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EZH1/2 inhibition improves immunotherapy response through MHC Class II de-repression and neutrophil reprogramming

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1. scibot 11 Jun 2026
  
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  DOI: 10.64898/2026.06.01.725956
  
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biorxiv.org/content/10.64898/2026.06.01.725956v1
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The circadian clock component BMAL1 enhances macrophage inflammation by nuclear translocation of peroxisomal β-oxidation enzyme MFP2

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1. scibot 11 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117480
  
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sciencedirect.com/science/article/pii/S2211124726005589
Jan 2026
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Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.043
  
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cell.com/cell/fulltext/S0092-8674(25)01492-8
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e013832.full-html.html

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1. scibot 27 Jan 2026
  
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  AB_2191071
  
  DOI: 10.1136/jitc-2025-013832
  
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54.241.53.176/ca60c4c2a1e906c1762fed2c822dc77ccf0438f0/e013832.full-html.html
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti–PD-1 Immunotherapy

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1. scibot 03 Dec 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3095
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12666320/
Oct 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Epithelial Memory After Respiratory Viral Infection in Mice Results in Prolonged Enhancement of Antigen Presentation

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1. scibot 04 Oct 2025
  
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  DOI: 10.1111/all.16683
  
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onlinelibrary.wiley.com/doi/10.1111/all.16683
Aug 2025
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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.chom.2025.08.001
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12471108/
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Bifidobacterium animalis suppresses non-small cell lung cancer progression and modulates tumor immunity through indole-3-acetic acid

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116132
  
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sciencedirect.com/science/article/pii/S2211124725009039
Jul 2025
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BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma

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1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102258
  
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sciencedirect.com/science/article/pii/S2666379125003313
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Interferon-driven CAF reprogramming augments immunogenic response to neoadjuvant radiotherapy in colorectal cancer

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102251
  
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sciencedirect.com/science/article/pii/S2666379125003246
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Cognate interaction-dependent pathogenicity of meningeal B cells drives neuroinflammation relapse

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.016
  
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sciencedirect.com/science/article/pii/S1074761325002857
Jun 2025
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Probiotic-mediated tumor microenvironment reprogramming with protease-sensitive interleukin-15 and photothermal therapy

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1. scibot 18 Jun 2025
  
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  RRID:AB_2191071
  
  DOI: 10.1016/j.xcrm.2025.102191
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12208336/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225010351-main (1)-html.html

1
1. scibot 13 Jun 2025
  
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  RRID:AB_2191071
  
  DOI: 10.1016/j.isci.2025.112774
  
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52.53.155.43/4b335a8bbb2cbd12d3073f7f7af0232585278bec/1-s2.0-S2589004225010351-main (1)-html.html
May 2025
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MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer

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1. scibot 20 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115722
  
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sciencedirect.com/science/article/pii/S2211124725004930
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Trajectories of macrophage ontogeny and reprogramming in cancer

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112498
  
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sciencedirect.com/science/article/pii/S258900422500759X
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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.006
  
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sciencedirect.com/science/article/pii/S1074761325001694
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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice

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1. scibot 17 May 2025
  
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  RRID:AB_2191071
  
  DOI: 10.1016/j.ebiom.2025.105734
  
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sciencedirect.com/science/article/pii/S2352396425001781
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases

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1. scibot 23 Jan 2025
  
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  DOI: 10.7554/eLife.99010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750138/
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Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115125
  
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sciencedirect.com/science/article/pii/S2211124724014761
Dec 2024
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.008
  
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sciencedirect.com/science/article/pii/S1535610824004434
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Gingival spatial analysis reveals geographic immunological variation in a microbiota-dependent and -independent manner

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1. scibot 06 Dec 2024
  
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  DOI: 10.1038/s41522-024-00625-2
  
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nature.com/articles/s41522-024-00625-2
Sep 2024
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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101718
  
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sciencedirect.com/science/article/pii/S2666379124004397
Jul 2024
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Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.014
  
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sciencedirect.com/science/article/pii/S1535610824002393
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Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity

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1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293343/
May 2024
52.53.155.43 52.53.155.43

Gingival-derived mesenchymal stem cells alleviate allergic asthma inflammation via HGF in animal models

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1. scibot 10 May 2024
  
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  DOI: 10.1016/j.isci.2024.109818
  
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52.53.155.43/77b0b81fcd376689bbdc4cf0ee4300be323e1a77/PIIS258900422401040X-html.html
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas

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1. scibot 15 Feb 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0399
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
Sep 2023
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In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities

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1. scibot 07 Sep 2023
  
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  DOI: 10.1158/2643-3230.BCD-22-0082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9975769/
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Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity

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1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107719
  
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Aug 2023
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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

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1. scibot 26 Aug 2023
  
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  DOI: 10.1016/j.xcrm.2023.101130
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10439247/
Feb 2023
52.53.155.43 52.53.155.43

bcd-22-0082-html.html

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1. scibot 11 Feb 2023
  
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  DOI: 10.1158/2643-3230.bcd-22-0082
  
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52.53.155.43/479e0586fccc84d0ed0a91d33d7fb0443934a0b7/bcd-22-0082-html.html
Nov 2022
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DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

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1. scibot 23 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111703
  
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sciencedirect.com/science/article/pii/S2211124722015777
Oct 2022
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Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

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1. scibot 13 Oct 2022
  
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  DOI: 10.1016/j.immuni.2022.09.005
  
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sciencedirect.com/science/article/pii/S107476132200499X
May 2022
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Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut

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1. scibot 11 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110773
  
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sciencedirect.com/science/article/pii/S221112472200537X
Apr 2022
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An in vivo orthotopic serial passaging model for a metastatic renal cancer study

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1. scibot 21 Apr 2022
  
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  RRID:AB_2191071
  
  DOI: 10.1016/j.xpro.2022.101306
  
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sciencedirect.com/science/article/pii/S2666166722001861
Sep 2021
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Isolation of mouse Kupffer cells for phenotypic and functional studies

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  DOI: 10.1016/j.xpro.2021.100831
  
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Jun 2021
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Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

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  DOI: 10.1371/journal.ppat.1009593
  
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A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis

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  DOI: 10.7554/eLife.66222
  
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May 2021
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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.immuni.2020.10.001
  
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Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cels.2019.01.004
  
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  DOI: 10.1016/j.immuni.2019.04.010
  
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