129 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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      DOI: 10.1158/0008-5472.CAN-24-1703

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  3. Dec 2024
  4. link.springer.com link.springer.com
    HIG-2 promotes glioma stemness and radioresistance mediated by IGFBP2-rich microparticles in hypoxia
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  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection
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      DOI: 10.1371/journal.ppat.1012663

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  6. Nov 2024
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    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
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    can-24-1703-html.html
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  9. Sep 2024
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  11. Aug 2024
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    Physical exercise mediates cortical synaptic protein lactylation to improve stress resilience
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    sciencedirect.com/science/article/pii/S1550413124002894
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    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
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    TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell
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  15. Jul 2024
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    Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation
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    Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis
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    The protective effects of Axitinib on blood-brain barrier dysfunction and ischemia-reperfusion injury in acute ischemic stroke
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    1. scibot 10 Jul 2024
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ROS are required for the germinative cell proliferation and metacestode larval growth of Echinococcus multilocularis
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    1. scibot 03 Jul 2024
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  20. Jun 2024
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    Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER
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    1. scibot 21 Jun 2024
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  22. May 2024
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    Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model
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  24. www.cell.com www.cell.com
    Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation
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    cell.com/cell-reports/fulltext/S2211-1247(24)00493-5
  25. Apr 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue
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    sciencedirect.com/science/article/pii/S2211124724004972
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    The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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  29. Mar 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices
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    sciencedirect.com/science/article/pii/S0092867424002538
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    Molecular determinants and signaling effects of PKA RIα phase separation
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    sciencedirect.com/science/article/pii/S1097276524001849
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development
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    sciencedirect.com/science/article/pii/S2211124724002456
  34. Feb 2024
  35. www.sciencedirect.com www.sciencedirect.com
    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
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    sciencedirect.com/science/article/pii/S2211124724001207
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    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
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    sciencedirect.com/science/article/pii/S1097276524000078
  37. Jan 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
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    HSP70 binds to specific non-coding RNA and regulates human RNA polymerase III
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
  42. Dec 2023
  43. aacrjournals.org aacrjournals.org
    Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
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      DOI: 10.1158/0008-5472.CAN-22-2108

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    aacrjournals.org/cancerres/article/82/24/4586/711513/Dormant-SOX9-Positive-Cells-Facilitate-MYC-Driven
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    Dapagliflozin protects against chronic heart failure in mice by inhibiting macrophage-mediated inflammation, independent of SGLT2
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    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
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  46. Nov 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice
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    sciencedirect.com/science/article/abs/pii/S2451945623003392
  48. Oct 2023
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of SELENOF translation by eIF4a3: Possible role in prostate cancer progression
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      DOI: 10.1002/mc.23616

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    onlinelibrary.wiley.com/doi/10.1002/mc.23616
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    LncRNA CFRL aggravates cardiac fibrosis by modulating both miR-3113-5p/CTGF and miR-3473d/FN1 axis
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    sciencedirect.com/science/article/pii/S2589004223021168
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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      DOI: 10.1016/j.celrep.2023.113180

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    sciencedirect.com/science/article/pii/S2211124723011920
  53. Sep 2023
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Guanosine increases global SUMO1-ylation in the hippocampus of young and aged mice and improves the short-term memory of young mice
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      DOI: 10.1111/jnc.15920

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15920
  55. Jul 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
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  57. Jun 2023
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    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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  59. May 2023
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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  61. Apr 2023
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    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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    Optogenetic Activation of UCP1-Dependent Thermogenesis in Brown Adipocytes
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
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    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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    Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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  117. academic.oup.com academic.oup.com
    Impact of pregnancy and lactation on the long-term regulation of energy balance in female mice
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  119. May 2021
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    Iterative tomography with digital adaptive optics permits hour-long intravital observation of 3D subcellular dynamics at millisecond scale
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  122. Apr 2021
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    Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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      rabbit anti-β-Tubulin

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    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
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    The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
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    Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
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    Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
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  129. Feb 2021
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    Activation of ovarian taste receptors inhibits progesterone production potentially via NO/cGMP and apoptotic signaling
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    STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer
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  132. Jan 2021
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    Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers
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  134. Dec 2020
  135. molmed.biomedcentral.com molmed.biomedcentral.com
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  136. Sep 2020
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    SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
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    HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
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    Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons
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    Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
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  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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      β-tubulin

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  146. Jan 2020
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    DLK mediates the neuronal intrinsic immune response and regulates glial reaction and neuropathic pain
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    Involvement of Akt-dependent CREB signaling pathway in hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-induced early growth response protein-1 (Egr-1) expression in vascular smooth muscle cells - Canadian Journal of Physiology and Pharmacology
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    Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury
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    Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21
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    Nuclear AGO1 Regulates Gene Expression by Affecting Chromatin Architecture in Human Cells
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    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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    Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
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    Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma
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    12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
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    Protein kinase B mediates insulin‐like growth factor 1‐induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells
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    Mitochondria‐coupled glucose phosphorylation develops after birth to modulate H2O2 release and calcium handling in rat brain
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    Lysosome Positioning Influences mTORC2 and AKT Signaling
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    sciencedirect.com/science/article/pii/S1097276519303624
  162. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      AB_2210545

      DOI: 10.1016/j.devcel.2019.02.023

      Resource: (Cell Signaling Technology Cat# 2146, RRID:AB_2210545)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1534580719301467
  163. Nov 2018
  164. www.sciencedirect.com www.sciencedirect.com
    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
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    1. scibot 05 Nov 2018
      RRID:AB_2210545

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    sciencedirect.com/science/article/pii/S2211124718309835
  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chemical hypoxia‐induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (NRF2)
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      RRID:AB_2210545

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14270/full
  166. academic.oup.com academic.oup.com
    Region-Specific Suppression of Hypothalamic Responses to Insulin To Adapt to Elevated Maternal Insulin Secretion During Pregnancy
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    1. scibot 05 Nov 2018
      AB_2210545

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    academic.oup.com/endo/article/158/12/4257/4283042
  167. academic.oup.com academic.oup.com
    Reestablishment of Energy Balance in a Male Mouse Model With POMC Neuron Deletion of BMPR1A
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    1. scibot 05 Nov 2018
      AB_2210545

      Curator: @evieth

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    academic.oup.com/endo/article/158/12/4233/4364937
  168. Nov 2017
  169. www.sciencedirect.com www.sciencedirect.com
    The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity
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    1. scibot 08 Nov 2017
      RRID:AB_2210545

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1550413117304886
  170. academic.oup.com academic.oup.com
    Inflammatory Stimuli Increase Progesterone Receptor-A Stability and Transrepressive Activity in Myometrial Cells
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    1. scibot 08 Nov 2017
      AB_2210545

      Curator: @bandrow

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    academic.oup.com/endo/article/158/1/158/2751116/Inflammatory-Stimuli-Increase-Progesterone
  171. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STIM‐1 and ORAI‐1 channel mediate angiotensin‐II‐induced expression of Egr‐1 in vascular smooth muscle cells
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    1. scibot 08 Nov 2017
      AB_2210545

      Curator: @Zeljana_Babic

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    onlinelibrary.wiley.com/wol1/doi/10.1002/jcp.25810/full
  172. elifesciences.org elifesciences.org
    Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors
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    1. scibot 08 Nov 2017
      β-tubulin

      Curator: @gabimpine

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      RRID:AB_2210545 RRIDCUR:Missing
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    elifesciences.org/content/3/e04037