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Targeted extracellular vesicle-photoimmunotherapy remodels stromal-immune microenvironment to boost chemo-immunotherapy in preclinical models

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  DOI: 10.1016/j.xcrm.2026.102843
  
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sciencedirect.com/science/article/pii/S2666379126002600
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HSPA6 maintains IMPDH2 phosphorylation to regulate GTP synthesis for driving radioresistance of glioblastoma stem cells

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1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117490
  
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sciencedirect.com/science/article/pii/S2211124726005681
May 2026
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Design principles of a membrane-spanning ubiquitin ligase

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1. scibot 29 May 2026
  
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  DOI: 10.1016/j.molcel.2026.05.001
  
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sciencedirect.com/science/article/pii/S1097276526003072
Feb 2026
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Intratumoral bacterium Enterocloster bolteae promotes hepatocellular carcinoma progression by directly binding tumor cells

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.chom.2026.01.020
  
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sciencedirect.com/science/article/pii/S1931312826000454
Nov 2025
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A triple-action PROTAC for wild-type p53 cancer therapy

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102467
  
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sciencedirect.com:5037/science/article/pii/S2666379125005403
Oct 2025
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Structure and function of a pair of non-competing monoclonal antibodies against Langya henipavirus attachment glycoprotein

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116407
  
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sciencedirect.com/science/article/pii/S2211124725011787
Aug 2025
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AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

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1. scibot 13 Aug 2025
  
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  DOI: 10.1126/sciadv.adv2453
  
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science.org/doi/10.1126/sciadv.adv2453
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AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

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1. scibot 12 Aug 2025
  
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  DOI: 10.1126/sciadv.adv2453
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12327453/
Apr 2025
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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115595
  
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sciencedirect.com/science/article/pii/S2211124725003663
Mar 2025
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VIPAS39 confers ferroptosis resistance in epithelial ovarian cancer through exporting ACSL4

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.ebiom.2025.105646
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11957506/
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The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115365
  
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sciencedirect.com/science/article/pii/S2211124725001366
Feb 2025
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HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR-mediated INSIG phosphorylation

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115339
  
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sciencedirect.com/science/article/pii/S221112472500110X
Jan 2025
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Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.cmet.2024.12.005
  
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sciencedirect.com/science/article/pii/S1550413124004881
Aug 2024
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Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits

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1. scibot 23 Aug 2024
  
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  DOI: 10.1126/sciadv.adn6016
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11338267/
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EDC3 phosphorylation regulates growth and invasion through controlling P‐body formation and dynamics

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1. scibot 02 Aug 2024
  
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  anti‐HIS
  
  DOI: 10.15252/embr.202050835
  
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embopress.org/doi/full/10.15252/embr.202050835
Mar 2024
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Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.molcel.2024.02.006
  
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sciencedirect.com/science/article/pii/S1097276524001254
Feb 2024
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Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection

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1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113845
  
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sciencedirect.com/science/article/pii/S2211124724001736
Dec 2023
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An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.009
  
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sciencedirect.com/science/article/pii/S0092867423012266
Oct 2023
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Typhoid toxin hijacks Wnt5a to establish host senescence and Salmonella infection

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113181
  
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sciencedirect.com/science/article/pii/S2211124723011932
Jun 2023
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Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.cmet.2023.05.009
  
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sciencedirect.com/science/article/pii/S1550413123001869
Jan 2023
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SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

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1. scibot 07 Jan 2023
  
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  DOI: 10.1158/2159-8290.CD-21-0205
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437563/
Jul 2022
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Mutations of 1p genes do not consistently abrogate tumor suppressor functions in 1p-intact neuroblastoma

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1. scibot 01 Jul 2022
  
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  DOI: 10.1186/s12885-022-09800-0
  
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link.springer.com/article/10.1186/s12885-022-09800-0
Sep 2021
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Lrp1 is a host entry factor for Rift Valley fever virus

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1. scibot 24 Sep 2021
  
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  2365
  
  DOI: 10.1016/j.cell.2021.09.001
  
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sciencedirect.com/science/article/pii/S0092867421010485
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Reading ADP-ribosylation signaling using chemical biology and interaction proteomics

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1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.08.037
  
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sciencedirect.com/science/article/pii/S1097276521007176
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Connected neurons in multiple neocortical areas, comprising parallel circuits, encode essential information for visual shape learning

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1. scibot 08 Sep 2021
  
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  RRID:AB_10691695
  
  DOI: 10.1016/j.jchemneu.2021.102024
  
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sciencedirect.com/science/article/pii/S0891061821001071
Apr 2021
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Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation

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1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.10.002
  
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sciencedirect.com/science/article/pii/S1550413120305350
Feb 2021
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CARM1 regulates replication fork speed and stress response by stimulating PARP1

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1. scibot 28 Feb 2021
  
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  DOI: 10.1016/j.molcel.2020.12.010
  
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sciencedirect.com/science/article/pii/S1097276520309023
Sep 2020
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Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.ccell.2020.02.003
  
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sciencedirect.com/science/article/pii/S1535610820300921
Jan 2020
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SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.07.040
  
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sciencedirect.com/science/article/pii/S2211124719309374
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Vaccinia‐related kinase 2 modulates role of dysbindin by regulating protein stability

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1. scibot 13 Jan 2020
  
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  DOI: 10.1111/jnc.14562
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14562
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Untitled document

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  DOI: 10.1016/j.cell.2019.01.037
  
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sciencedirect.com/science/article/pii/S009286741930100X
Nov 2018
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A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276517309826