Hypothesis

46 Matching Annotations

Nov 2024
www.biorxiv.org www.biorxiv.org

Heterogeneous Effects of Src Inhibition on Determinants of Metastasis in Preclinical Models of Human Bladder Cancer

1
1. scibot 15 Nov 2024
  
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  RRID:AB_2106047
  
  DOI: 10.1101/2024.11.09.622804
  
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biorxiv.org/content/10.1101/2024.11.09.622804v1
Sep 2024
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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

1
1. scibot 25 Sep 2024
  
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  AB_2106047
  
  DOI: 10.1016/j.ccell.2024.08.018
  
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sciencedirect.com/science/article/pii/S1535610824003179
Aug 2024
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Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors

1
1. scibot 01 Aug 2024
  
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  AB_2106047
  
  DOI: 10.1016/j.devcel.2024.07.003
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S1534580724004428
Jul 2024
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ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells

1
1. scibot 19 Jul 2024
  
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  AB_2106047
  
  DOI: 10.1016/j.isci.2024.110273
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S2589004224014986
May 2024
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Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts

1
1. scibot 23 May 2024
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.xcrm.2024.101576
  
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sciencedirect.com/science/article/pii/S2666379124002684
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol to characterize extracellular c-Src tyrosine kinase function through substrate interaction and phosphorylation

1
1. scibot 10 Dec 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.xpro.2023.102755
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10701435/
Oct 2023
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Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer

1
1. scibot 27 Oct 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.celrep.2023.113270
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S2211124723012822
Aug 2023
52.53.155.43 52.53.155.43

PIIS2589004223016838-html.html

1
1. scibot 17 Aug 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.isci.2023.107606
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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52.53.155.43/0595295f970fa120203481e8752220bf0b62043f/PIIS2589004223016838-html.html
May 2023
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PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling

1
1. scibot 27 May 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.celrep.2023.112539
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S2211124723005508
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo

1
1. scibot 26 Mar 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1371/journal.pone.0281063
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10035898/
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

1
1. scibot 23 Feb 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.cmet.2023.01.011
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S1550413123000116
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GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis

1
1. scibot 17 Feb 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.devcel.2023.01.006
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S1534580723000370
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model

1
1. scibot 04 Feb 2023
  
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  RRID:AB_2106047
  
  DOI: 10.3389/fmolb.2023.1058825
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9893022/
Jan 2023
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GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation

1
1. scibot 19 Jan 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.celrep.2023.111997
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S2211124723000086
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy

1
1. scibot 12 Jan 2023
  
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  RRID:AB_2106047
  
  DOI: 10.1158/1535-7163.MCT-21-0964
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9630827/
Oct 2022
www.nature.com www.nature.com

The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma

1
1. scibot 18 Oct 2022
  
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  AB_2106047
  
  DOI: 10.1038/s41419-022-05318-2
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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nature.com/articles/s41419-022-05318-2
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function

1
1. scibot 07 Oct 2022
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.isci.2022.105171
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9530850/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin

1
1. scibot 21 Sep 2022
  
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  AB_2106047
  
  DOI: 10.1016/j.celrep.2022.111390
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047
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sciencedirect.com/science/article/pii/S221112472201227X
Jan 2022
www.sciencedirect.com www.sciencedirect.com

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis

1
1. scibot 13 Jan 2022
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.cell.2021.12.024
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047
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sciencedirect.com/science/article/pii/S0092867421014872
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

1
1. scibot 23 Oct 2021
  
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  RRID:AB_2106047
  
  DOI: 10.7554/eLife.70885
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
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  RRID:AB_2106047
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ncbi.nlm.nih.gov/pmc/articles/PMC8516413/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 20 Oct 2021
  
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  RRID:AB_2106047
  
  DOI: 10.1111/bph.15652
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15652
Aug 2021
academic.oup.com academic.oup.com

Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

1
1. scibot 14 Aug 2021
  
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  RRID:AB_2106047
  
  DOI: 10.1210/en.2019-00177
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
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academic.oup.com/endo/article/160/11/2692/5551999
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase

1
1. scibot 06 Aug 2021
  
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  RRID:AB_2106047
  
  DOI: 10.1523/JNEUROSCI.2519-16.2017
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047
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ncbi.nlm.nih.gov/pmc/articles/PMC6705738/
Jul 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Dopamine D2 receptors are involved in the regulation of fyn and metabotropic glutamate receptor 5 phosphorylation in the rat striatum in vivo

2
1. scibot 30 Jul 2021
  
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  AB_2106047
  
  DOI: 10.1002/jnr.23713
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047
2. scibot 27 Jul 2021
  
  in Public
  
  AB_2106047
  
  DOI: 10.1002/jnr.23713
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @jcabotaj
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047 RRIDCUR:Unrecognized
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RRIDCUR:Unrecognized

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onlinelibrary.wiley.com/doi/10.1002/jnr.23713/full
www.sciencedirect.com www.sciencedirect.com

The Pseudomonas aeruginosa lectin LecA triggers host cell signalling by glycosphingolipid-dependent phosphorylation of the adaptor protein CrkII

7
1. scibot 27 Jul 2021
  
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  RRID:AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Cell Signaling Technology Cat# 2123, Src (32G6) Rabbit mAb antibody
  
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  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
2. scibot 27 Jul 2021
  
  in Public
  
  AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
3. scibot 27 Jul 2021
  
  in Public
  
  AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
4. scibot 27 Jul 2021
  
  in Public
  
  AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Cell Signaling Technology Cat# 2123, Src (32G6) Rabbit mAb antibody
  
  What is this?
  
  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
5. scibot 27 Jul 2021
  
  in Public
  
  AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Cell Signaling Technology Cat# 2123,
  
  What is this?
  
  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
6. scibot 27 Jul 2021
  
  in Public
  
  AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Src (32G6) Rabbit MAb Antibody Cell Signaling Technology Cat# 2123 also 2123S, 2123P
  
  What is this?
  
  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
7. scibot 27 Jul 2021
  
  in Public
  
  AB_10695000
  
  DOI: 10.1016/j.bbamcr.2017.04.005
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Zeljana_Babic
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047 RRIDCUR:Unresolved RRIDCUR:Incorrect
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RRIDCUR:Incorrect

RRID:AB_2106047

RRIDCUR:Unresolved

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sciencedirect.com/science/article/pii/S016748891730099X
Jun 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Roles of adenosine A1 receptors in the regulation of SFK activity in the rat forebrain

1
1. scibot 26 Jun 2021
  
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  RRID:AB_2106047
  
  DOI: 10.1002/brb3.2254
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
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  RRID:AB_2106047
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onlinelibrary.wiley.com/doi/10.1002/brb3.2254
www.sciencedirect.com www.sciencedirect.com

Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma

1
1. scibot 18 Jun 2021
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.ccell.2021.05.015
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047
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sciencedirect.com/science/article/pii/S1535610821002816
Jan 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 08 Jan 2021
  
  in Public
  
  RRID:AB_2106047
  
  DOI: 10.1111/bph.15306
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15306
Nov 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth

1
1. scibot 07 Nov 2020
  
  in Public
  
  anti-Src
  
  DOI: 10.1016/j.celrep.2020.108332
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Src (32G6) Rabbit mAb antibody Cell Signaling Technology Cat# 2123
  
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  RRIDCUR:Missing RRID:AB_2106047
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RRIDCUR:Missing

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pubmed.ncbi.nlm.nih.gov/33147457/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Linkage of Non-receptor Tyrosine Kinase Fyn to mGlu5 Receptors in Striatal Neurons in a Depression Model

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:AB_2106047
  
  DOI: 10.1016/j.neuroscience.2020.02.048
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2106047
  
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  RRID:AB_2106047 RRIDCUR:Validated
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RRID:AB_2106047

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S030645222030141X
www.sciencedirect.com www.sciencedirect.com

Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:AB_2106047
  
  DOI: 10.1016/j.celrep.2020.02.012
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124720301662
onlinelibrary.wiley.com onlinelibrary.wiley.com

Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity

1
1. scibot 15 Sep 2020
  
  in Public
  
  RRID:AB_2106047
  
  DOI: 10.1111/jnc.14960
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Naa003
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14960
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer

1
1. scibot 13 Sep 2020
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.ebiom.2020.102988
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Src (32G6) Rabbit mAb antibody Cell Signaling Technology Cat# 2123
  
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  RRID:AB_2106047
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pubmed.ncbi.nlm.nih.gov/32927276/
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Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway

1
1. scibot 10 Sep 2020
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.celrep.2020.01.037
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @ethanbadger
  
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  RRID:AB_2106047 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720300528
onlinelibrary.wiley.com onlinelibrary.wiley.com

Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness

1
1. scibot 04 Sep 2020
  
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  Src
  
  DOI: 10.1002/ijc.32955
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2106047
  
  Curator comments: Src (32G6) Rabbit mAb antibody Cell Signaling Technology Cat# 2123
  
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  RRID:AB_2106047 RRIDCUR:Missing
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onlinelibrary.wiley.com/doi/10.1002/ijc.32955
Jan 2020
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Untitled document

1
1. scibot 12 Jan 2020
  
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  RRID:AB_2106047
  
  DOI: 10.1016/j.chembiol.2019.02.021
  
  Resource: (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2451945619300765
Nov 2018
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Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2106047
  
  Curator: @evieth
  
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  (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S2451945617303549
Nov 2017
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Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

1
1. scibot 08 Nov 2017
  
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  AB_2106047
  
  Curator: @chewbeccax
  
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  (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
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sciencedirect.com/science/article/pii/S1934590917301376
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

1
1. scibot 08 Nov 2017
  
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  2123
  
  Curator: @bandrow
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2123, RRID:AB_2106047)
  
  SciCrunch record: RRID:AB_2106047
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4931344/