Hypothesis

52 Matching Annotations

Nov 2025
54.241.53.176 54.241.53.176

2025.11.16.688689v1.full-html.html

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1. scibot 22 Nov 2025
  
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  DOI: 10.1101/2025.11.16.688689
  
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54.241.53.176/ff0938d0c3d1496c2bb0e0f01693e3b2e489e60f/2025.11.16.688689v1.full-html.html
Jun 2025
www.sciencedirect.com www.sciencedirect.com

PTEN protein phosphatase activity regulates metastasis by targeting PKCδ

1
1. scibot 12 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112741
  
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sciencedirect.com/science/article/pii/S2589004225010028
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225009344-main-html.html

1
1. scibot 18 May 2025
  
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  AB_2173659
  
  DOI: 10.1016/j.isci.2025.112673
  
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52.53.155.43/e92b07ea6d3b21022cca859701890e2812640a41/1-s2.0-S2589004225009344-main-html.html
Feb 2025
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N-cadherin-triggered myosin II inactivation provides tumor cells with a mechanical cell competition advantage and chemotherapy resistance

1
1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.020
  
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sciencedirect.com/science/article/pii/S1534580725000619
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases

1
1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101943
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866499/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Coordination of Focal Adhesion Nanoarchitecture and Dynamics in Mechanosensing for Cardiomyoblast Differentiation

1
1. scibot 27 Jan 2025
  
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  DOI: 10.1021/acsami.4c15459
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11758775/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225001166-main-html.html

1
1. scibot 23 Jan 2025
  
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  AB_2173659
  
  DOI: 10.1016/j.isci.2025.111856
  
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52.53.155.43/f7a3e96df7edf052e7c2acc984abc4e530aec8c5/1-s2.0-S2589004225001166-main-html.html
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1038/s41417-024-00809-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405271/
Jun 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo

1
1. scibot 06 Jun 2024
  
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  DOI: 10.1002/dneu.22950
  
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onlinelibrary.wiley.com/doi/10.1002/dneu.22950
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

1
1. scibot 27 Apr 2024
  
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  DOI: 10.7554/eLife.94265
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
Mar 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Astrocyte focal adhesion kinase reduces passive stress coping by inhibiting ciliary neurotrophic factor only in female mice

1
1. scibot 13 Mar 2024
  
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  DOI: 10.1016/j.ynstr.2024.100621
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10955429/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Substrate-bound and soluble domains of tenascin-C regulate differentiation, proliferation and migration of neural stem and progenitor cells

1
1. scibot 03 Mar 2024
  
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  RRID:AB_2173659
  
  DOI: 10.3389/fncel.2024.1357499
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10902920/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner

1
1. scibot 10 Jan 2024
  
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  RRID:AB_2173659
  
  DOI: 10.1158/1078-0432.CCR-23-0964
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10767302/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function

1
1. scibot 02 Nov 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.celrep.2023.113326
  
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sciencedirect.com/science/article/pii/S2211124723013384
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling

1
1. scibot 06 Oct 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.neuron.2023.08.012
  
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sciencedirect.com/science/article/pii/S0896627323006232
Sep 2023
academic.oup.com academic.oup.com

bvad117-html.html

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1. scibot 20 Sep 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1210/jendso/bvad117
  
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2. scibot 20 Sep 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1210/jendso/bvad117
  
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academic.oup.com/jes/article/7/10/bvad117/7274808
Jul 2023
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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling

1
1. scibot 14 Jul 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.ccell.2023.06.007
  
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sciencedirect.com/science/article/pii/S1535610823002179
Jun 2023
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Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α

1
1. scibot 02 Jun 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.molcel.2023.05.008
  
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sciencedirect.com/science/article/pii/S1097276523003325
May 2023
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Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity

1
1. scibot 26 May 2023
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.ccell.2023.04.018
  
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sciencedirect.com/science/article/pii/S1535610823001629
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion

1
1. scibot 08 Apr 2023
  
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  RRID:AB_2173659
  
  DOI: 10.7554/eLife.86971
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
Mar 2023
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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis

1
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  RRID:AB_2173659
  
  DOI: 10.1016/j.celrep.2023.112164
  
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sciencedirect.com/science/article/pii/S2211124723001754
Nov 2022
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RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

1
1. scibot 10 Nov 2022
  
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  DOI: 10.1016/j.isci.2022.105184
  
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sciencedirect.com/science/article/pii/S2589004222014560
Aug 2022
journals.plos.org journals.plos.org

Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions

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1. scibot 31 Aug 2022
  
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  RRID:AB_2173659
  
  DOI: 10.1371/journal.pbio.3001759
  
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journals.plos.org/plosbiology/article
Jul 2022
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Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover

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1. scibot 12 Jul 2022
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.devcel.2022.06.011
  
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sciencedirect.com/science/article/pii/S1534580722004518
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth

1
1. scibot 09 Jul 2022
  
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  RRID:AB_2173659
  
  DOI: 10.7554/eLife.78972
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9259034/
Jun 2022
journals.sagepub.com journals.sagepub.com

Female-specific neuroprotection after ischemic stroke by vitronectin-focal adhesion kinase inhibition - Cuihong Jia, Chiharu Lovins, Hannah M Malone, Matthew P Keasey, Theo Hagg, 2022

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1. scibot 22 Jun 2022
  
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  RRID:AB_2173659
  
  DOI: 10.1177/0271678X221107871
  
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journals.sagepub.com/doi/full/10.1177/0271678X221107871
May 2022
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice

1
1. scibot 10 May 2022
  
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  RRID:AB_2173659
  
  DOI: 10.14814/phy2.15301
  
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physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15301
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Translational Strategies for Repotrectinib in Neuroblastoma

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1. scibot 05 May 2022
  
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  DOI: 10.1158/1535-7163.MCT-21-0126
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8571000/
Apr 2022
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Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice

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1. scibot 21 Apr 2022
  
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  Cell Signaling TechnologyCat# 3283
  
  DOI: 10.1016/j.xcrm.2022.100597
  
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sciencedirect.com/science/article/pii/S2666379122001148
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Mucin 5AC–Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity

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1. scibot 08 Apr 2022
  
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  DOI: 10.1053/j.gastro.2022.02.032
  
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sciencedirect.com/science/article/pii/S0016508522001986
Mar 2022
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Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus

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1. scibot 02 Mar 2022
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.ebiom.2022.103903
  
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sciencedirect.com/science/article/pii/S2352396422000871
Dec 2021
link.springer.com link.springer.com

PDIA3 inhibits mitochondrial respiratory function in brain endothelial cells and C. elegans through STAT3 signaling and decreases survival after OGD

1
1. scibot 21 Dec 2021
  
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  DOI: 10.1186/s12964-021-00794-z
  
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link.springer.com/article/10.1186/s12964-021-00794-z
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1

1
1. scibot 28 Oct 2021
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.isci.2021.103189
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8521174/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deiodinase-3 is a thyrostat to regulate podocyte homeostasis

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1. scibot 23 Oct 2021
  
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  RRID:AB_2173659
  
  DOI: 10.1016/j.ebiom.2021.103617
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8517284/
Jul 2021
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Inhibition of astrocyte FAK–JNK signaling promotes subventricular zone neurogenesis through CNTF

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Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

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Deciphering the signaling network of breast cancer improves drug sensitivity prediction

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CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

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Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

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Embryonic Stem-Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK

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Sep 2020
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Inhibition of astrocyte FAK–JNK signaling promotes subventricular zone neurogenesis through CNTF

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Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness

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Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation

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Activation of FAK/Rac1/Cdc42‐GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss‐of‐function murine models

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Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin–FAK and uPAR signaling

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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

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A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐ angiogenesis effects via targeting VEGFR‐2 signaling

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Vitronectin mitigates stroke-increased neurogenesis only in female mice and through FAK-regulated IL-6

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Untitled document

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Nov 2018
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Systematic Functional Annotation of Somatic Mutations in Cancer

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Nov 2017
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Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks

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