73 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    1. scibot 13 Dec 2024
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      DOI: 10.1038/s44321-024-00161-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
  3. www.sciencedirect.com www.sciencedirect.com
    Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery
    1
    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.stem.2024.10.015

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    sciencedirect.com/science/article/pii/S1934590924003771
  4. Nov 2024
  5. www.embopress.org www.embopress.org
    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
    1
    1. scibot 14 Nov 2024
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      DOI: 10.1038/s44318-024-00290-3

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    embopress.org/doi/10.1038/s44318-024-00290-3
  6. 52.53.155.43 52.53.155.43
    wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
    1
    1. scibot 14 Nov 2024
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    52.53.155.43/052dd78e8f9f0d46ee449e71fc9d1d608c537305/wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
    1
    1. scibot 07 Nov 2024
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      DOI: 10.3389/fimmu.2024.1470620

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    pmc.ncbi.nlm.nih.gov/articles/PMC11487346/
  8. Oct 2024
  9. www.embopress.org www.embopress.org
    SOX10 mediates glioblastoma cell-state plasticity
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1038/s44319-024-00258-8

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    embopress.org/doi/full/10.1038/s44319-024-00258-8
  10. Sep 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway
    1
    1. scibot 18 Sep 2024
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      DOI: 10.7554/eLife.90854

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    ncbi.nlm.nih.gov/pmc/articles/PMC11390110/
  12. Aug 2024
  13. www.cell.com www.cell.com
    Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility
    1
    1. scibot 18 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114582

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    cell.com/cell-reports/fulltext/S2211-1247(24)00911-2
  14. Jul 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Brain ischemia causes systemic Notch1 activity in endothelial cells to drive atherosclerosis
    1
    1. scibot 30 Jul 2024
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      DOI: 10.1016/j.immuni.2024.07.002

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    sciencedirect.com/science/article/pii/S1074761324003510
  16. Jun 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cmet.2024.05.013

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    sciencedirect.com/science/article/pii/S155041312400189X
  18. www.sciencedirect.com www.sciencedirect.com
    Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.isci.2024.110199

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    sciencedirect.com/science/article/pii/S258900422401424X
  19. May 2024
  20. www.sciencedirect.com www.sciencedirect.com
    The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.devcel.2024.04.019

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    sciencedirect.com/science/article/pii/S1534580724002946
  21. Mar 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substrate-bound and soluble domains of tenascin-C regulate differentiation, proliferation and migration of neural stem and progenitor cells
    1
    1. scibot 03 Mar 2024
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      DOI: 10.3389/fncel.2024.1357499

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    ncbi.nlm.nih.gov/pmc/articles/PMC10902920/
  23. Feb 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
    1
    1. scibot 27 Feb 2024
      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2024.113837

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    sciencedirect.com/science/article/pii/S2211124724001657
  25. Jan 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
    1
    1. scibot 11 Jan 2024
      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2023.113627

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    sciencedirect.com/science/article/pii/S2211124723016388
  27. www.sciencedirect.com www.sciencedirect.com
    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.002

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    sciencedirect.com/science/article/pii/S1534580723006524
  28. Sep 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VEGFR3 is required for button junction formation in lymphatic vessels
    1
    1. scibot 20 Sep 2023
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      DOI: 10.1016/j.celrep.2023.112777

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    ncbi.nlm.nih.gov/pmc/articles/PMC10503778/
  30. www.sciencedirect.com www.sciencedirect.com
    Single-nuclei multiomic analyses identify human cardiac lymphatic endothelial cells associated with coronary arteries in the epicardium
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113106

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    sciencedirect.com/science/article/pii/S2211124723011178
  31. Jul 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia
    1
    1. scibot 21 Jul 2023
      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2023.112804

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    sciencedirect.com/science/article/pii/S221112472300815X
  33. www.sciencedirect.com www.sciencedirect.com
    A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling
    1
    1. scibot 21 Jul 2023
      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2023.112819

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    sciencedirect.com/science/article/pii/S2211124723008306
  34. Apr 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Unidirectional and phase-gated signaling synchronizes murine presomitic mesoderm cells
    2
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.devcel.2023.04.002

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      DOI: 10.1016/j.devcel.2023.04.002

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    sciencedirect.com/science/article/pii/S1534580723001557
  36. www.sciencedirect.com www.sciencedirect.com
    Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.devcel.2023.03.009

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    sciencedirect.com/science/article/pii/S1534580723001053
  37. Mar 2023
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex
    1
    1. scibot 03 Mar 2023
      AB_2153348

      DOI: 10.1111/jnc.15750

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15750
  39. Feb 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
    1
    1. scibot 01 Feb 2023
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      DOI: 10.1016/j.isci.2023.105962

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
  41. Jan 2023
  42. 52.53.155.43 52.53.155.43
    Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels
    1
    1. scibot 14 Jan 2023
      RRID:AB_2153348

      DOI: 10.1016/j.cell.2018.06.007

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    52.53.155.43/c76b8bcf6e9bf144afd1467c4c10fd996e085648/SSRN-id4267408-html.html
  43. Dec 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111743

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    sciencedirect.com/science/article/pii/S2211124722016217
  45. Aug 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Prominin1 and Notch Regulate Ciliary Length and Dynamics in Multiciliated Cells of the Airway Epithelium.
    1
    1. scibot 02 Aug 2022
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      DOI: 10.1016/j.isci.2022.104751

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    sciencedirect.com/science/article/pii/S2589004222010239
  47. Jul 2022
  48. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 29 Jul 2022
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      DOI: 10.1111/bph.15904

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15904
  49. Apr 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock
    1
    1. scibot 14 Apr 2022
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      DOI: 10.1016/j.ydbio.2022.04.004

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    sciencedirect.com/science/article/pii/S0012160622000653
  51. Mar 2022
  52. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
    1
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      DOI: 10.1016/j.celrep.2022.110522

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    sciencedirect.com/science/article/pii/S2211124722002583
  53. www.sciencedirect.com www.sciencedirect.com
    SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal
    1
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      DOI: 10.1016/j.devcel.2022.01.011

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    sciencedirect.com/science/article/pii/S1534580722000363
  54. Feb 2022
  55. www.sciencedirect.com www.sciencedirect.com
    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
    1
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      DOI: 10.1016/j.molcel.2022.01.015

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    sciencedirect.com/science/article/pii/S1097276522000582
  56. www.sciencedirect.com www.sciencedirect.com
    Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
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      DOI: 10.1016/j.devcel.2022.01.006

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.devcel.2022.01.006

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    sciencedirect.com/science/article/pii/S1534580722000065
  57. Dec 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Dynamic stem cell selection safeguards the genomic integrity of the epidermis
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    sciencedirect.com/science/article/pii/S1534580721009424
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    The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
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      DOI: 10.1016/j.celrep.2021.110103

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    sciencedirect.com/science/article/pii/S2211124721015977
  60. Nov 2021
  61. 52.53.155.43 52.53.155.43
    ajpheart.00125.2021-html.html
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      DOI: 10.1152/ajpheart.00125.2021

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    52.53.155.43/97c82e9b6b3864243bc7b06ebc69cb131650363f/ajpheart.00125.2021-html.html
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway
    1
    1. scibot 05 Nov 2021
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      DOI: 10.21037/atm-21-1572

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    ncbi.nlm.nih.gov/pmc/articles/PMC8506556/
  63. www.sciencedirect.com www.sciencedirect.com
    Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
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      DOI: 10.1016/j.celrep.2021.109912

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  64. Oct 2021
  65. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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      DOI: 10.1016/j.isci.2021.103224

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  66. www.sciencedirect.com www.sciencedirect.com
    Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
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      RRID:AB_2153348

      DOI: 10.1016/j.devcel.2021.09.015

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  67. Aug 2021
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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      DOI: 10.1016/j.neuron.2021.07.007

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  69. www.sciencedirect.com www.sciencedirect.com
    Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis
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      RRID:AB_2153348

      DOI: 10.1016/j.nbd.2018.07.012

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  70. Jul 2021
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    Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis
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      DOI: 10.1016/j.nbd.2018.07.012

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  72. May 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population
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      DOI: 10.1016/j.devcel.2020.10.014

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  74. Apr 2021
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    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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      DOI: 10.1016/j.cmet.2020.10.005

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  76. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
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      DOI: 10.1016/j.cell.2021.02.021

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  77. Feb 2021
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    Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis
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      DOI: 10.1016/j.celrep.2020.108615

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  79. Nov 2020
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In utero exposure to maternal diabetes impairs nephron progenitor differentiation
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  81. Oct 2020
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    Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain
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      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2020.108268

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  83. Sep 2020
  84. www.sciencedirect.com www.sciencedirect.com
    Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia
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  85. www.sciencedirect.com www.sciencedirect.com
    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
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      DOI: 10.1016/j.devcel.2020.01.015

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells
    1
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      DOI: 10.7554/eLife.50684

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism
    1
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      DOI: 10.7554/eLife.53659

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  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
    1
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      RRID:AB_2153348

      DOI: 10.1016/j.devcel.2020.06.039

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  89. www.jci.org www.jci.org
    Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT
    1
    1. scibot 03 Sep 2020
      anti-NICD1

      DOI: 10.1172/JCI128994

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      Curator comments: Rabbit Anti-Notch1, cleaved (Val1744) XP??? Monoclonal Antibody, Unconjugated, Clone D3B8 Cell Signaling Technology Cat# 4147

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  90. Jan 2020
  91. www.sciencedirect.com www.sciencedirect.com
    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
    1
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      RRID:AB_2153348

      DOI: 10.1016/j.stem.2019.08.017

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    sciencedirect.com/science/article/pii/S1934590919303844
  92. www.sciencedirect.com www.sciencedirect.com
    Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
    1
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      RRID:AB_2153348

      DOI: 10.1016/j.cell.2019.07.048

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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
    1
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      RRID:AB_2153348

      DOI: 10.1016/j.ccell.2019.08.003

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  94. www.sciencedirect.com www.sciencedirect.com
    Sox17 Regulates a Program of Oligodendrocyte Progenitor Cell Expansion and Differentiation during Development and Repair
    1
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      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2019.10.121

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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation
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      RRID:AB_2153348

      DOI: 10.7554/eLife.50487

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  96. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2019.02.046

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    sciencedirect.com/science/article/pii/S2211124719302177
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      RRID:AB_2153348

      DOI: 10.1016/j.celrep.2019.01.023

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    sciencedirect.com/science/article/pii/S2211124719300324
  98. Nov 2018
  99. www.sciencedirect.com www.sciencedirect.com
    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    1
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    Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
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    Paneth Cell Multipotency Induced by Notch Activation following Injury
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    Dynamic Ligand Discrimination in the Notch Signaling Pathway
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    Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells
    1
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  104. europepmc.org europepmc.org
    A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia
    2
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  105. Nov 2017
  106. www.sciencedirect.com www.sciencedirect.com
    Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer
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      AB_2153348

      Curator: @chewbeccax

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  107. elifesciences.org elifesciences.org
    Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development
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      AB_2153348

      Curator: @gabimpine

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