34 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115026

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    sciencedirect.com/science/article/pii/S2211124724013779
  3. Feb 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions
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    1. scibot 28 Feb 2024
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      DOI: 10.4103/1673-5374.386398

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    ncbi.nlm.nih.gov/pmc/articles/PMC10883507/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
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    1. scibot 21 Feb 2024
      RRID:AB_2115196

      DOI: 10.1158/2767-9764.CRC-23-0379

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    ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
  6. Oct 2023
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
    1
    1. scibot 20 Oct 2023
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      DOI: 10.7554/eLife.88279

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581688/
  8. Jun 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Identification of XAF1 as an endogenous AKT inhibitor
    1
    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112690

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    sciencedirect.com/science/article/pii/S2211124723007015
  10. www.sciencedirect.com www.sciencedirect.com
    Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
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    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.isci.2023.107047

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    sciencedirect.com/science/article/pii/S2589004223011240
  11. Apr 2023
  12. www.biorxiv.org www.biorxiv.org
    Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
    1
    1. scibot 28 Apr 2023
      RRID:AB_2115196

      DOI: 10.1101/2023.04.05.535722

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    biorxiv.org/content/10.1101/2023.04.05.535722v3
  13. Mar 2023
  14. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 Mar 2023
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      DOI: 10.1111/bph.16046

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16046
  15. Feb 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
    1
    1. scibot 15 Feb 2023
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      DOI: 10.3233/ADR-220056

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    ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
  17. Sep 2022
  18. www.authorea.com www.authorea.com
    ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth
    1
    1. scibot 22 Sep 2022
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      DOI: 10.22541/au.166126327.70529620/v1

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    authorea.com/users/503180/articles/582965-isx9-a-small-molecule-targeting-axin-activates-wnt-β-catenin-signaling-and-promotes-hair-regrowth
  19. Aug 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia
    1
    1. scibot 27 Aug 2022
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      DOI: 10.3390/ijms23169375

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    ncbi.nlm.nih.gov/pmc/articles/PMC9409400/
  21. Sep 2021
  22. www.sciencedirect.com www.sciencedirect.com
    KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis
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    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.molcel.2021.09.001

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    sciencedirect.com/science/article/pii/S1097276521007358
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β-catenin signaling pathways
    1
    1. scibot 04 Sep 2021
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      DOI: 10.1002/jbt.22905

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    onlinelibrary.wiley.com/doi/10.1002/jbt.22905
  24. Aug 2021
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK3-CRMP2 signaling mediates axonal regeneration induced by Pten knockout
    2
    1. scibot 02 Aug 2021
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      DOI: 10.1038/s42003-019-0524-1

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    2. scibot 01 Aug 2021
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      DOI: 10.1038/s42003-019-0524-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC6707209/
  26. Jul 2021
  27. academic.oup.com academic.oup.com
    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
    1
    1. scibot 31 Jul 2021
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      DOI: 10.1210/en.2019-00118

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    academic.oup.com/endo/article/160/5/1179/5434897
  28. www.pnas.org www.pnas.org
    Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1073/pnas.1621225114

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    pnas.org/content/114/27/E5454.full
  29. www.sciencedirect.com www.sciencedirect.com
    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1016/j.xcrm.2021.100350

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    sciencedirect.com/science/article/pii/S2666379121001993
  30. May 2021
  31. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.molcel.2020.07.028

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    sciencedirect.com/science/article/pii/S1097276520305190
  32. www.sciencedirect.com www.sciencedirect.com
    AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.05.026

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    sciencedirect.com/science/article/pii/S1534580720304159
  33. www.sciencedirect.com www.sciencedirect.com
    A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.cmet.2021.04.006

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    sciencedirect.com/science/article/pii/S1550413121001728
  34. Mar 2021
  35. www.sciencedirect.com www.sciencedirect.com
    SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells
    1
    1. scibot 17 Mar 2021
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      DOI: 10.1016/j.celrep.2021.108821

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    sciencedirect.com/science/article/pii/S2211124721001352
  36. Feb 2021
  37. academic.oup.com academic.oup.com
    Myeloid-derived Growth Factor Promotes Intestinal Glucagon-like Peptide-1 Production in Male Mice with Type 2 Diabetes
    1
    1. scibot 24 Feb 2021
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      DOI: 10.1210/endocr/bqaa003

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    academic.oup.com/endo/article/161/2/bqaa003/5698328
  38. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
    1
    1. scibot 24 Feb 2021
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      DOI: 10.1016/j.celrep.2021.108744

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    sciencedirect.com/science/article/pii/S2211124721000577
  39. Oct 2020
  40. www.sciencedirect.com www.sciencedirect.com
    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
    1
    1. scibot 08 Oct 2020
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      DOI: 10.1016/j.celrep.2020.108223

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    sciencedirect.com/science/article/pii/S2211124720312122
  41. Sep 2020
  42. www.mdpi.com www.mdpi.com
    Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species
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    1. scibot 15 Sep 2020
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      DOI: 10.3390/ijms21144970

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    mdpi.com/1422-0067/21/14/4970
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Sep 2020
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      DOI: 10.1111/bph.15182

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
  44. www.sciencedirect.com www.sciencedirect.com
    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
    1
    1. scibot 08 Sep 2020
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      DOI: 10.1016/j.cmet.2020.03.007

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    sciencedirect.com/science/article/pii/S1550413120301224
  45. Jan 2020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK3-CRMP2 signaling mediates axonal regeneration induced by Pten knockout
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1038/s42003-019-0524-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC6707209/
  47. www.sciencedirect.com www.sciencedirect.com
    IMM-H004 reduced okadaic acid-induced neurotoxicity by inhibiting Tau pathology in vitro and in vivo
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.neuro.2019.09.012

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    sciencedirect.com/science/article/pii/S0161813X19301020
  48. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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      DOI: 10.1016/j.ccell.2019.10.001

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    sciencedirect.com/science/article/pii/S1535610819304398
  49. academic.oup.com academic.oup.com
    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1210/en.2019-00118

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    academic.oup.com/endo/article/160/5/1179/5434897
  50. Nov 2018
  51. www.sciencedirect.com www.sciencedirect.com
    The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells
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    sciencedirect.com/science/article/pii/S1097276518301084
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    Untitled document
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    sciencedirect.com/science/article/pii/S1074761318300700