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CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer

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1. scibot 01 Aug 2026
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.cell.2026.07.016
  
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sciencedirect.com/science/article/pii/S0092867426008147
Jul 2026
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LEF1 and niche factors determine T cell stemness across chronic diseases

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1. scibot 04 Jul 2026
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.cell.2026.06.022
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S0092867426007099
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

The transcription factor Helios restrains the anti-tumor capacity of CD8+ T cells

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1. scibot 13 Dec 2025
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.celrep.2025.116680
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
  Curator: @scibot
  
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sciencedirect.com:5037/science/article/pii/S2211124725014524
Dec 2024
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Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells

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1. scibot 02 Dec 2024
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.celrep.2024.115023
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S2211124724013743
Jul 2024
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Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation

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1. scibot 25 Jul 2024
  
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  AB_2188095
  
  DOI: 10.1016/j.immuni.2024.06.014
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S1074761324003200
Jun 2024
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A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice

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1. scibot 06 Jun 2024
  
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  RRID:AB_2188095
  
  DOI: 10.1038/s41590-024-01834-9
  
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nature.com/articles/s41590-024-01834-9
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Progenitors of distinct lineages shape the diversity of mature type 2 conventional dendritic cells

1
1. scibot 04 Jun 2024
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.immuni.2024.05.007
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S1074761324002607
May 2024
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

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1. scibot 21 May 2024
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.cell.2024.04.025
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S0092867424004513
Feb 2024
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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48

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1. scibot 22 Feb 2024
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.celrep.2024.113800
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S2211124724001281
Dec 2023
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

1
1. scibot 17 Dec 2023
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.immuni.2023.11.005
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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sciencedirect.com/science/article/pii/S1074761323004879
Oct 2023
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Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma

1
1. scibot 13 Oct 2023
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.ccell.2023.09.011
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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  SciCrunch record: RRID:AB_2188095
  
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sciencedirect.com/science/article/pii/S1535610823003276
Apr 2022
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Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches

1
1. scibot 07 Apr 2022
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.immuni.2022.03.006
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761322001297
Sep 2021
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A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma

1
1. scibot 17 Sep 2021
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.crmeth.2021.100080
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
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  SciCrunch record: RRID:AB_2188095
  
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sciencedirect.com/science/article/pii/S2667237521001351
Apr 2021
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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

1
1. scibot 15 Apr 2021
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.celrep.2021.108966
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2188095
  
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  RRID:AB_2188095 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721002801
Sep 2020
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

1
1. scibot 07 Sep 2020
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.immuni.2020.04.014
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2188095
  
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  RRIDCUR:Validated RRID:AB_2188095
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pmc.ncbi.nlm.nih.gov/articles/PMC8360766/
Jan 2020
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2188095
  
  DOI: 10.1016/j.immuni.2018.12.021
  
  Resource: (BioLegend Cat# 134606, RRID:AB_2188095)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2188095
  
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  RRID:AB_2188095 RRIDCUR:Validated
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RRID:AB_2188095

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sciencedirect.com/science/article/pii/S1074761318305697