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Targeting SMC3 deacetylation synergizes with XPO1 inhibition to reprogram the epigenetic landscape and suppress NPM1-mutated acute myeloid leukemia

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1. scibot 30 Jul 2026
  
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  DOI: 10.1038/s41467-026-74343-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13408497/
Jul 2026
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HDAC5 depletion promotes hyper-acetylation of FOXA1 and potentiates HIF1α transcriptional activation in pancreatic cancer

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1. scibot 10 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.06.022
  
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sciencedirect.com/science/article/pii/S1097276526004119
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110144
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
Mar 2024
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Securin acetylation prevents precocious separase activation and premature sister chromatid separation

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.cub.2024.02.038
  
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2. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.cub.2024.02.038
  
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sciencedirect.com/science/article/pii/S0960982224001805
Feb 2024
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Sphingolipid metabolism controls mammalian heart regeneration

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1. scibot 21 Feb 2024
  
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  DOI: 10.1016/j.cmet.2024.01.017
  
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sciencedirect.com/science/article/pii/S1550413124000172
Jan 2024
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High Glucose Impairs Cognitive Function through Inducing Mitochondrial Calcium Overload in Treg Cells

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1. scibot 18 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108689
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788441/
Nov 2023
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E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

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1. scibot 22 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113477
  
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sciencedirect.com/science/article/pii/S2211124723014894
www.embopress.org www.embopress.org

MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

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1. scibot 03 Nov 2023
  
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  DOI: 10.15252/embj.2023114558
  
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embopress.org/doi/full/10.15252/embj.2023114558
Jul 2023
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GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner

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1. scibot 18 Jul 2023
  
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  DOI: 10.15252/embr.202256437
  
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52.53.155.43/82562d81b2014f2e2d5c134f5e9ab42cec01f29a/embr.202256437-html.html
Jun 2023
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ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112654
  
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sciencedirect.com/science/article/pii/S2211124723006654
Jul 2022
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Acetylation of p62 regulates base excision repair through interaction with APE1

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111116
  
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sciencedirect.com/science/article/pii/S2211124722009226
Mar 2022
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Targeting HNRNPM inhibits cancer stemness and enhances antitumor immunity in Wnt-activated hepatocellular carcinoma

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1. scibot 24 Mar 2022
  
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  DOI: 10.1016/j.jcmgh.2022.02.006
  
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sciencedirect.com/science/article/pii/S2352345X22000339
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Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex

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1. scibot 09 Mar 2022
  
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  RRID:AB_2118062
  
  DOI: 10.1016/j.celrep.2022.110478
  
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sciencedirect.com/science/article/pii/S221112472200211X