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A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinoma

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102622
  
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sciencedirect.com/science/article/pii/S266637912600039X
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Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.cell.2025.12.053
  
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sciencedirect.com/science/article/pii/S0092867425015028
Nov 2025
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Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis

1
1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116620
  
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sciencedirect.com:5037/science/article/pii/S2211124725013920
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma

1
1. scibot 08 Nov 2025
  
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  AB_2133513
  
  DOI: 10.1158/1078-0432.CCR-20-0018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8440125/
Sep 2025
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Recycling endosomes in mature epithelia restrain tumorigenic signaling

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1. scibot 07 Sep 2025
  
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  DOI: 10.1158/0008-5472.CAN-18-4075
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6726494/
Aug 2025
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Mechanical signaling via β2 integrin decouples T cell proliferation and differentiation for generating stem cell-like CAR T cells

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1. scibot 09 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.018
  
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sciencedirect.com/science/article/pii/S1074761325003279
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BPS Publications

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1. scibot 01 Aug 2025
  
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  RRID:AB_2133513
  
  DOI: 10.1111/bph.70137
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70137
Jul 2025
dx.doi.org dx.doi.org

The planar cell polarity (PCP) protein Fat 1 in Sertoli cell function

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1. scibot 02 Jul 2025
  
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  DOI: 10.1210/endocr/bqae041
  
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dx.doi.org/10.1210/endocr/bqae041
Jun 2025
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RIPK4 promotes epidermal differentiation through phase separation and activation of LATS1/2

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.devcel.2025.05.017
  
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sciencedirect.com/science/article/pii/S1534580725003284
Sep 2024
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CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110832
  
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sciencedirect.com/science/article/pii/S2589004224020571
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PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.009
  
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sciencedirect.com/science/article/pii/S1550413124003619
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Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer

1
1. scibot 13 Sep 2024
  
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  DOI: 10.1038/s41467-024-51831-7
  
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nature.com/articles/s41467-024-51831-7
Aug 2024
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SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation

1
1. scibot 02 Aug 2024
  
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  LATS1
  
  DOI: 10.1007/s00395-021-00865-9
  
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link.springer.com/article/10.1007/s00395-021-00865-9/tables/2
Jul 2024
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Amphiregulin orchestrates the paracrine immune-suppressive function of amniotic-derived cells through its interplay with COX-2/PGE2/EP4 axis

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1. scibot 26 Jul 2024
  
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  AB_2133513
  
  DOI: 10.1016/j.isci.2024.110508
  
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sciencedirect.com/science/article/pii/S2589004224017334
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress

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1. scibot 03 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.109983
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
Mar 2024
www.cell.com www.cell.com

Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.

3
1. scibot 07 Mar 2024
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2024.109146
  
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2. scibot 07 Mar 2024
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2024.109146
  
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3. scibot 02 Mar 2024
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2024.109146
  
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cell.com/iscience/abstract/S2589-0042(24)00367-5
Feb 2024
52.53.155.43 52.53.155.43

YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

1
1. scibot 09 Feb 2024
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2024.109125
  
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52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway

1
1. scibot 01 Dec 2023
  
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  AB_2133513
  
  DOI: 10.1038/s41419-023-06312-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
Aug 2023
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The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

1
1. scibot 05 Aug 2023
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2023.107449
  
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sciencedirect.com/science/article/pii/S2589004223015262
Jul 2023
www.nature.com www.nature.com

MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice

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1. scibot 14 Jul 2023
  
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  RRID:AB_2133513
  
  DOI: 10.1038/s41536-023-00310-6
  
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nature.com/articles/s41536-023-00310-6
Apr 2023
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Regulation of sertoli cell function by planar cell polarity (PCP) protein Fjx1

1
1. scibot 29 Apr 2023
  
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  AB_2133513
  
  DOI: 10.1016/j.mce.2023.111936
  
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sciencedirect.com/science/article/pii/S0303720723000874
Mar 2023
www.embopress.org www.embopress.org

Two Hippo signaling modules orchestrate liver size and tumorigenesis

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1. scibot 16 Mar 2023
  
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  DOI: 10.15252/embj.2022112126
  
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2. scibot 16 Mar 2023
  
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  RRID:AB_2133513
  
  DOI: 10.15252/embj.2022112126
  
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embopress.org/doi/10.15252/embj.2022112126
Dec 2022
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Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning

1
1. scibot 08 Dec 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.celrep.2022.111766
  
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sciencedirect.com/science/article/pii/S2211124722016497
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.

1
1. scibot 27 Oct 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2022.105275
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9589172/
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Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer

1
1. scibot 05 Oct 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.celrep.2022.111443
  
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sciencedirect.com/science/article/pii/S2211124722012840
Sep 2022
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A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

1
1. scibot 29 Sep 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.celrep.2022.111412
  
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sciencedirect.com/science/article/pii/S2211124722012530
Aug 2022
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Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers

1
1. scibot 31 Aug 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.celrep.2022.111296
  
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sciencedirect.com/science/article/pii/S2211124722011160
Jun 2022
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The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin

1
1. scibot 15 Jun 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1186/s12964-022-00843-1
  
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link.springer.com/article/10.1186/s12964-022-00843-1
May 2022
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JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation

1
1. scibot 13 May 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.isci.2022.104316
  
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sciencedirect.com/science/article/pii/S2589004222005879
www.cell.com www.cell.com

Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

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1. scibot 05 May 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.cell.2022.04.014
  
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cell.com/cell/fulltext/S0092-8674(22)00461-5
Apr 2022
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

1
1. scibot 20 Apr 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.molcel.2022.03.027
  
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sciencedirect.com/science/article/pii/S1097276522002659
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist

1
1. scibot 11 Mar 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1038/s41598-022-07600-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
Feb 2022
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Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction

1
1. scibot 16 Feb 2022
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.celrep.2022.110390
  
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sciencedirect.com/science/article/pii/S2211124722001115
Oct 2021
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Glycogen accumulation and phase separation drives liver tumor initiation

1
1. scibot 22 Oct 2021
  
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  RRID:AB_2133513
  
  DOI: 10.1016/j.cell.2021.10.001
  
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Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

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Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis

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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

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S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation

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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

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A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis

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Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation

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A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling

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Recycling endosomes in mature epithelia restrain tumorigenic signaling

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mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury

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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

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Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1

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CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity

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OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

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FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis

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Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction

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The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection

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SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis

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Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

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YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis

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Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

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Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance

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