46 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A negatively-charged region within carboxy-terminal domain maintains proper CTCF DNA binding
    1
    1. scibot 14 Dec 2024
      RRID:AB_2176601

      DOI: 10.1016/j.isci.2024.111452

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    sciencedirect.com/science/article/pii/S2589004224026798
  3. Jul 2024
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    STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia
    1
    1. scibot 31 Jul 2024
      RRID:AB_2176601

      DOI: 10.1016/j.celrep.2024.114498

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    sciencedirect.com/science/article/pii/S2211124724008271
  5. May 2024
  6. www.sciencedirect.com www.sciencedirect.com
    A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification
    1
    1. scibot 02 May 2024
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      DOI: 10.1016/j.immuni.2024.04.007

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    sciencedirect.com/science/article/pii/S1074761324002127
  7. Apr 2024
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    SAFB restricts contact domain boundaries associated with L1 chimeric transcription
    1
    1. scibot 11 Apr 2024
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2024.03.021

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    sciencedirect.com/science/article/pii/S1097276524002314
  9. Jan 2024
  10. www.sciencedirect.com www.sciencedirect.com
    PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.015

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    sciencedirect.com/science/article/pii/S1534580723006962
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    ZNF143 deletion alters enhancer/promoter looping and CTCF/cohesin geometry
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113663

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    sciencedirect.com/science/article/pii/S2211124723016741
  12. Dec 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Super-enhancers include classical enhancers and facilitators to fully activate gene expression
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.cell.2023.11.030

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    sciencedirect.com/science/article/pii/S0092867423013168
  14. Mar 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus
    1
    1. scibot 30 Mar 2023
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      DOI: 10.1016/j.molcel.2023.03.009

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    sciencedirect.com/science/article/pii/S1097276523001661
  16. Feb 2023
  17. www.science.org www.science.org
    Multiscale 3D genome reorganization during skeletal muscle stem cell lineage progression and aging
    1
    1. scibot 23 Feb 2023
      RRID:AB_2176601

      DOI: 10.1126/sciadv.abo1360

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    science.org/doi/10.1126/sciadv.abo1360
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiscale 3D genome reorganization during skeletal muscle stem cell lineage progression and aging
    1
    1. scibot 23 Feb 2023
      RRID:AB_2176601

      DOI: 10.1126/sciadv.abo1360

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    ncbi.nlm.nih.gov/pmc/articles/PMC9937580/
  19. www.sciencedirect.com www.sciencedirect.com
    A de novo transcription-dependent TAD boundary underpins critical multiway interactions during antibody class switch recombination
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.molcel.2023.01.014

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    sciencedirect.com/science/article/pii/S1097276523000370
  20. Dec 2022
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
    1
    1. scibot 30 Dec 2022
      RRID:AB_2176601

      DOI: 10.1016/j.isci.2022.105695

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    ncbi.nlm.nih.gov/pmc/articles/PMC9792897/
  22. Nov 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Essential role of MESP1-RING1A complex in cardiac differentiation
    1
    1. scibot 22 Nov 2022
      RRID:AB_2176601

      DOI: 10.1016/j.devcel.2022.10.009

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    sciencedirect.com/science/article/pii/S1534580722007614
  24. Oct 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Chromatin jets define the properties of cohesin-driven in vivo loop extrusion
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.molcel.2022.09.003

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    sciencedirect.com/science/article/pii/S1097276522008541
  26. May 2022
  27. www.nature.com www.nature.com
    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
    1
    1. scibot 26 May 2022
      RRID:AB_2176601

      DOI: 10.1038/s41598-022-12188-3

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    nature.com/articles/s41598-022-12188-3
  28. Apr 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
    1
    1. scibot 07 Apr 2022
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2022.03.018

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    sciencedirect.com/science/article/pii/S1097276522002568
  30. Feb 2022
  31. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    1. scibot 18 Feb 2022
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  32. Dec 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops
    1
    1. scibot 02 Dec 2021
      RRID:AB_2176601

      DOI: 10.1016/j.cell.2021.11.012

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    sciencedirect.com/science/article/pii/S0092867421013271
  34. Aug 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 03 Aug 2021
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2018.11.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC6344341/
  36. www.nature.com www.nature.com
    Untitled document
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    1. scibot 01 Aug 2021
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      DOI: 10.1038/s41586-018-0845-0

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    nature.com/articles/s41586-018-0845-0 
  37. Jul 2021
  38. www.sciencedirect.com www.sciencedirect.com
    Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency
    1
    1. scibot 27 Jul 2021
      AB_2176601

      DOI: 10.1016/j.cels.2018.09.003

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    sciencedirect.com/science/article/pii/S2405471218303892
  39. www.sciencedirect.com www.sciencedirect.com
    Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress
    1
    1. scibot 27 Jul 2021
      RRID:AB_21176601

      DOI: 10.1016/j.molcel.2018.07.012

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    sciencedirect.com/science/article/pii/S1097276518305811
  40. www.cell.com www.cell.com
    Transcription-mediated supercoiling regulates genome folding and loop formation
    1
    1. scibot 23 Jul 2021
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2021.06.009

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00456-1
  41. www.sciencedirect.com www.sciencedirect.com
    Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression
    1
    1. scibot 01 Jul 2021
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      DOI: 10.1016/j.molcel.2021.06.008

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    sciencedirect.com/science/article/pii/S109727652100455X
  42. Jun 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation
    1
    1. scibot 26 Jun 2021
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      DOI: 10.1016/j.isci.2021.102660

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    ncbi.nlm.nih.gov/pmc/articles/PMC8209278/
  44. May 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Balancing cohesin eviction and retention prevents aberrant chromosomal interactions, Polycomb-mediated repression, and X-inactivation
    1
    1. scibot 08 May 2021
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2021.02.031

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    sciencedirect.com/science/article/pii/S1097276521001416
  46. Apr 2021
  47. www.sciencedirect.com www.sciencedirect.com
    STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
    1
    1. scibot 30 Apr 2021
      RRID:AB_2176601

      DOI: 10.1016/j.ccell.2021.04.001

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    sciencedirect.com/science/article/pii/S1535610821002087
  48. Feb 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
    1
    1. scibot 25 Feb 2021
      RRID:AB_2176601

      DOI: 10.1016/j.celrep.2021.108783

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    sciencedirect.com/science/article/pii/S2211124721000966
  50. Nov 2020
  51. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
    1
    1. scibot 03 Nov 2020
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      DOI: 10.1016/j.molcel.2020.10.005

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    pubmed.ncbi.nlm.nih.gov/33108759/
  52. Sep 2020
  53. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder
    1
    1. scibot 29 Sep 2020
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      DOI: 10.1016/j.stem.2020.09.001

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    pubmed.ncbi.nlm.nih.gov/32991838/
  54. www.sciencedirect.com www.sciencedirect.com
    Cohesin Removal Reprograms Gene Expression upon Mitotic Entry
    1
    1. scibot 17 Sep 2020
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      DOI: 10.1016/j.molcel.2020.01.023

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    sciencedirect.com/science/article/pii/S1097276520300447
  55. www.sciencedirect.com www.sciencedirect.com
    Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor
    1
    1. scibot 10 Sep 2020
      RRID:AB_2176601

      DOI: 10.1016/j.celrep.2020.107803

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    sciencedirect.com/science/article/pii/S2211124720307841
  56. www.cell.com www.cell.com
    Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability
    1
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      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2018.11.001

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    cell.com/molecular-cell/abstract/S1097-2765(18)30943-2
  57. Jan 2020
  58. www.sciencedirect.com www.sciencedirect.com
    A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers
    1
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      RRID:AB_2176601

      DOI: 10.1016/j.cell.2019.07.011

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    sciencedirect.com/science/article/pii/S0092867419307767
  59. www.sciencedirect.com www.sciencedirect.com
    The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cell.2019.08.007

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    sciencedirect.com/science/article/pii/S0092867419308955
  60. www.sciencedirect.com www.sciencedirect.com
    Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity
    1
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      DOI: 10.1016/j.molcel.2019.04.030

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    sciencedirect.com/science/article/pii/S1097276519303223
  61. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2176601

      DOI: 10.1016/j.cub.2019.02.007

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    sciencedirect.com/science/article/pii/S0960982219301460
  62. www.nature.com www.nature.com
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      DOI: 10.1038/s41586-018-0845-0

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    nature.com/articles/s41586-018-0845-0
  63. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2176601

      DOI: 10.1016/j.molcel.2018.11.001

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    sciencedirect.com/science/article/pii/S1097276518309432
  64. Nov 2018
  65. www.sciencedirect.com www.sciencedirect.com
    The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1074761318303960
  66. www.sciencedirect.com www.sciencedirect.com
    Polymer Simulations of Heteromorphic Chromatin Predict the 3D Folding of Complex Genomic Loci
    1
    1. scibot 05 Nov 2018
      RRID:AB_2176601

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518307871
  67. elifesciences.org elifesciences.org
    Computational prediction of CTCF/cohesin-based intra-TAD loops that insulate chromatin contacts and gene expression in mouse liver
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    1. scibot 05 Nov 2018
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      Curator: @evieth

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    elifesciences.org/articles/34077
  68. www.sciencedirect.com www.sciencedirect.com
    HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types
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    1. scibot 05 Nov 2018
      RRID:AB_2176601

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      (Abcam Cat# ab992, RRID:AB_2176601)

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    sciencedirect.com/science/article/pii/S1097276518302338
  69. www.sciencedirect.com www.sciencedirect.com
    Cohesin Loss Eliminates All Loop Domains
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    1. scibot 05 Nov 2018
      RRID:AB_2176601

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    sciencedirect.com/science/article/pii/S0092867417311200
  70. Nov 2017
  71. www.sciencedirect.com www.sciencedirect.com
    Genome Organization Drives Chromosome Fragility
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    1. scibot 08 Nov 2017
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867417307183
  72. www.sciencedirect.com www.sciencedirect.com
    Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region
    1
    1. scibot 08 Nov 2017
      RRID: AB_2176601

      Curator: @chewbeccax

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      (Abcam Cat# ab992, RRID:AB_2176601)

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    sciencedirect.com/science/article/pii/S1074761316303363