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54.241.53.176 54.241.53.176

A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

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1. scibot 23 Dec 2025
  
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  DOI: 10.64898/2025.12.18.695023
  
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54.241.53.176/4017c0bf441a0c93b25bb7d3207bac083a93d59a/2025.12.18.695023v1.full-html.html
Dec 2025
rupress.org rupress.org

Notch interaction with RUNX factors regulates initiation of the T-lineage program

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1. scibot 11 Dec 2025
  
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  DOI: 10.1084/jem.20250911
  
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rupress.org/jem/article/223/2/e20250911/278551/Notch-interaction-with-RUNX-factors-regulates
Aug 2025
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Design of soluble Notch agonists that drive T cell development and boost immunity

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1. scibot 05 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.009
  
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sciencedirect.com/science/article/pii/S0092867425007986
Jun 2025
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Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.cels.2025.101321
  
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sciencedirect.com/science/article/pii/S2405471225001541
May 2025
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Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.chom.2025.05.004
  
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sciencedirect.com/science/article/pii/S1931312825001830
www.cell.com www.cell.com

Myocardium and endocardium of the early mammalian heart tube arise from independent multipotent lineages specified at the primitive streak

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1. scibot 30 May 2025
  
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  DOI: 10.1016/j.devcel.2025.05.002
  
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cell.com/developmental-cell/fulltext/S1534-5807(25)00292-8
Mar 2025
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Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis

1
1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.009
  
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sciencedirect.com/science/article/pii/S1535610825000613
Feb 2025
elifesciences.org elifesciences.org

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway

1
1. scibot 14 Feb 2025
  
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  DOI: 10.7554/eLife.97268
  
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elifesciences.org/articles/97268
Jan 2025
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Revealing the role of cancer-associated fibroblast senescence in prognosis and immune landscape in pancreatic cancer

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111612
  
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sciencedirect.com/science/article/pii/S2589004224028396
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

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1. scibot 13 Dec 2024
  
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  DOI: 10.1038/s44321-024-00161-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
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Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.stem.2024.10.015
  
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sciencedirect.com/science/article/pii/S1934590924003771
Nov 2024
www.embopress.org www.embopress.org

Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44318-024-00290-3
  
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embopress.org/doi/10.1038/s44318-024-00290-3
52.53.155.43 52.53.155.43

wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html

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1. scibot 14 Nov 2024
  
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  AB_2153348
  
  DOI: 10.1038/s44318-024-00290-3
  
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52.53.155.43/052dd78e8f9f0d46ee449e71fc9d1d608c537305/wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells

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1. scibot 07 Nov 2024
  
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  DOI: 10.3389/fimmu.2024.1470620
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11487346/
Oct 2024
www.embopress.org www.embopress.org

SOX10 mediates glioblastoma cell-state plasticity

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1. scibot 02 Oct 2024
  
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  DOI: 10.1038/s44319-024-00258-8
  
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embopress.org/doi/full/10.1038/s44319-024-00258-8
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway

1
1. scibot 18 Sep 2024
  
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  DOI: 10.7554/eLife.90854
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11390110/
Aug 2024
www.cell.com www.cell.com

Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility

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1. scibot 18 Aug 2024
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.celrep.2024.114582
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00911-2
Jul 2024
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Brain ischemia causes systemic Notch1 activity in endothelial cells to drive atherosclerosis

1
1. scibot 30 Jul 2024
  
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  AB_2153348
  
  DOI: 10.1016/j.immuni.2024.07.002
  
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sciencedirect.com/science/article/pii/S1074761324003510
Jun 2024
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Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.05.013
  
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sciencedirect.com/science/article/pii/S155041312400189X
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Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation

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1. scibot 21 Jun 2024
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.isci.2024.110199
  
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sciencedirect.com/science/article/pii/S258900422401424X
May 2024
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The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells

1
1. scibot 24 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.019
  
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sciencedirect.com/science/article/pii/S1534580724002946
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Substrate-bound and soluble domains of tenascin-C regulate differentiation, proliferation and migration of neural stem and progenitor cells

1
1. scibot 03 Mar 2024
  
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  DOI: 10.3389/fncel.2024.1357499
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10902920/
Feb 2024
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Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1

1
1. scibot 27 Feb 2024
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.celrep.2024.113837
  
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sciencedirect.com/science/article/pii/S2211124724001657
Jan 2024
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Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins

1
1. scibot 11 Jan 2024
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.celrep.2023.113627
  
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sciencedirect.com/science/article/pii/S2211124723016388
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The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling

1
1. scibot 06 Jan 2024
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.devcel.2023.12.002
  
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sciencedirect.com/science/article/pii/S1534580723006524
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VEGFR3 is required for button junction formation in lymphatic vessels

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1. scibot 20 Sep 2023
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.celrep.2023.112777
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10503778/
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Single-nuclei multiomic analyses identify human cardiac lymphatic endothelial cells associated with coronary arteries in the epicardium

1
1. scibot 08 Sep 2023
  
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  RRID:AB_2153348
  
  DOI: 10.1016/j.celrep.2023.113106
  
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sciencedirect.com/science/article/pii/S2211124723011178
Jul 2023
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Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112804
  
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sciencedirect.com/science/article/pii/S221112472300815X
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A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112819
  
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sciencedirect.com/science/article/pii/S2211124723008306
Apr 2023
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Unidirectional and phase-gated signaling synchronizes murine presomitic mesoderm cells

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.04.002
  
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  DOI: 10.1016/j.devcel.2023.04.002
  
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sciencedirect.com/science/article/pii/S1534580723001557
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Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.03.009
  
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sciencedirect.com/science/article/pii/S1534580723001053
Mar 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex

1
1. scibot 03 Mar 2023
  
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  DOI: 10.1111/jnc.15750
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15750
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity

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1. scibot 01 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.105962
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
Jan 2023
52.53.155.43 52.53.155.43

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

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1. scibot 14 Jan 2023
  
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  DOI: 10.1016/j.cell.2018.06.007
  
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52.53.155.43/c76b8bcf6e9bf144afd1467c4c10fd996e085648/SSRN-id4267408-html.html
Dec 2022
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Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma

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1. scibot 01 Dec 2022
  
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Prominin1 and Notch Regulate Ciliary Length and Dynamics in Multiciliated Cells of the Airway Epithelium.

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BPS Publications

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  DOI: 10.1111/bph.15904
  
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Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors

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SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal

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EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells

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Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity

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Dynamic stem cell selection safeguards the genomic integrity of the epidermis

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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition

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Nov 2021
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ajpheart.00125.2021-html.html

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Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway

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Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring

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Oct 2021
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MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer

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Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation

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Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding

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Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis

1
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Jul 2021
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Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis

1
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  DOI: 10.1016/j.nbd.2018.07.012
  
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May 2021
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Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

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Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis

1
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  DOI: 10.1016/j.cmet.2020.10.005
  
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In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

1
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Feb 2021
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Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis

1
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Nov 2020
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In utero exposure to maternal diabetes impairs nephron progenitor differentiation

1
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Oct 2020
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Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain

1
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Sep 2020
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Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

1
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Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

1
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Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

1
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  DOI: 10.7554/eLife.50684
  
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Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism

1
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  DOI: 10.7554/eLife.53659
  
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Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

1
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Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT

1
1. scibot 03 Sep 2020
  
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  anti-NICD1
  
  DOI: 10.1172/JCI128994
  
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Jan 2020
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PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism

1
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  DOI: 10.1016/j.stem.2019.08.017
  
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Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet

1
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  DOI: 10.1016/j.cell.2019.07.048
  
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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

1
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  DOI: 10.1016/j.ccell.2019.08.003
  
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Sox17 Regulates a Program of Oligodendrocyte Progenitor Cell Expansion and Differentiation during Development and Repair

1
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  DOI: 10.1016/j.celrep.2019.10.121
  
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Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation

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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.046
  
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Untitled document

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3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling

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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

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Paneth Cell Multipotency Induced by Notch Activation following Injury

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Dynamic Ligand Discrimination in the Notch Signaling Pathway

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Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells

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A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia

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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

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Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development

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