30 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Lysine deacetylation inhibition reverses TDP-43 mislocalization and in combination with arimoclomol ameliorates neuromuscular pathology
    1
    1. scibot 21 Dec 2024
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      DOI: 10.1101/2024.12.15.628528

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    biorxiv.org/content/10.1101/2024.12.15.628528v1
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of small molecule inhibitors of G3BP-driven stress granule formation
    1
    1. scibot 30 Jul 2024
      RRID:AB_2200505

      DOI: 10.1083/jcb.202308083

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    ncbi.nlm.nih.gov/pmc/articles/PMC10824102/
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons
    2
    1. scibot 29 Feb 2024
      RRID:AB_2200505

      DOI: 10.1016/j.isci.2024.109166

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    2. scibot 29 Feb 2024
      RRID:AB_2200505

      DOI: 10.1016/j.isci.2024.109166

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    sciencedirect.com/science/article/pii/S2589004224003870
  7. www.sciencedirect.com www.sciencedirect.com
    Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice
    1
    1. scibot 16 Feb 2024
      RRID:AB_2200505

      DOI: 10.1016/j.neuron.2024.01.022

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    sciencedirect.com/science/article/pii/S0896627324000485
  8. Sep 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of the Progranulin-driven Autophagy-lysosomal Pathway Mediates Secretion of the Nuclear Protein TDP-43
    1
    1. scibot 30 Sep 2023
      RRID:AB_2200505

      DOI: 10.1016/j.jbc.2023.105272

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    sciencedirect.com/science/article/pii/S0021925823023001
  10. Jul 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
    1
    1. scibot 22 Jul 2023
      RRID:AB_2200505

      DOI: 10.1016/j.neuron.2023.06.019

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    sciencedirect.com/science/article/pii/S0896627323004786
  12. Jun 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 24 Jun 2023
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      DOI: 10.12688/f1000research.131852.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10285334/
  14. Feb 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
    1
    1. scibot 15 Feb 2023
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      DOI: 10.3233/ADR-220056

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    ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
  16. May 2022
  17. www.sciencedirect.com www.sciencedirect.com
    BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43
    1
    1. scibot 05 May 2022
      RRID:AB_2200505

      DOI: 10.1016/j.isci.2022.104273

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    sciencedirect.com/science/article/pii/S2589004222005430
  18. Jan 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis
    1
    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.neuron.2021.12.019

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    sciencedirect.com/science/article/pii/S0896627321010369
  20. academic.oup.com academic.oup.com
    Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia
    1
    1. scibot 04 Jan 2022
      RRID:AB_2200505

      DOI: 10.1093/brain/awab333

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    academic.oup.com/brain/article/144/12/3710/6491324
  21. Aug 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
    1
    1. scibot 28 Aug 2021
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      DOI: 10.1016/j.molcel.2021.07.038

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    sciencedirect.com/science/article/pii/S1097276521006225
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis
    1
    1. scibot 16 Aug 2021
      RRID:AB_2200505

      DOI: 10.1186/s13024-021-00470-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8353748/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 10 Aug 2021
      RRID:AB_2200505

      DOI: 10.1186/s12929-018-0479-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC6223059/
  25. www.sciencedirect.com www.sciencedirect.com
    Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
    1
    1. scibot 08 Aug 2021
      RRID:AB_2200505

      DOI: 10.1016/j.molcel.2017.02.013

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    sciencedirect.com/science/article/pii/S1097276517301284
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
    1
    1. scibot 03 Aug 2021
      RRID:AB_2200505

      DOI: 10.1016/j.molcel.2017.02.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5364369/
  27. Jul 2021
  28. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    Untitled document
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    1. scibot 29 Jul 2021
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      DOI: 10.1186/s12929-018-0479-4

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    jbiomedsci.biomedcentral.com/articles/10.1186/s12929-018-0479-4
  29. www.sciencedirect.com www.sciencedirect.com
    Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
    1
    1. scibot 27 Jul 2021
      AB_2200505

      DOI: 10.1016/j.molcel.2017.02.013

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      RRIDCUR:Unrecognized RRID:AB_2200505
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    sciencedirect.com/science/article/pii/S1097276517301284
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43
    1
    1. scibot 14 Jul 2021
      RRID:AB_2200505

      DOI: 10.1016/j.isci.2021.102733

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    ncbi.nlm.nih.gov/pmc/articles/PMC8259439/
  31. May 2021
  32. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Elevated GFAP isoform expression promotes protein aggregation and compromises astrocyte function
    1
    1. scibot 04 May 2021
      AB_2200505

      DOI: 10.1096/fj.202100087R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100087R
  33. Sep 2020
  34. link.springer.com link.springer.com
    RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases
    1
    1. scibot 23 Sep 2020
      RRID:AB_2200505

      DOI: 10.1186/s40478-020-00965-y

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      RRID:AB_2200505 RRIDCUR:Validated
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    link.springer.com/article/10.1186/s40478-020-00965-y
  35. www.sciencedirect.com www.sciencedirect.com
    BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain
    1
    1. scibot 13 Sep 2020
      RRID:AB_2200505

      DOI: 10.1016/j.cels.2020.03.003

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      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:AB_2200505
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    sciencedirect.com/science/article/pii/S2405471220301095
  36. Jan 2020
  37. www.nature.com www.nature.com
    C9-ALS/FTD-linked proline–arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2200505

      DOI: 10.1038/s41419-019-1983-5

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    nature.com/articles/s41419-019-1983-5
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
    1
    1. scibot 13 Jan 2020
      RRID:AB_2200505

      DOI: 10.7554/eLife.39578

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      Curator: @evieth

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      RRID:AB_2200505 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6426440/
  39. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
    1
    1. scibot 13 Jan 2020
      RRID:AB_2200505

      DOI: 10.1016/j.neuron.2019.02.038

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      Curator: @ethanbadger

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      RRID:AB_2200505 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319301734
  40. Nov 2018
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differential toxicity of TAR DNA‐binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells
    1
    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14465
  42. Nov 2017
  43. www.sciencedirect.com www.sciencedirect.com
    TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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      RRID:AB_2200505 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627317306475
  44. elifesciences.org elifesciences.org
    Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106
    2
    1. scibot 08 Nov 2017
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      Curator: @gabimpine

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      RRID:AB_2200505 RRIDCUR:Validated
    2. scibot 08 Nov 2017
      AB_2200505

      Curator: @chewbeccax

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    elifesciences.org/content/6/e19032