124 Matching Annotations
  1. Last 7 days
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    Inhibition of serine racemase prevents diabetic retinopathy
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    1. scibot 16 Jul 2024
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    biorxiv.org/content/10.1101/2024.06.30.601441v1
  3. Jul 2024
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    Polymerization of ZBTB transcription factors regulates chromatin occupancy
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    sciencedirect.com/science/article/pii/S1097276524005136
  5. Jun 2024
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    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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    cell.com/iscience/abstract/S2589-0042(24)01293-8
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    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
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    sciencedirect.com/science/article/pii/S0092867424005786
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    p38 MAPK activation and STIM1-Orai3 association mediate TRPC6 externalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC10228675/
  10. May 2024
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    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
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    Vaccinia virus subverts xenophagy through phosphorylation and nuclear targeting of p62
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  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16397

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16397
  14. Apr 2024
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    Genetics of cystogenesis in base-edited human organoids reveal therapeutic strategies for polycystic kidney disease
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    sciencedirect.com/science/article/pii/S1934590924000869
  16. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
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    1. scibot 16 Mar 2024
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      DOI: 10.21203/rs.3.rs-3938716/v1

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  20. Feb 2024
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    Variants in the first methionine of RAD51C are homologous recombination proficient due to an alternative start site
    1
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  22. Jan 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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  24. Oct 2023
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    Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase
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    sciencedirect.com/science/article/pii/S2212877823001503
  26. www.cell.com www.cell.com
    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
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    cell.com/iscience/abstract/S2589-0042(23)02087-4
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    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10521973/
  28. Sep 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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    ncbi.nlm.nih.gov/pmc/articles/PMC10509304/
  30. Aug 2023
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    Reduced mastication during growth inhibits cognitive function by affecting trigeminal ganglia and modulating Wnt signaling pathway and ARHGAP33 molecular transmission
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    sciencedirect.com/science/article/pii/S0143417923000513
  32. Jul 2023
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    Probing expression of E-selectin using CRISPR-Cas9-mediated tagging with HiBiT in human endothelial cells
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    sciencedirect.com/science/article/pii/S2589004223013093
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    Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
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    sciencedirect.com/science/article/pii/S2589004223012208
  35. Jun 2023
  36. www.sciencedirect.com www.sciencedirect.com
    SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas
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    sciencedirect.com/science/article/pii/S1931312823002111
  37. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
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    Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124723005922
  39. May 2023
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    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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    sciencedirect.com/science/article/pii/S1097276523003350
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    LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004223008313
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    LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation
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    sciencedirect.com/science/article/pii/S1097276523002885
  43. Apr 2023
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    The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
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    sciencedirect.com/science/article/pii/S1074761323001413
  45. Mar 2023
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    Structural features of the Notch ankyrin domain-Deltex WWE2 domain heterodimer determined by NMR spectroscopy and functional implications
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    sciencedirect.com/science/article/pii/S0969212623000795
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9988578/
  48. Feb 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5
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    ncbi.nlm.nih.gov/pmc/articles/PMC9938590/
  50. www.nature.com www.nature.com
    Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
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    nature.com/articles/s42003-023-04568-w
  51. Jan 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
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    sciencedirect.com/science/article/pii/S1550413122005770
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    Glutamine and leucine administration attenuates muscle atrophy in sepsis
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      DOI: 10.1016/j.lfs.2022.121327

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    sciencedirect.com/science/article/pii/S002432052201027X
  54. www.sciencedirect.com www.sciencedirect.com
    DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma
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      DOI: 10.1016/j.xcrm.2022.100880

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    sciencedirect.com/science/article/pii/S266637912200444X
  55. Dec 2022
  56. aacrjournals.org aacrjournals.org
    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
  57. Nov 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
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  113. Apr 2021
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  130. Oct 2020
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    BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
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    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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  144. Jan 2020
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    Protein arginine methyltransferase 1 interacts with PGC1α and modulates thermogenic fat activation
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      DOI: 10.1210/en.2019-00504

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    Glutamine Links Obesity to Inflammation in Human White Adipose Tissue
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    Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
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    Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells
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  156. Nov 2018
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    A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer
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    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
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    A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism
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    A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer
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    A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes
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    Maternal Low Protein Isocaloric Diet Suppresses Pancreatic β-Cell Proliferation in Mouse Offspring via miR-15b
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      Cell Signalling Technology; number 2144 

      Curator: @bandrow

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    Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
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      Curator: @Zeljana_Babic

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