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  1. Last 7 days
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    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
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    PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders
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  4. Sep 2024
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    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  6. Aug 2024
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    SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation
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    link.springer.com/article/10.1007/s00395-021-00865-9/tables/2
  8. Jul 2024
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    Amphiregulin orchestrates the paracrine immune-suppressive function of amniotic-derived cells through its interplay with COX-2/PGE2/EP4 axis
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  10. Jun 2024
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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  12. Mar 2024
  13. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  14. Feb 2024
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    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
  18. Aug 2023
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    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
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    sciencedirect.com/science/article/pii/S2589004223015262
  20. Jul 2023
  21. www.nature.com www.nature.com
    MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
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    nature.com/articles/s41536-023-00310-6
  22. Apr 2023
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    Regulation of sertoli cell function by planar cell polarity (PCP) protein Fjx1
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    sciencedirect.com/science/article/pii/S0303720723000874
  24. Mar 2023
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    Two Hippo signaling modules orchestrate liver size and tumorigenesis
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    embopress.org/doi/10.15252/embj.2022112126
  26. Dec 2022
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    Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning
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    sciencedirect.com/science/article/pii/S2211124722016497
  28. Oct 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.
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    ncbi.nlm.nih.gov/pmc/articles/PMC9589172/
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    Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer
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    sciencedirect.com/science/article/pii/S2211124722012840
  31. Sep 2022
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    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
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  33. Aug 2022
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    sciencedirect.com/science/article/pii/S2211124722011160
  35. Jun 2022
  36. link.springer.com link.springer.com
    The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin
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      RRID:AB_2133513

      DOI: 10.1186/s12964-022-00843-1

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  37. May 2022
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    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
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    sciencedirect.com/science/article/pii/S2589004222005879
  39. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  40. Apr 2022
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    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  42. Mar 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
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      DOI: 10.1038/s41598-022-07600-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
  44. Feb 2022
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    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
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    sciencedirect.com/science/article/pii/S2211124722001115
  46. Oct 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Glycogen accumulation and phase separation drives liver tumor initiation
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    sciencedirect.com/science/article/pii/S0092867421011752
  48. Aug 2021
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    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    sciencedirect.com/science/article/pii/S1097276521006249
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    Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124721010342
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    Untitled document
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      DOI: 10.1016/j.ccell.2018.11.006

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    sciencedirect.com/science/article/pii/S1535610818305270
  52. Jul 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.cub.2018.11.066

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    ncbi.nlm.nih.gov/pmc/articles/PMC6345631/
  54. May 2021
  55. www.sciencedirect.com www.sciencedirect.com
    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
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    sciencedirect.com/science/article/pii/S1097276521003142
  56. Mar 2021
  57. www.sciencedirect.com www.sciencedirect.com
    S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
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      DOI: 10.1016/j.chembiol.2021.01.004

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    sciencedirect.com/science/article/pii/S2451945621000040
  58. Dec 2020
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
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      DOI: 10.1016/j.molcel.2020.11.028

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    ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
  60. Oct 2020
  61. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
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      DOI: 10.1016/j.celrep.2020.108284

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    sciencedirect.com/science/article/pii/S2211124720312730
  62. Sep 2020
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration
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      DOI: 10.7554/eLife.55771

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    ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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      DOI: 10.1016/j.ccell.2019.12.006

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    sciencedirect.com/science/article/pii/S1535610819305768
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    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
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      DOI: 10.1016/j.celrep.2020.107860

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    sciencedirect.com/science/article/pii/S221112472030841X
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    A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling
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      DOI: 10.1016/j.celrep.2020.108118

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    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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      DOI: 10.1158/0008-5472.CAN-18-4075

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    ncbi.nlm.nih.gov/pmc/articles/PMC6726494/
  68. www.sciencedirect.com www.sciencedirect.com
    mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury
    1
    1. scibot 08 Sep 2020
      RRID:AB_2133513

      DOI: 10.1016/j.immuni.2020.02.002

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    sciencedirect.com/science/article/pii/S107476132030073X
  69. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
    1
    1. scibot 06 Sep 2020
      RRID:AB_2133513

      DOI: 10.1016/j.cmet.2020.03.010

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    sciencedirect.com/science/article/pii/S155041312030125X
  70. Jan 2020
  71. www.sciencedirect.com www.sciencedirect.com
    Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1
    1
    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.celrep.2019.11.035

      Resource: (Cell Signaling Technology Cat# 3477, RRID:AB_2133513)

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719315177
  72. elifesciences.org elifesciences.org
    CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.7554/eLife.46012

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      RRID:AB_2133513 RRIDCUR:Validated
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    elifesciences.org/articles/46012
  73. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.cub.2018.11.066

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0960982218315963
  74. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.ccell.2019.01.009

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    sciencedirect.com/science/article/pii/S1535610819300431
  75. www.sciencedirect.com www.sciencedirect.com
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    1
    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.devcel.2019.04.018

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580719302990
  76. www.sciencedirect.com www.sciencedirect.com
    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
    1
    1. scibot 12 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.molcel.2018.10.030

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518308906
  77. www.sciencedirect.com www.sciencedirect.com
    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
    1
    1. scibot 12 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.devcel.2018.12.021

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580718311171
  78. Nov 2018
  79. www.sciencedirect.com www.sciencedirect.com
    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
    1
    1. scibot 05 Nov 2018
      RRID:AB_2133513

      Curator: @Jmenke

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518306981
  80. www.sciencedirect.com www.sciencedirect.com
    The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection
    1
    1. scibot 05 Nov 2018
      RRID:AB_2133513

      Curator: @Jmenke

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1931312818304323
  81. www.sciencedirect.com www.sciencedirect.com
    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
    1
    1. scibot 05 Nov 2018
      RRID:AB_2133513

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      (Cell Signaling Technology Cat# 3477, RRID:AB_2133513)

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      RRID:AB_2133513
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    sciencedirect.com/science/article/pii/S1535610818302307
  82. www.sciencedirect.com www.sciencedirect.com
    Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores
    1
    1. scibot 05 Nov 2018
      RRID:AB_2133513

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      RRID:AB_2133513
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    sciencedirect.com/science/article/pii/S0092867417311923
  83. Nov 2017
  84. www.sciencedirect.com www.sciencedirect.com
    The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
    1
    1. scibot 08 Nov 2017
      3477

      Curator: @Jmenke

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      RRID:AB_2133513 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416315264
  85. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
    1
    1. scibot 08 Nov 2017
      RRID:AB_2133513

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 3477, RRID:AB_2133513)

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717306305
  86. www.sciencedirect.com www.sciencedirect.com
    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
    1
    1. scibot 08 Nov 2017
      AB_2133513

      Curator: @kaitlinsung

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      (Cell Signaling Technology Cat# 3477, RRID:AB_2133513)

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817301599
  87. www.sciencedirect.com www.sciencedirect.com
    Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
    1
    1. scibot 08 Nov 2017
      AB_2133513

      Curator: @kaitlinsung

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      (Cell Signaling Technology Cat# 3477, RRID:AB_2133513)

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      RRID:AB_2133513 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717301156