Hypothesis

20 Matching Annotations

Apr 2024
52.53.155.43 52.53.155.43

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

1
1. scibot 11 Apr 2024
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.isci.2024.109576
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

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52.53.155.43/43deb73e3f715bad3d2167b3c6b37658d9cd796b/1-s2.0-S2589004224007983-main-html.html
www.sciencedirect.com www.sciencedirect.com

A senescence restriction point acting on chromatin integrates oncogenic signals

1
1. scibot 04 Apr 2024
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2024.114044
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

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sciencedirect.com/science/article/pii/S2211124724003723
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.ccell.2023.11.001
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

URL

sciencedirect.com/science/article/pii/S1535610823003665
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

1
1. scibot 12 Apr 2023
  
  in Public
  
  AB_2184205
  
  DOI: 10.1158/0008-5472.CAN-22-2129
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10071820/
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Gramine protects against pressure overload-induced pathological cardiac hypertrophy through Runx1-TGFBR1 signaling

1
1. scibot 28 Mar 2023
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.phymed.2023.154779
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

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sciencedirect.com/science/article/pii/S094471132300140X
Sep 2022
www.nature.com www.nature.com

A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice

1
1. scibot 10 Sep 2022
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1038/s42003-022-03917-5
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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URL

nature.com/articles/s42003-022-03917-5
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia

1
1. scibot 22 Sep 2021
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2021.109725
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

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sciencedirect.com/science/article/pii/S2211124721011748
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2018.12.098
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205 RRIDCUR:Unrecognized
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RRID:AB_2184205

RRIDCUR:Unrecognized

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scibot

URL

sciencedirect.com/science/article/pii/S2211124718320588
May 2021
www.sciencedirect.com www.sciencedirect.com

RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2021.109102
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721004368
www.sciencedirect.com www.sciencedirect.com

Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells

1
1. scibot 04 May 2021
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.stem.2021.04.008
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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URL

sciencedirect.com/science/article/pii/S193459092100165X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

1
1. scibot 21 Apr 2021
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2021.109010
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Validated
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721003247
Feb 2021
www.sciencedirect.com www.sciencedirect.com

The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.molcel.2020.12.040
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2184205
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1097276520309618
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells

1
1. scibot 17 Sep 2020
  
  in Public
  
  AB_2184205
  
  DOI: 10.1016/j.celrep.2020.107688
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2184205
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720306410
www.sciencedirect.com www.sciencedirect.com

CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia

1
1. scibot 08 Sep 2020
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2019.12.026
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Validated
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719316766
www.sciencedirect.com www.sciencedirect.com

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2020.107691
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Validated
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720306446
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID: AB_2184205
  
  DOI: 10.1158/2159-8290.CD-19-0471
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2184205
  
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  RRID:AB_2184205
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RRID:AB_2184205

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scibot

URL

cancerdiscovery.aacrjournals.org/content/9/12/1774
Jan 2020
www.sciencedirect.com www.sciencedirect.com

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2019.08.040
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Validated
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719310800
www.sciencedirect.com www.sciencedirect.com

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.ccell.2019.10.011
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Validated
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819304854
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2184205
  
  DOI: 10.1016/j.celrep.2018.11.039
  
  Resource: (Abcam Cat# ab23980, RRID:AB_2184205)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2184205
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Validated
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RRID:AB_2184205

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124718318023
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1

1
1. scibot 05 Nov 2018
  
  in Public
  
  RUNX1 (Western) (1ug/ml)Abcam#ab23980
  
  Curator: @evieth
  
  Resource used:
  
  (Abcam Cat# ab23980, RRID:AB_2184205)
  
  SciCrunch record: RRID:AB_2184205
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2184205 RRIDCUR:Missing
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RRID:AB_2184205

RRIDCUR:Missing

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5807056/