Hypothesis

19 Matching Annotations

Apr 2026
www.sciencedirect.com www.sciencedirect.com

BCAT1-dependent HIF-1α stabilization is a targetable metabolic vulnerability in hepatocellular carcinoma

1
1. scibot 30 Apr 2026
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.xcrm.2026.102784
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379126002016
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Cortical astrocytic neogenin, a key protein switching HIF1/2ɑ-VEGFa-induced angiogenesis to MEGF10-driven phagocytosis

1
1. scibot 17 Mar 2026
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2026.117071
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472600149X
Mar 2025
www.sciencedirect.com www.sciencedirect.com

The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis

1
1. scibot 11 Mar 2025
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2025.115403
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725001743
Dec 2024
www.cell.com www.cell.com

Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease

1
1. scibot 21 Dec 2024
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.chom.2024.11.012
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

cell.com/cell-host-microbe/fulltext/S1931-3128(24)00443-8
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Metabolic disruption exacerbates intestinal damage during sleep deprivation by abolishing HIF1α-mediated repair

1
1. scibot 20 Nov 2024
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2024.114915
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472401266X
Sep 2024
www.sciencedirect.com www.sciencedirect.com

A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein

1
1. scibot 13 Sep 2024
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2024.114727
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724010787
Aug 2024
www.sciencedirect.com www.sciencedirect.com

A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer

1
1. scibot 22 Aug 2024
  
  in Public
  
  AB_2116958
  
  DOI: 10.1016/j.celrep.2024.114633
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724009835
Apr 2024
www.embopress.org www.embopress.org

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

2
1. scibot 23 Apr 2024
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1038/s44318-024-00065-w
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
2. scibot 23 Apr 2024
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1038/s44318-024-00065-w
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

embopress.org/doi/10.1038/s44318-024-00065-w
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

1
1. scibot 19 Apr 2024
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1038/s44318-024-00065-w
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
Aug 2023
www.sciencedirect.com www.sciencedirect.com

DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

1
1. scibot 03 Aug 2023
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2023.112927
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723009385
Jan 2023
www.sciencedirect.com www.sciencedirect.com

GOT1 regulates CD8+ effector and memory T cell generation

1
1. scibot 19 Jan 2023
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2022.111987
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722018915
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Thiamine insufficiency induces Hypoxia Inducible Factor-1α as an upstream mediator for neurotoxicity and AD-like pathology

1
1. scibot 13 Oct 2022
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.mcn.2022.103785
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1044743122000914
Aug 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells

1
1. scibot 11 Aug 2021
  
  in Public
  
  3434S
  
  DOI: 10.1002/jcb.30126
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2116958
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_2116958

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jcb.30126
academic.oup.com academic.oup.com

Genomic Function of Estrogen Receptor Beta In Endometriosis

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1210/en.2019-00442
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2116958

Annotators

scibot

URL

academic.oup.com/endo/article/160/11/2495/5554111
Jul 2021
www.sciencedirect.com www.sciencedirect.com

lncRNA XIST attenuates hypoxia-induced H9c2 cardiomyocyte injury by targeting the miR-122-5p/FOXP2 axis

1
1. scibot 31 Jul 2021
  
  in Public
  
  HIF-1α
  
  DOI: 10.1016/j.mcp.2019.101500
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0890850819304153
Jun 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1158/2159-8290.CD-20-1353
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958
Visit annotations in context

Tags

RRID:AB_2116958

Annotators

scibot

URL

cancerdiscovery.aacrjournals.org/content/11/6/1398
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.molcel.2020.01.009
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2116958
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276520300095
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Metabolic Rewiring in Response to Biguanides Is Mediated by mROS/HIF-1a in Malignant Lymphocytes

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2116958
  
  DOI: 10.1016/j.celrep.2019.11.007
  
  Resource: (Cell Signaling Technology Cat# 3434, RRID:AB_2116958)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2116958
  
  What is this?
  
  RRID:AB_2116958 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2116958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719314780