12 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
    1
    1. scibot 24 Nov 2024
      RRID:AB_2114489

      DOI: 10.1016/j.celrep.2024.114985

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @scibot

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489
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    sciencedirect.com/science/article/pii/S2211124724013366
  3. Feb 2024
  4. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia
    2
    1. scibot 22 Feb 2024
      RRID:AB_2114489

      DOI: 10.1186/s12974-024-03039-1

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @scibot

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489
    2. scibot 15 Feb 2024
      RRID:AB_2114489

      DOI: 10.1186/s12974-024-03039-1

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @scibot

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489
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    jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-024-03039-1
  5. Oct 2023
  6. www.sciencedirect.com www.sciencedirect.com
    SorCS2 binds progranulin to regulate motor neuron development
    1
    1. scibot 28 Oct 2023
      RRID:AB_2114489

      DOI: 10.1016/j.celrep.2023.113333

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @scibot

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489
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    sciencedirect.com/science/article/pii/S2211124723013451
  7. Jul 2023
  8. www.sciencedirect.com www.sciencedirect.com
    AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice
    1
    1. scibot 15 Jul 2023
      RRID:AB_2114489

      DOI: 10.1016/j.isci.2023.107247

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @scibot

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489
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    sciencedirect.com/science/article/pii/S258900422301324X
  9. Aug 2021
  10. www.sciencedirect.com www.sciencedirect.com
    Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
    1
    1. scibot 27 Aug 2021
      RRID:AB_2114489

      DOI: 10.1016/j.cell.2021.08.002

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0092867421009442
  11. academic.oup.com academic.oup.com
    Female-Specific Role of Progranulin to Suppress Bone Formation
    1
    1. scibot 01 Aug 2021
      RRID:AB_2114489

      DOI: 10.1210/en.2018-00842

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2114489

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      RRIDCUR:Validated RRID:AB_2114489
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    academic.oup.com/endo/article/160/9/2024/5522004
  12. Jul 2021
  13. www.sciencedirect.com www.sciencedirect.com
    Delivering progranulin to neuronal lysosomes protects against excitotoxicity
    2
    1. scibot 24 Jul 2021
      AF2420

      DOI: 10.1016/j.jbc.2021.100993

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489 RRIDCUR:Missing
    2. scibot 24 Jul 2021
      AF2420

      DOI: 10.1016/j.jbc.2021.100993

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S002192582100795X
  14. Oct 2020
  15. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GRN, NOTCH3, FN1, and PINK1 expression in eutopic endometrium – potential biomarkers in the detection of endometriosis – a pilot study
    1
    1. scibot 13 Oct 2020
      RRID:AB_2114489

      DOI: 10.1007/s10815-020-01905-4

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489 RRIDCUR:Validated
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    pubmed.ncbi.nlm.nih.gov/33029756/
  16. Jan 2020
  17. www.sciencedirect.com www.sciencedirect.com
    CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
    1
    1. scibot 13 Jan 2020
      RRID:AB_2114489

      DOI: 10.1016/j.neuron.2019.07.014

      Resource: (R and D Systems Cat# AF2420, RRID:AB_2114489)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2114489

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      RRID:AB_2114489 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319306403
  18. Nov 2018
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C
    1
    1. scibot 05 Nov 2018
      RRID:AB_2114489

      Curator: @Jmenke

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      (R and D Systems Cat# AF2420, RRID:AB_2114489)

      SciCrunch record: RRID:AB_2114489

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2114489
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14110