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Aug 2026
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AAV-DJ enables efficient, function-preserving neuronal transduction for circuit interrogation in human cortical and thalamic organoids

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Jul 2026
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Protocol for the generation of human medullary spinal trigeminal nucleus-like organoids and trigeminothalamic assembloids

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Mar 2026
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ROME, an Ancient Gene with a Novel Function in Vertebrates, Is a Key Modulator of Embryonal Development and Cancer Metastasis

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pmc.ncbi.nlm.nih.gov/articles/PMC13012068/
Feb 2026
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Injury-transduced SerpinOLs modulate neuroinflammation and glial activation in the diseased and non-diseased CNS

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  DOI: 10.64898/2026.01.29.702669
  
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biorxiv.org/content/10.64898/2026.01.29.702669v2
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Dispensable regulation of brain development and myelination by the immune-related protein Serpina3n

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pmc.ncbi.nlm.nih.gov/articles/PMC11810613/
Jan 2026
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Generation of human pineal gland organoids with melatonin production for disease modeling

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  DOI: 10.1016/j.stem.2025.12.004
  
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May 2025
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Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines

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1. scibot 18 May 2025
  
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Feb 2025
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CCN6 suppresses metaplastic breast carcinoma by antagonizing WNT/β-catenin signaling to inhibit EZH2-driven EMT

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  DOI: 10.1158/0008-5472.CAN-23-4054
  
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aacrjournals.org/cancerres/article/84/19/3235/748708/CCN6-Suppresses-Metaplastic-Breast-Carcinoma-by
Jan 2025
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A niche-dependent redox rheostat regulates epithelial stem cell fate in the distal colon

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1. scibot 31 Jan 2025
  
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52.53.155.43/79f18ee8720d66564852d009166058cb2d19618c/PDF-html.html
Dec 2024
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BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells

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  DOI: 10.1038/s44318-024-00276-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11612440/
Nov 2024
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Epigenetic control of myogenic identity of human muscle stem cells in Duchenne muscular dystrophy

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1. scibot 24 Nov 2024
  
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sciencedirect.com/science/article/pii/S2589004224025756
Jul 2024
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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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sciencedirect.com/science/article/pii/S2211124724008611
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Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114414
  
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Synaptic plasticity in human thalamocortical assembloids

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  DOI: 10.1016/j.celrep.2024.114503
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11407288/
Apr 2024
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Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

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  DOI: 10.1016/j.celrep.2024.114065
  
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Mar 2024
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Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders

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Feb 2024
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Dispensable regulation of brain development and myelination by Serpina3n

1
1. scibot 15 Feb 2024
  
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  DOI: 10.1101/2024.02.06.579239
  
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biorxiv.org/content/10.1101/2024.02.06.579239v1
Dec 2023
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Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin

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sciencedirect.com/science/article/pii/S2211124723015231
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Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain

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sciencedirect.com/science/article/pii/S0092867423012333
Nov 2023
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Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling

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Sep 2023
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3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages

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Apr 2023
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Generation of ventralized human thalamic organoids with thalamic reticular nucleus

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sciencedirect.com/science/article/pii/S1934590923000784
Mar 2023
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Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma

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Aug 2022
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SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells

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sciencedirect.com/science/article/pii/S2211124722010658
Feb 2022
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Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2

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Oct 2021
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PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination

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Sep 2021
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TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state

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Jul 2021
europepmc.org europepmc.org

TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.

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1. scibot 30 Jul 2021
  
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  DOI: 10.7554/eLife.23242
  
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europepmc.org/articles/PMC5438253/
Jun 2021
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Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development

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Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction

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ncbi.nlm.nih.gov/pmc/articles/PMC8184503/
May 2021
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ZC3H4 restricts non-coding transcription in human cells

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ncbi.nlm.nih.gov/pmc/articles/PMC8137146/
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The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

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  DOI: 10.1523/JNEUROSCI.2386-20.2021
  
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jneurosci.org/content/41/8/1650
Mar 2021
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A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells

1
1. scibot 09 Mar 2021
  
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  DOI: 10.7554/eLife.64444
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7924951/
Sep 2020
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GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation

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  DOI: 10.1016/j.celrep.2020.107540
  
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Generation of Regionally Specified Human Brain Organoids Resembling Thalamus Development

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  DOI: 10.1016/j.xpro.2019.100001
  
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sciencedirect.com/science/article/pii/S2666166719300012
Jan 2020
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Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination

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  DOI: 10.1016/j.celrep.2019.09.020
  
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sciencedirect.com/science/article/pii/S2211124719311970
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Untitled document

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  DOI: 10.1016/j.celrep.2018.12.059
  
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sciencedirect.com/science/article/pii/S2211124718320047
Nov 2018
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The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord

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1. scibot 05 Nov 2018
  
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link.springer.com/article/10.1007/s12035-018-1035-7
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A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

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Sox2 is essential for oligodendroglial proliferation and differentiation during postnatal brain myelination and CNS remyelination

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