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Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102478
  
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sciencedirect.com:5037/science/article/pii/S2666379125005518
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Exploring multiorgan mitochondrial dysfunction in the switch toward progressive MASLD in AMLN mice

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1. scibot 07 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113449
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12495477/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress

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1. scibot 06 Sep 2025
  
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  DOI: 10.1126/sciadv.ady0240
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12383277/
www.science.org www.science.org

Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress

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1. scibot 03 Sep 2025
  
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  DOI: 10.1126/sciadv.ady0240
  
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science.org/doi/10.1126/sciadv.ady0240
Jul 2025
www.nature.com www.nature.com

RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

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1. scibot 29 Jul 2025
  
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  DOI: 10.1038/s41388-025-03502-0
  
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nature.com/articles/s41388-025-03502-0
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PINK1 Loss of Function Selectively Alters the Mitochondrial‐Derived Vesicle Pathway

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1. scibot 15 Jul 2025
  
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  DOI: 10.1096/fba.2024-00200
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12242855/
Jun 2025
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Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102116
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147913/
May 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux

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1. scibot 20 May 2025
  
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  DOI: 10.1111/eci.70051
  
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onlinelibrary.wiley.com/doi/10.1111/eci.70051
Nov 2024
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Opposing roles for AMPK in regulating distinct mitophagy pathways

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1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.molcel.2024.10.025
  
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sciencedirect.com/science/article/pii/S1097276524008657
Mar 2024
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Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity

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1. scibot 02 Mar 2024
  
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  DOI: 10.1016/j.crmeth.2024.100712
  
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sciencedirect.com/science/article/pii/S2667237524000274
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Interaction of PINK1 with nucleotides and kinetin

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1. scibot 23 Jan 2024
  
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  DOI: 10.1126/sciadv.adj7408
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798554/
Jun 2023
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An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

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1. scibot 16 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.018
  
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sciencedirect.com/science/article/pii/S109727652300374X
Jan 2023
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Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

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1. scibot 11 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111941
  
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sciencedirect.com/science/article/pii/S2211124722018423
Jun 2022
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Prkn knockout mice show autistic-like behaviors and aberrant synapse formation

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1. scibot 30 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104573
  
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sciencedirect.com/science/article/pii/S2589004222008458
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Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease

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1. scibot 02 Jun 2022
  
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  DOI: 10.1016/j.neuron.2022.05.009
  
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sciencedirect.com/science/article/pii/S0896627322004500
May 2022
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Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults

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1. scibot 19 May 2022
  
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  DOI: 10.1016/j.xcrm.2022.100633
  
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sciencedirect.com/science/article/pii/S2666379122001586
Jan 2022
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Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase

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1. scibot 06 Jan 2022
  
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  DOI: 10.1016/j.isci.2021.103650
  
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sciencedirect.com/science/article/pii/S2589004221016205
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Roflupram attenuates α-synuclein-induced cytotoxicity and promotes the mitochondrial translocation of Parkin in SH-SY5Y cells overexpressing A53T mutant α-synuclein

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1. scibot 05 Jan 2022
  
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  DOI: 10.1016/j.taap.2021.115859
  
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sciencedirect.com/science/article/pii/S0041008X21004634
Aug 2021
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Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

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1. scibot 07 Aug 2021
  
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  DOI: 10.1016/j.cmet.2018.06.009
  
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sciencedirect.com/science/article/pii/S1550413118303917
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 01 Aug 2021
  
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  DOI: 10.1016/j.celrep.2018.07.101
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 29 Jul 2021
  
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  DOI: 10.1016/j.neuron.2017.01.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5340420/
rupress.org rupress.org

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination

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1. scibot 23 Jul 2021
  
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  DOI: 10.1083/jcb.202006043
  
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rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
Feb 2021
bmcpulmmed.biomedcentral.com bmcpulmmed.biomedcentral.com

Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle

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1. scibot 24 Feb 2021
  
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  DOI: 10.1186/s12890-020-1047-8
  
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2. scibot 24 Feb 2021
  
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  DOI: 10.1186/s12890-020-1047-8
  
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bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-020-1047-8
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

FOXO3a‐dependent Parkin regulates the development of gastric cancer by targeting ATP‐binding cassette transporter E1

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1. scibot 17 Sep 2020
  
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  DOI: 10.1002/jcp.30040
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.30040
Jan 2020
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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2018.11.034
  
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sciencedirect.com/science/article/pii/S1097276518310049
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124718312348
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UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518304441
Nov 2017
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Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S009286741631652X
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Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S0896627317300430