RRID:AB_2099709
  
  DOI: 10.1016/j.ccell.2021.06.001
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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  RRID:AB_2099709
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sciencedirect.com/science/article/pii/S1535610821002841
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.1016/j.cmet.2020.10.018
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2099709
  
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sciencedirect.com/science/article/pii/S1550413120305519
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.1016/j.ccell.2020.06.005
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2099709
  
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  RRIDCUR:Validated RRID:AB_2099709
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RRIDCUR:Validated

RRID:AB_2099709

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scibot

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sciencedirect.com/science/article/pii/S1535610820303093
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.7554/eLife.46551
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2099709
  
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  RRID:AB_2099709 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6606022/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2099709
  
  DOI: 10.1016/j.celrep.2018.12.013
  
  Resource: (Cell Signaling Technology Cat# 4791, RRID:AB_2099709)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2099709
  
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  RRID:AB_2099709 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718319247
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2099709
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4791S, RRID:AB_2099709)
  
  SciCrunch record: RRID:AB_2099709
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2099709
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sciencedirect.com/science/article/pii/S1535610818301740
Nov 2017
elifesciences.org elifesciences.org

Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors

1
1. scibot 08 Nov 2017
  
  in Public
  
  pHER3 Y1289
  
  Curator: @gabimpine
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4791S, RRID:AB_2099709)
  
  SciCrunch record: RRID:AB_2099709
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2099709 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:AB_2099709

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scibot

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elifesciences.org/content/3/e04037