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    RNA sensing induced by chromosome missegregation augments anti-tumor immunity
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  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11634986/
  5. Nov 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
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    1. scibot 07 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  7. Sep 2024
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    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
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    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
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    sciencedirect.com/science/article/pii/S2589004224021187
  10. Aug 2024
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    sciencedirect.com/science/article/pii/S1097276524006609
  12. Jun 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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      DOI: 10.1038/s44320-024-00040-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148061/
  14. May 2024
  15. aacrjournals.org aacrjournals.org
    TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity
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    aacrjournals.org/cancerdiscovery/article/14/5/752/745044/TREX1-Inactivation-Unleashes-Cancer-Cell-STING
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    Development of nitroalkene-based inhibitors to target STING-dependent inflammation
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    sciencedirect.com/science/article/pii/S2213231724001800
  17. Apr 2024
  18. www.sciencedirect.com www.sciencedirect.com
    ISGylation by HERCs facilitates STING activation
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  19. Nov 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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    1. scibot 30 Nov 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  21. Sep 2023
  22. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    1. scibot 30 Sep 2023
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    biorxiv.org/content/10.1101/2023.09.25.559255v1
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    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
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    sciencedirect.com/science/article/pii/S2211124723011191
  24. Mar 2023
  25. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
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    europepmc.org/article/med/36952341
  26. europepmc.org europepmc.org
    UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS
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    europepmc.org/article/med/36943869
  27. Feb 2023
  28. www.cell.com www.cell.com
    Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma
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    cell.com/cell-reports/fulltext/S2211-1247(23)00138-9
  29. Jan 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response
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    sciencedirect.com/science/article/pii/S1097276522011649
  31. Sep 2022
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    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610822003798
  33. Jul 2022
  34. aacrjournals.org aacrjournals.org
    Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer
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    1. scibot 31 Jul 2022
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    aacrjournals.org/cancerrescommun/article/2/7/706/707154/Potent-Stimulation-of-the-Androgen-Receptor
  35. Jan 2022
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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    sciencedirect.com/science/article/pii/S1535610821006620
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    SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model
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      DOI: 10.1016/j.ebiom.2021.103808

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    sciencedirect.com/science/article/pii/S2352396421006022
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    Native-PAGE analysis of protein aggregation upon viral infection in mouse macrophages
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    1. scibot 11 Jan 2022
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    sciencedirect.com/science/article/pii/S2666166721007863
  39. Oct 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
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      DOI: 10.7554/eLife.72328

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    ncbi.nlm.nih.gov/pmc/articles/PMC8523161/
  41. Sep 2021
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    The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation
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    sciencedirect.com/science/article/pii/S2211124721011803
  43. Aug 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
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      DOI: 10.1016/j.cell.2021.07.026

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    sciencedirect.com/science/article/pii/S0092867421008850
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    Untitled document
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      DOI: 10.1016/j.celrep.2018.10.057

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    sciencedirect.com/science/article/pii/S2211124718316462
  46. Apr 2021
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    TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
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      DOI: 10.1016/j.cmet.2020.10.010

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    sciencedirect.com/science/article/pii/S155041312030543X
  48. Jan 2021
  49. www.sciencedirect.com www.sciencedirect.com
    A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
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    sciencedirect.com/science/article/pii/S2211124720315758
  50. Dec 2020
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
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      DOI: 10.1016/j.celrep.2019.03.098

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    ncbi.nlm.nih.gov/pmc/articles/PMC7733315/
  52. Sep 2020
  53. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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      DOI: 10.1016/j.celrep.2020.03.056

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    sciencedirect.com/science/article/pii/S2211124720303703
  54. rupress.org rupress.org
    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
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      DOI: 10.1083/jcb.201912144

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    rupress.org/jcb/article/219/9/e201912144/151863/Critical-role-of-mitochondrial-ubiquitination-and
  55. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling
    1
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      TBK1

      DOI: 10.1111/jcmm.15774

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    pubmed.ncbi.nlm.nih.gov/32858764/
  56. Jan 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.celrep.2019.03.098

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    sciencedirect.com/science/article/pii/S2211124719304371
  58. Nov 2018
  59. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    sciencedirect.com/science/article/pii/S0092867418309693
  60. Nov 2017
  61. www.sciencedirect.com www.sciencedirect.com
    Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells
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