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Aug 2025
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β Cell Gαs signaling is critical for physiological and pharmacological enhancement of insulin secretion

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pmc.ncbi.nlm.nih.gov/articles/PMC12352888/
Jul 2025
52.53.155.43 52.53.155.43

Dysregulation of cholesterol homeostasis is an early signal of beta cell proteotoxicity characteristic of type 2 diabetes. | Physiological Genomics

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52.53.155.43/4aa0aab79be754d8aad9e89a1a3949e58de2b850/gurlo-et-al-2024-dysregulation-of-cholesterol-homeostasis-is-an-early-signal-of--cell-proteotoxicity-characteristic-of-html.html
journals.physiology.org journals.physiology.org

Dysregulation of cholesterol homeostasis is an early signal of beta cell proteotoxicity characteristic of type 2 diabetes.

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journals.physiology.org/doi/10.1152/physiolgenomics.00029.2024
May 2025
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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice

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Feb 2025
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A comprehensive atlas of AAV tropism in the mouse

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Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

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Nov 2024
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Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions

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  DOI: 10.1021/acsnano.3c09206
  
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Core circadian transcription factor Bmal1 mediates β cell response and recovery from pro-inflammatory injury

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pmc.ncbi.nlm.nih.gov/articles/PMC11550590/
Sep 2024
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A Comprehensive Atlas of AAV Tropism in the Mouse

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  DOI: 10.1101/2024.09.10.612279
  
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biorxiv.org/content/10.1101/2024.09.10.612279v1
Aug 2024
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Supplemental materials - Endocrinology - Feb2022 - compressed2-html.html

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52.53.155.43/72ed490738a0b3974682e1150ef193d1e2bb6e07/Supplemental materials - Endocrinology - Feb2022 - compressed2-html.html
May 2024
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Chronic intermittent fasting impairs β-cell maturation and function in adolescent mice

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1. scibot 03 May 2024
  
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  DOI: 10.1101/2024.04.18.590140
  
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biorxiv.org/content/10.1101/2024.04.18.590140v1
Sep 2023
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Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

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1. scibot 08 Sep 2023
  
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  DOI: 10.7554/eLife.90006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
Aug 2023
52.53.155.43 52.53.155.43

Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112914
  
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52.53.155.43/464fcb14db36fa0ad68672734eea21dbff7f105c/PIIS2211124723009257-html.html
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SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells

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  DOI: 10.1007/s00125-023-05979-4
  
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link.springer.com/article/10.1007/s00125-023-05979-4
Jul 2023
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AAV5-mediated manipulation of insulin expression in choroid plexus has long-term metabolic and behavioral consequences

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  DOI: 10.1016/j.celrep.2023.112903
  
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sciencedirect.com/science/article/pii/S2211124723009142
Mar 2023
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Protocol for in vivo and ex vivo assessment of hyperglycemia and islet function in diabetic mice

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  DOI: 10.1016/j.xpro.2023.102133
  
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sciencedirect.com/science/article/pii/S2666166723000916
Jan 2023
diabetesjournals.org diabetesjournals.org

GC-globulin/vitamin D-binding protein is Required for Pancreatic α Cell Adaptation to Metabolic Stress

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diabetesjournals.org/diabetes/article/72/2/275/147957/GC-Globulin-Vitamin-D-Binding-Protein-Is-Required
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ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance

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ncbi.nlm.nih.gov/pmc/articles/PMC9840936/
Nov 2022
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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma

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sciencedirect.com/science/article/pii/S2211124722014942
Aug 2022
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GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming

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sciencedirect.com/science/article/pii/S2352345X22001552
Jun 2022
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SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis

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  DOI: 10.1016/j.isci.2022.104594
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9212970/
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IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells

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  DOI: 10.1016/j.devcel.2022.05.013
  
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sciencedirect.com/science/article/pii/S1534580722003707
Feb 2022
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Novel Pathogenic de novo INS p.T97P Variant Presenting with Severe Neonatal DKA

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  DOI: 10.1210/endocr/bqab246
  
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academic.oup.com/endo/article/163/2/bqab246/6458485
Jan 2022
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Developmental Timing of High Fat Diet Exposure Impacts Glucose Homeostasis in Mice in a Sex-Specific Manner

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ncbi.nlm.nih.gov/pmc/articles/PMC8660987/
Dec 2021
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Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes

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sciencedirect.com/science/article/pii/S193459092100415X
Nov 2021
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Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice

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  DOI: 10.1016/j.xcrm.2021.100434
  
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sciencedirect.com/science/article/pii/S2666379121002962
Jul 2021
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Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats

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  DOI: 10.1038/s41598-021-93409-z
  
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nature.com/articles/s41598-021-93409-z
May 2021
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Prolonged Low-Dose Dioxin Exposure Impairs Metabolic Adaptability to High-Fat Diet Feeding in Female but Not Male Mice

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  DOI: 10.1210/endocr/bqab050
  
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academic.oup.com/endo/article/162/6/bqab050/6161518
Feb 2021
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PDX1 LOW MAFA LOW β-cells contribute to islet function and insulin release

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  DOI: 10.1038/s41467-020-20632-z
  
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  DOI: 10.1038/s41467-020-20632-z
  
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nature.com/articles/s41467-020-20632-z
Jan 2021
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Protocol for determining zinc-dependent β cell-selective small-molecule delivery in mouse pancreas

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1. scibot 22 Jan 2021
  
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  Rabbit insulin (C27C9) 1° antibody
  
  DOI: 10.1016/j.xpro.2020.100263
  
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sciencedirect.com/science/article/pii/S2666166720302501
Sep 2020
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Generation of an INSULIN-H2B-Cherry reporter human iPSC line

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  DOI: 10.1016/j.scr.2020.101797
  
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Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion

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  DOI: 10.1016/j.celrep.2020.107761
  
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sciencedirect.com/science/article/pii/S2211124720307415
Jan 2020
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Untitled document

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  DOI: 10.1016/j.cmet.2018.11.014
  
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Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells

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Local Integrin Activation in Pancreatic β Cells Targets Insulin Secretion to the Vasculature

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Untitled document

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Insulin deficient mouse β-cells do not fully mature but can be remedied through insulin replacement by islet transplantation

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Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

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Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity

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Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes

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