112 Matching Annotations
  1. Last 7 days
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    Deletion of the SHORT Syndrome Gene Prkce Results in Brain Atrophy and Cognitive and Motor Behavior Deficits in Mice
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    link.springer.com/article/10.1007/s12264-025-01497-y
  3. Aug 2025
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    Protocol for assessing auditory function, cochlear synaptopathy, and afferent terminal morphology in laboratory mice
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    sciencedirect.com/science/article/pii/S2666166725004460
  5. Jun 2025
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    Combinatorial transcriptional regulation establishes subtype-appropriate synaptic properties in auditory neurons
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    sciencedirect.com/science/article/pii/S2211124725005674
  7. Feb 2025
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    Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11938102/
  10. Jan 2025
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    Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome
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    sciencedirect.com/science/article/pii/S2589004224029079
  13. Sep 2024
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    MDGAs perform activity-dependent synapse type-specific suppression via distinct extracellular mechanisms
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    pnas.org/doi/10.1073/pnas.2322978121
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    Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11380428/
  16. Aug 2024
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Large basolateral processes on type II hair cells are novel processing units in mammalian vestibular organs
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    onlinelibrary.wiley.com/doi/10.1002/cne.23625/full
  18. Jul 2024
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    The Chemokine CCL2 Promotes Excitatory Synaptic Transmission in Hippocampal Neurons via GluA1 Subunit Trafficking
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    link.springer.com/article/10.1007/s12264-024-01236-9
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    From hidden hearing loss to supranormal auditory processing by neurotrophin 3-mediated modulation of inner hair cell synapse density
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210788/
  21. May 2024
  22. www.jneurosci.org www.jneurosci.org
    Age-related deficits in binaural hearing: Contribution of peripheral and central effects
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    jneurosci.org/content/44/16/e0963222024
  23. Apr 2024
  24. www.sciencedirect.com www.sciencedirect.com
    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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    sciencedirect.com/science/article/pii/S221112472400353X
  25. Mar 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cochlear Ribbon Synapses in Aged Gerbils
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    ncbi.nlm.nih.gov/pmc/articles/PMC10931817/
  27. Feb 2024
  28. www.biorxiv.org www.biorxiv.org
    Female mice lacking GluA3 show early onset of hearing loss, synaptopathy, and afferent swellings in ambient sound levels
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    biorxiv.org/content/10.1101/2024.02.21.581467v1
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  30. Dec 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation
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    sciencedirect.com/science/article/pii/S2589004223027566
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    Purkinje-cell-specific MeCP2 deficiency leads to motor deficits and autistic-like behavior due to aberrations in PTP1B-TrkB-SK signaling
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    sciencedirect.com/science/article/pii/S2211124723015711
  33. Oct 2023
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Absence of Embigin accelerates hearing loss and causes sub-viability, brain and cardiac defects in C57BL/6N mice due to interaction with Cdh23ahl
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    pmc.ncbi.nlm.nih.gov/articles/PMC10579432/
  35. Sep 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC2 regulates auditory hair cell structure and function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10484995/
  37. Jun 2023
  38. www.jneurosci.org www.jneurosci.org
    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
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    jneurosci.org/content/43/15/2631
  39. May 2023
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    Inhibiting neuronal AC1 for treating anxiety and headache in the animal model of migraine
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  41. Apr 2023
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    A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging
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    sciencedirect.com/science/article/pii/S2211124723004412
  43. Mar 2023
  44. link.springer.com link.springer.com
    Sepsis Impairs Purkinje Cell Functions and Motor Behaviors Through Microglia Activation
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    link.springer.com/article/10.1007/s12311-023-01531-7
  45. Feb 2023
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Translational patterns of ionotropic glutamate and GABA receptors during brain development and behavioral stimuli revealed by polysome profiling
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    onlinelibrary.wiley.com/doi/epdf/10.1111/jnc.15771
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GluA3 subunits are required for appropriate assembly of AMPAR GluA2 and GluA4 subunits on cochlear afferent synapses and for presynaptic ribbon modiolar–pillar morphology
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    ncbi.nlm.nih.gov/pmc/articles/PMC9891727/
  48. Oct 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Noise-induced hearing loss vulnerability in type III intermediate filament peripherin gene knockout mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9549866/
  50. Aug 2022
  51. www.sciencedirect.com www.sciencedirect.com
    In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification
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    sciencedirect.com/science/article/pii/S0896627322007061
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    Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3
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    sciencedirect.com/science/article/pii/S2589004222010756
  53. Jun 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Prkn knockout mice show autistic-like behaviors and aberrant synapse formation
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    sciencedirect.com/science/article/pii/S2589004222008458
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    Expansion microscopy of mouse brain organotypic slice cultures to study protein distribution
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    Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors
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    sciencedirect.com/science/article/pii/S2667242122000379
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    Optical analysis of AMPAR-mediated synaptic scaling in mouse hippocampus
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    sciencedirect.com/science/article/pii/S2666166722003239
  58. Feb 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing
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    ncbi.nlm.nih.gov/pmc/articles/PMC8830789/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization
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    ncbi.nlm.nih.gov/pmc/articles/PMC8828051/
  61. Jan 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Characterizing neurotrophic factor-induced synaptic growth in primary mouse neuronal cultures
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    sciencedirect.com/science/article/pii/S2666166721008182
  63. Nov 2021
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    Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action
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    sciencedirect.com/science/article/pii/S2211124721013917
  65. Oct 2021
  66. www.jneurosci.org www.jneurosci.org
    The differentiation status of hair cells that regenerate naturally in the vestibular inner ear of the adult mouse
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    jneurosci.org/content/41/37/7779
  67. Sep 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Age-related decline in cochlear ribbon synapses and its relation to different metrics of auditory-nerve activity
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    sciencedirect.com/science/article/pii/S0197458021002736
  69. Aug 2021
  70. www.sciencedirect.com www.sciencedirect.com
    NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
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    sciencedirect.com/science/article/pii/S2211124721009451
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain
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    onlinelibrary.wiley.com/doi/10.1002/cne.24792
  72. www.eneuro.org www.eneuro.org
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    eneuro.org/content/4/4/eneuro.0040-17.2017
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    ncbi.nlm.nih.gov/pmc/articles/PMC6347813/
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.23625
  77. www.nature.com www.nature.com
    Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure
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    nature.com/articles/s41598-017-01142-3
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    Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8296521/
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    Electrical stimulation induces synaptic changes in the peripheral auditory system
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  83. Jul 2021
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    Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events
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    ncbi.nlm.nih.gov/pmc/articles/PMC6307864/
  86. www.frontiersin.org www.frontiersin.org
    Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization
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    frontiersin.org/articles/10.3389/fncel.2019.00330/full
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thorase variants cause defects in glutamatergic signaling and behavioral deficits: rescue by Perampanel.
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    ncbi.nlm.nih.gov/pmc/articles/PMC6573025/
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    Differing intrinsic biological properties between forebrain and spinal oligodendroglial lineage cells
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14074
  89. www.jneurosci.org www.jneurosci.org
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    jneurosci.org/content/34/45/14919
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    A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex
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    sciencedirect.com/science/article/pii/S0896627317304609
  91. www.nature.com www.nature.com
    Cerebellin-2 regulates a serotonergic dorsal raphe circuit that controls compulsive behaviors
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    nature.com/articles/s41380-021-01187-x
  92. May 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
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    sciencedirect.com/science/article/pii/S2589004221004727
  94. Apr 2021
  95. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Cochlear protection against noise exposure requires serotonin type 3A receptor via the medial olivocochlear system
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002383R
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    EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity
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    sciencedirect.com/science/article/pii/S2211124721002370
  97. Feb 2021
  98. academic.oup.com academic.oup.com
    Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring
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    academic.oup.com/endo/article/162/1/bqaa214/5992137
  99. journals.plos.org journals.plos.org
    SIRT3 promotes auditory function in young adult FVB/nJ mice but is dispensable for hearing recovery after noise exposure
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    journals.plos.org/plosone/article
  100. Dec 2020
  101. www.sciencedirect.com www.sciencedirect.com
    Noise Exposures Causing Hearing Loss Generate Proteotoxic Stress and Activate the Proteostasis Network
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    sciencedirect.com/science/article/pii/S2211124720314200
  102. Nov 2020
  103. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyotrophic lateral sclerosis associated mislocalisation of TDP‐43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15214
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    Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity
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  105. Sep 2020
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14231
  107. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Correcting abnormalities in miR‐124/PTPN1 signaling rescues tau pathology in Alzheimer’s disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14961
  108. www.jneurosci.org www.jneurosci.org
    The LMTK1—TBC1D9B—Rab11A cascade regulates dendritic spine formation via endosome trafficking
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    jneurosci.org/content/39/48/9491
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior
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    ncbi.nlm.nih.gov/pmc/articles/PMC7032715/
  110. www.thelancet.com www.thelancet.com
    GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(18)30543-7/fulltext
  111. Jan 2020
  112. www.jneurosci.org www.jneurosci.org
    AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder
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    jneurosci.org/content/39/24/4814
  113. www.sciencedirect.com www.sciencedirect.com
    A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons
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    sciencedirect.com/science/article/pii/S0165027019304352
  114. www.sciencedirect.com www.sciencedirect.com
    Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling
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    sciencedirect.com/science/article/pii/S0896627319307019
  115. www.sciencedirect.com www.sciencedirect.com
    The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling
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    sciencedirect.com/science/article/pii/S2211124719311532
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    Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression
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    sciencedirect.com/science/article/pii/S2211124719307636
  117. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-019-0427-6
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events
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    ncbi.nlm.nih.gov/pmc/articles/PMC6307864/
  119. Nov 2018
  120. www.nature.com www.nature.com
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    nature.com/articles/s41467-018-05125-4
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    Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors
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    sciencedirect.com/science/article/pii/S0896627318308456
  122. www.sciencedirect.com www.sciencedirect.com
    Long-Term Potentiation Requires a Rapid Burst of Dendritic Mitochondrial Fission during Induction
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    sciencedirect.com/science/article/pii/S0896627318308274
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    Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression
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    sciencedirect.com/science/article/pii/S0896627318306834
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Computational Synaptic Antibody Characterization Tool for Array Tomography
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