Hypothesis

33 Matching Annotations

Last 7 days
54.241.53.176 54.241.53.176

A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

1
1. scibot 23 Dec 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.64898/2025.12.18.695023
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

54.241.53.176/4017c0bf441a0c93b25bb7d3207bac083a93d59a/2025.12.18.695023v1.full-html.html
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis

1
1. scibot 05 Dec 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.3389/fonc.2025.1671797
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12672324/
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Obesity induced by a high-fat diet regulates the MYC‒PPIL1 network in the mediation of asthenozoospermia

1
1. scibot 14 Oct 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1186/s12610-025-00289-8
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12512847/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer

1
1. scibot 24 Sep 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.cmet.2025.08.009
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413125003821
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex

1
1. scibot 06 Aug 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.molcel.2025.07.007
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525006082
Jun 2025
www.sciencedirect.com www.sciencedirect.com

PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity

1
1. scibot 05 Jun 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.celrep.2025.115785
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472500556X
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225008958-main-html.html

1
1. scibot 18 May 2025
  
  in Public
  
  AB_2148585
  
  DOI: 10.1016/j.isci.2025.112634
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

52.53.155.43/3124e289592a3629f97e02aa5117cdb2659dc765/1-s2.0-S2589004225008958-main-html.html
Apr 2025
link.springer.com link.springer.com

LINC02167 stabilizes KSR1 mRNA in an m5C-dependent manner to regulate the ERK/MAPK signaling pathway and promotes colorectal cancer metastasis

1
1. scibot 17 Apr 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1186/s13046-025-03368-w
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

link.springer.com/article/10.1186/s13046-025-03368-w
www.cell.com www.cell.com

PRMT5-mediated methylation of METTL3 promotes cisplatin resistance in ovarian cancer by facilitating DNA repair mechanisms

1
1. scibot 02 Apr 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.celrep.2025.115484
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(25)00255-4
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

1
1. scibot 27 Mar 2025
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.7554/eLife.101973
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.molcel.2024.10.046
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524008852
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis

1
1. scibot 21 Nov 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.isci.2024.111214
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11574807/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

A TBK1-independent primordial function of STING in lysosomal biogenesis

1
1. scibot 25 Sep 2024
  
  in Public
  
  AB_2148585
  
  DOI: 10.1016/j.molcel.2024.08.026
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524007032
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT

1
1. scibot 21 Aug 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1186/s40170-024-00352-4
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11304919/
52.53.155.43 52.53.155.43

FEBS Press

1
1. scibot 02 Aug 2024
  
  in Public
  
  RRID: AB_2148585
  
  DOI: 10.1111/febs.16877
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

52.53.155.43/64ced1d526c8a3e3d4ab74d77899078a022462a0/The FEBS Journal - 2023 - Shan - Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing-html.html
academic.oup.com academic.oup.com

Targeting tumor hypoxia inhibits aggressive phenotype of dedifferentiated thyroid cancer

1
1. scibot 02 Aug 2024
  
  in Public
  
  RRID: AB_2148585
  
  DOI: 10.1210/clinem/dgac548
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgac548/6747527
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation

1
1. scibot 24 Jul 2024
  
  in Public
  
  AB_2148585
  
  DOI: 10.1016/j.cmet.2024.05.016
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041312400192X
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Repurposing AS1411 for constructing ANM-PROTACs

1
1. scibot 24 Apr 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.chembiol.2024.03.011
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945624001272
www.sciencedirect.com www.sciencedirect.com

Genetic interactions reveal distinct biological and therapeutic implications in breast cancer

1
1. scibot 09 Apr 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.ccell.2024.03.006
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610824000916
Mar 2024
www.sciencedirect.com www.sciencedirect.com

A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice

1
1. scibot 13 Mar 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.molcel.2024.02.019
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524001382
Feb 2024
www.sciencedirect.com www.sciencedirect.com

A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

1
1. scibot 29 Feb 2024
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.molcel.2024.02.002
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524000984
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer

1
1. scibot 20 Sep 2023
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1158/0008-5472.CAN-23-0067
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10502452/
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner

1
1. scibot 06 Sep 2023
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1096/fj.202202145RRR
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202145RRR
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness

2
1. scibot 21 Jul 2023
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1038/s41392-023-01487-4
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
2. scibot 21 Jul 2023
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1038/s41392-023-01487-4
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
52.53.155.43 52.53.155.43

can-23-0067-html.html

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1158/0008-5472.can-23-0067
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

52.53.155.43/1af2a0d742419295c56fc417c605df7b31cfe676/can-23-0067-html.html
Jun 2023
52.53.155.43 52.53.155.43

FEBS Press

1
1. scibot 03 Jun 2023
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1111/febs.16877
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

52.53.155.43/64ced1d526c8a3e3d4ab74d77899078a022462a0/The FEBS Journal - 2023 - Shan - Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing-html.html
Oct 2022
academic.oup.com academic.oup.com

Targeting tumor hypoxia inhibits aggressive phenotype of dedifferentiated thyroid cancer

1
1. scibot 29 Oct 2022
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1210/clinem/dgac548
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgac548/6747527
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration

1
1. scibot 02 Oct 2022
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.isci.2022.105050
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9519511/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Efferocytosis induces macrophage proliferation to help resolve tissue injury

1
1. scibot 16 Nov 2021
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.cmet.2021.10.015
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413121005271
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Cancer cell immune mimicry delineates onco-immunologic modulation

1
1. scibot 11 Oct 2021
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.isci.2021.103133
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585
Visit annotations in context

Tags

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004221011019
Jan 2020
www.sciencedirect.com www.sciencedirect.com

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819300406
www.sciencedirect.com www.sciencedirect.com

MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2148585
  
  DOI: 10.1016/j.ebiom.2019.03.027
  
  Resource: (Proteintech Cat# 10828-1-AP, RRID:AB_2148585)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2148585
  
  What is this?
  
  RRID:AB_2148585 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2148585

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396419301677