71 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Enhanced antitumor immunity in breast cancer: Synergistic effects of ADAM10/ADAM17 inhibition, metabolic modulation, and camptothecin-loaded selenium nanoparticles
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    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.ijpharm.2024.125037

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    sciencedirect.com/science/article/pii/S0378517324012717
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic inhibition of eIF4A blocks NRF2 synthesis to prevent osteosarcoma metastasis
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    1. scibot 04 Oct 2024
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      DOI: 10.1158/1078-0432.CCR-24-1317

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443218/
  5. Aug 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC
    1
    1. scibot 29 Aug 2024
      RRID:AB_2151827

      DOI: 10.1186/s12964-024-01782-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11348570/
  7. Jul 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal changes in Netrin/Dscam1 signaling dictate axonal projection direction in Drosophila small ventral lateral clock neurons
    1
    1. scibot 27 Jul 2024
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      DOI: 10.7554/eLife.96041

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    ncbi.nlm.nih.gov/pmc/articles/PMC11272162/
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.cmet.2024.04.018

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    sciencedirect.com/science/article/pii/S1550413124001384
  11. www.sciencedirect.com www.sciencedirect.com
    linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
    1
    1. scibot 16 May 2024
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      DOI: 10.1016/j.celrep.2024.114240

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    sciencedirect.com/science/article/pii/S2211124724005680
  12. Mar 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.isci.2024.109417

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    ncbi.nlm.nih.gov/pmc/articles/PMC10952034/
  14. Feb 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
    1
    1. scibot 21 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0379

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    ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
  16. www.cell.com www.cell.com
    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.004

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    cell.com/cell/fulltext/S0092-8674(24)00006-0
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113629

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    sciencedirect.com/science/article/pii/S2211124723016406
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.isci.2023.108659

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    sciencedirect.com/science/article/pii/S2589004223027360
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    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
    1
    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108568

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    sciencedirect.com/science/article/pii/S2589004223026457
  22. Nov 2023
  23. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
    1
    1. scibot 25 Nov 2023
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      DOI: 10.1038/s41388-023-02892-3

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    nature.com/articles/s41388-023-02892-3
  24. www.sciencedirect.com www.sciencedirect.com
    Aryl Hydrocarbon Receptor is a Tumor Promoter in MYCN-Amplified Neuroblastoma Cells Through Suppression of Differentiation
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.isci.2023.108303

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    sciencedirect.com/science/article/pii/S2589004223023805
  25. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
    1
    1. scibot 09 Nov 2023
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      DOI: 10.1016/j.molcel.2021.03.010

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    sciencedirect.com/science/article/pii/S1097276521001787
  26. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113354

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    sciencedirect.com/science/article/pii/S2211124723013669
  27. Oct 2023
  28. www.sciencedirect.com www.sciencedirect.com
    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    1
    1. scibot 17 Oct 2023
      RRID:AB_2151827

      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
  29. Sep 2023
  30. www.nature.com www.nature.com
    A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1038/s41467-023-40798-6

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    nature.com/articles/s41467-023-40798-6
  31. Aug 2023
  32. 52.53.155.43 52.53.155.43
    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112961

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112961

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    52.53.155.43/e4339d2342058d0ba733e06b854674a1d2f752a1/PIIS2211124723009725-html.html
  33. Jul 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Orphan quality control shapes network dynamics and gene expression
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.015

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    sciencedirect.com/science/article/pii/S0092867423006918
  35. May 2023
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dihydroartemisinin inhibited stem cell-like properties and enhanced oxaliplatin sensitivity of colorectal cancer via AKT/mTOR signaling
    1
    1. scibot 11 May 2023
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      DOI: 10.1002/ddr.22067

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    onlinelibrary.wiley.com/doi/10.1002/ddr.22067
  37. Apr 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Cellular proteins act as surfactants to control the interfacial behavior and function of biological condensates
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.devcel.2023.04.004

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    sciencedirect.com/science/article/pii/S1534580723001570
  39. Jan 2023
  40. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 14 Jan 2023
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      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  41. Aug 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
    1
    1. scibot 23 Aug 2022
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      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  43. Jul 2022
  44. yc.mlpla.mil.cn yc.mlpla.mil.cn
    Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
    1
    1. scibot 15 Jul 2022
      RRID:AB_2151827

      DOI: 10.1016/j.chembiol.2022.06.007

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    yc.mlpla.mil.cn/s/com/sciencedirect/www/G.https/science/article/pii/S2451945622002392
  45. May 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Interaction Between the Oncogenic Kinase NEK2 and Sam68 Promotes a Splicing Program Involved in Migration and Invasion in Triple-Negative Breast Cancer
    1
    1. scibot 11 May 2022
      AB_2151827

      DOI: 10.3389/fonc.2022.880654

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    ncbi.nlm.nih.gov/pmc/articles/PMC9068942/
  47. Apr 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
    1
    1. scibot 27 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110752

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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  49. Mar 2022
  50. www.sciencedirect.com www.sciencedirect.com
    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
    1
    1. scibot 16 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110511

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    sciencedirect.com/science/article/pii/S2211124722002479
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
    1
    1. scibot 11 Mar 2022
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      DOI: 10.1038/s41598-022-07600-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
  52. Jan 2022
  53. www.sciencedirect.com www.sciencedirect.com
    The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis
    1
    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.molcel.2021.11.017

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    sciencedirect.com/science/article/pii/S1097276521009977
  54. Dec 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
    1
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      DOI: 10.1016/j.celrep.2021.110186

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    sciencedirect.com/science/article/pii/S2211124721016867
  56. academic.oup.com academic.oup.com
    Downregulation Of Dihydrotestosterone And Estradiol Levels By Hexim1
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      DOI: 10.1210/endocr/bqab236

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    academic.oup.com/endo/article/163/1/bqab236/6432009
  57. Oct 2021
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15652

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15652
  59. Sep 2021
  60. www.sciencedirect.com www.sciencedirect.com
    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
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      DOI: 10.1016/j.chembiol.2021.08.004

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    sciencedirect.com/science/article/pii/S2451945621003937
  61. Aug 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
    1
    1. scibot 14 Aug 2021
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      DOI: 10.1016/j.molcel.2019.03.025

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    ncbi.nlm.nih.gov/pmc/articles/PMC6671628/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 10 Aug 2021
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      DOI: 10.1016/j.celrep.2018.12.071

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    ncbi.nlm.nih.gov/pmc/articles/PMC6334229/
  64. www.sciencedirect.com www.sciencedirect.com
    Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers
    1
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      DOI: 10.1016/j.cmet.2018.06.005

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    sciencedirect.com/science/article/pii/S1550413118303875
  65. Jul 2021
  66. mcr.aacrjournals.org mcr.aacrjournals.org
    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
    1
    1. scibot 31 Jul 2021
      c-Myc

      DOI: 10.1158/1541-7786.MCR-19-0747

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  68. www.nature.com www.nature.com
    MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
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  69. Jun 2021
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    Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
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  71. May 2021
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    MYC up-regulation confers resistance to everolimus and establishes vulnerability to cyclin dependent kinase inhibitors in pancreatic neuroendocrine neoplasms cells
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    ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis
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  74. Apr 2021
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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  79. Feb 2021
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    Constitutive androstane receptor induced-hepatomegaly is partially via yes-associated protein activation
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  82. Jan 2021
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    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
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  84. Nov 2020
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  86. Oct 2020
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  88. Sep 2020
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    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
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    Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity
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    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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    Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac
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  94. Jan 2020
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    Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling
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  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression and clinical value of PD‐L1 which is regulated by BRD4 in tongue squamous cell carcinoma
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    Expression of the double‐stranded RNA‐dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion
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    Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
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    Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
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  103. Nov 2018
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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  105. Nov 2017
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    Sam68 Allows Selective Targeting of Human Cancer Stem Cells
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    Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
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    De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones
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