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    ER-stress in mouse serotonin neurons triggers a depressive phenotype alleviated by ketamine targeting eIF2α signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11070602/
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    sciencedirect.com/science/article/pii/S1550413124001347
  4. May 2024
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    BPS Publications
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    1. scibot 03 May 2024
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  6. Apr 2024
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    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    Caffeic acid does not protect human pancreatic β cells against stearic acid-induced ER stress and apoptosis
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    onlinelibrary.wiley.com/doi/full/10.1002/ejlt.202300206
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    Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis
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      DOI: 10.1111/jnc.16114

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16114
  10. Mar 2024
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    Brucella-driven host N-glycome remodeling controls infection
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    sciencedirect.com/science/article/pii/S1931312824000830
  12. Feb 2024
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    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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  14. Dec 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TXNDC12 inhibits lipid peroxidation and ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690572/
  16. Nov 2023
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    Exploring the role of SWI/SNF complex subunit BAF60c in lipid metabolism and inflammation in fish
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    sciencedirect.com/science/article/pii/S2589004223022848
  19. Oct 2023
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    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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    LINE-1 activation in the cerebellum drives ataxia
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    ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
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      DOI: 10.7554/eLife.85898

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  23. Sep 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
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    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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  26. Aug 2023
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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  28. Jun 2023
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    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
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    sciencedirect.com/science/article/pii/S2589004223011902
  30. May 2023
  31. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
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    academic.oup.com/endo/article/164/4/bqad035/7056674
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    SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
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  33. Apr 2023
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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  35. Mar 2023
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    TUG-891 inhibits neuronal endoplasmic reticulum stress and... : Neural Regeneration Research
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  37. Feb 2023
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    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
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    MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α
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    sciencedirect.com/science/article/pii/S2211124723000773
  40. Jan 2023
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    Valproate reduces retinal ganglion cell apoptosis in rats... : Neural Regeneration Research
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  42. Dec 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
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  45. Nov 2022
  46. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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  47. Sep 2022
  48. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012566
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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    sciencedirect.com/science/article/pii/S1535610822003804
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endoplasmic reticulum stress induces Alzheimer's disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein
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      DOI: 10.1111/jnc.15687

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15687
  51. Jun 2022
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    Age-related endoplasmic reticulum stress represses testosterone synthesis via attenuation of the circadian clock in Leydig cells
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    sciencedirect.com/science/article/pii/S0093691X22002357
  53. Apr 2022
  54. www.sciencedirect.com www.sciencedirect.com
    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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    sciencedirect.com/science/article/pii/S1534580722002064
  55. Mar 2022
  56. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101555RR
  57. rupress.org rupress.org
    PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen
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      DOI: 10.1084/jem.20211498

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    rupress.org/jem/article/219/4/e20211498/213062/PERK-reprograms-hematopoietic-progenitor-cells-to
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    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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      DOI: 10.1016/j.celrep.2022.110509

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    sciencedirect.com/science/article/pii/S2211124722002455
  59. Feb 2022
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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    onlinelibrary.wiley.com/doi/10.1002/ddr.21916
  61. Jan 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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      DOI: 10.3233/ADR-210050

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    ncbi.nlm.nih.gov/pmc/articles/PMC8764631/
  63. Nov 2021
  64. academic.oup.com academic.oup.com
    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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      DOI: 10.1016/j.molcel.2019.01.036

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    TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
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      DOI: 10.1016/j.molcel.2019.03.034

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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      DOI: 10.1016/j.ccell.2019.01.006

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  120. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death
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    Systematic Characterization of Stress-Induced RNA Granulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC5791736/
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    CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
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      Curator: @evieth

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    Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity
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