145 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.immuni.2024.11.001

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    sciencedirect.com/science/article/pii/S1074761324004965
  3. Nov 2024
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    Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus
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    1. scibot 17 Nov 2024
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      DOI: 10.1016/j.celrep.2024.114978

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    sciencedirect.com/science/article/pii/S2211124724013299
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    Decoding transcriptional identity in developing human sensory neurons and organoid modeling
    1
    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.cell.2024.10.023

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    sciencedirect.com/science/article/pii/S0092867424012054
  6. Sep 2024
  7. www.sciencedirect.com www.sciencedirect.com
    A TBK1-independent primordial function of STING in lysosomal biogenesis
    1
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    sciencedirect.com/science/article/pii/S1097276524007032
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New dual inducible cellular model to investigate temporal control of oncogenic cooperating genes
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1038/s41598-024-71227-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11377716/
  9. Aug 2024
  10. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.cmet.2017.10.006

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    sciencedirect.com/science/article/pii/S1550413117306186
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    Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis
    1
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    sciencedirect.com/science/article/pii/S1550413124002808
  12. www.cell.com www.cell.com
    Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility
    1
    1. scibot 18 Aug 2024
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    cell.com/cell-reports/fulltext/S2211-1247(24)00911-2
  13. May 2024
  14. www.cell.com www.cell.com
    Regulation of Foxo1 expression is critical for central B cell tolerance and allelic exclusion
    1
    1. scibot 30 May 2024
      RRID:AB_2106495

      DOI: 10.1016/j.celrep.2024.114283

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    cell.com/cell-reports/abstract/S2211-1247(24)00611-9
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage
    1
    1. scibot 22 May 2024
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      DOI: 10.1186/s12967-024-05253-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11103838/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective effects of G9a inhibition through modulation of peroxisome-proliferator activator receptor gamma-dependent pathways by miR-128
    1
    1. scibot 15 May 2024
      AB_2106495

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    ncbi.nlm.nih.gov/pmc/articles/PMC11090428/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Long Non-Coding RNA Gene AC027288.3 Plays a Role in Human Endometrial Stromal Fibroblast Decidualization
    1
    1. scibot 15 May 2024
      RRID:AB_2106495

      DOI: 10.3390/cells13090778

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    ncbi.nlm.nih.gov/pmc/articles/PMC11083667/
  18. www.mdpi.com www.mdpi.com
    IL17A Suppresses IGFBP1 in Human Endometrial Stromal Cells
    1
    1. scibot 03 May 2024
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      DOI: 10.3390/reprodmed5020006

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    mdpi.com/2673-3897/5/2/6
  19. Apr 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
  21. www.sciencedirect.com www.sciencedirect.com
    hnRNPU is required for spermatogonial stem cell pool establishment in mice
    1
    1. scibot 19 Apr 2024
      CSTC29H4

      DOI: 10.1016/j.celrep.2024.114113

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    sciencedirect.com/science/article/pii/S2211124724004418
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    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.xgen.2024.100537

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    sciencedirect.com/science/article/pii/S2666979X24000934
  23. Mar 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats
    1
    1. scibot 09 Mar 2024
      AB_2106495

      DOI: 10.14814/phy2.15969

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXO1 stimulates tip cell-enriched gene expression in endothelial cells
    1
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109161

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    ncbi.nlm.nih.gov/pmc/articles/PMC10914484/
  26. Feb 2024
  27. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 27 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
    1
    1. scibot 14 Feb 2024
      RRID:AB_2106495

      DOI: 10.1126/sciadv.adi4935

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
      RRID:AB_2106495

      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  30. Jan 2024
  31. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 10 Jan 2024
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
    1
    1. scibot 29 Nov 2023
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      DOI: 10.1016/j.isci.2023.108352

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    sciencedirect.com/science/article/pii/S258900422302429X
  34. Oct 2023
  35. www.sciencedirect.com www.sciencedirect.com
    PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113329

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    sciencedirect.com/science/article/pii/S2211124723013414
  36. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
    1
    1. scibot 07 Oct 2023
      RRID:AB_2106495

      DOI: 10.1158/2767-9764.CRC-23-0119

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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  37. www.cmghjournal.org www.cmghjournal.org
    Hepatocyte FoxO1 deficiency protects from liver fibrosis via reducing inflammation and TGF-β1 mediated HSC activation
    1
    1. scibot 07 Oct 2023
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      DOI: 10.1016/j.jcmgh.2023.08.013

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    cmghjournal.org/article/S2352-345X(23)00161-3/abstract
  38. Sep 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation
    1
    1. scibot 21 Sep 2023
      AB_2106495

      DOI: 10.1016/j.mce.2021.111264

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    sciencedirect.com/science/article/pii/S0303720721001088
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    PARP1 inhibition protects mice against Japanese encephalitis virus infection
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113103

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    sciencedirect.com/science/article/pii/S2211124723011142
  41. Jul 2023
  42. www.sciencedirect.com www.sciencedirect.com
    GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis
    1
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      DOI: 10.1016/j.isci.2023.107293

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    sciencedirect.com/science/article/pii/S2589004223013706
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    GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells
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      DOI: 10.1016/j.isci.2023.107341

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    sciencedirect.com/science/article/pii/S2589004223014189
  44. www.nature.com www.nature.com
    Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
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      DOI: 10.1038/s41467-023-39715-8

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    nature.com/articles/s41467-023-39715-8
  45. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD
    1
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      DOI: 10.1096/fj.202201705RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201705RR
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of spermatogonial stem cells in testicular tissue of dogs with chronic asymptomatic orchitis
    1
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      DOI: 10.3389/fvets.2023.1205064

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    ncbi.nlm.nih.gov/pmc/articles/PMC10311113/
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Identification of XAF1 as an endogenous AKT inhibitor
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      DOI: 10.1016/j.celrep.2023.112690

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    sciencedirect.com/science/article/pii/S2211124723007015
  49. May 2023
  50. 52.53.155.43 52.53.155.43
    PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis
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      DOI: 10.1210/endocr/bqad065

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  51. www.sciencedirect.com www.sciencedirect.com
    Asymmetric cell division safeguards memory CD8 T cell development
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      DOI: 10.1016/j.celrep.2023.112468

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    sciencedirect.com/science/article/pii/S2211124723004795
  52. academic.oup.com academic.oup.com
    Uterine epithelial progesterone receptor governs uterine receptivity through epithelial cell differentiation
    1
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      DOI: 10.1210/endocr/bqaa195

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    academic.oup.com/endo/article/161/12/bqaa195/5939206
  53. Apr 2023
  54. www.sciencedirect.com www.sciencedirect.com
    CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice
    1
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      DOI: 10.1016/j.isci.2023.106524

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    sciencedirect.com/science/article/pii/S2589004223006016
  55. Mar 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats
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      DOI: 10.1152/ajpendo.00240.2021

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  57. Feb 2023
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    Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1
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  59. Dec 2022
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    Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis
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  61. Nov 2022
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    Activation of Wnt/β-catenin signaling by Zeb1 in endothelial progenitors induces vascular quiescence entry
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    Ageing Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Human
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  64. Oct 2022
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    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
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    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
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    E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
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  68. Sep 2022
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    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
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  70. Aug 2022
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    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
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    Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia
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  74. Jul 2022
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    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
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    British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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    Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation
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    Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy
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  79. May 2022
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  81. Feb 2022
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    Imatinib and methazolamide ameliorate COVID-19-induced metabolic complications via elevating ACE2 enzymatic activity and inhibiting viral entry
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    FOXO transcription factors are required for normal somatotrope function and growth
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  84. Jan 2022
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    C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis
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  86. Dec 2021
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    Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
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    TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver
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    Effect of miR-183-5p on Cholestatic Liver Fibrosis by Regulating Fork Head Box Protein O1 Expression
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  92. Nov 2021
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    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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    Transcriptional regulation of LGALS9 by HAND2 and FOXO1 in human endometrial stromal cells in women with regular cycles
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    CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development
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  97. Oct 2021
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    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
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    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
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    Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
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    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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