115 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Genetics of cystogenesis in base-edited human organoids reveal therapeutic strategies for polycystic kidney disease
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      DOI: 10.1016/j.stem.2024.03.005

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    sciencedirect.com/science/article/pii/S1934590924000869
  3. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.chembiol.2024.02.013

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    sciencedirect.com/science/article/pii/S2451945624000874
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    1. scibot 28 Mar 2024
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      DOI: 10.1016/j.isci.2024.109288

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    ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
    1
    1. scibot 16 Mar 2024
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      DOI: 10.21203/rs.3.rs-3938716/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10925443/
  7. Feb 2024
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    Variants in the first methionine of RAD51C are homologous recombination proficient due to an alternative start site
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.dnarep.2024.103644

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    sciencedirect.com/science/article/pii/S156878642400020X
  9. Jan 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
    1
    1. scibot 23 Jan 2024
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      DOI: 10.1186/s13578-023-01179-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10800076/
  11. Oct 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.molmet.2023.101816

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    sciencedirect.com/science/article/pii/S2212877823001503
  13. www.cell.com www.cell.com
    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
    1
    1. scibot 07 Oct 2023
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      DOI: 10.1016/j.isci.2023.108010

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    cell.com/iscience/abstract/S2589-0042(23)02087-4
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.112845

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    ncbi.nlm.nih.gov/pmc/articles/PMC10521973/
  15. Sep 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
    1
    1. scibot 23 Sep 2023
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      DOI: 10.1016/j.isci.2023.107819

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    ncbi.nlm.nih.gov/pmc/articles/PMC10509304/
  17. Aug 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Reduced mastication during growth inhibits cognitive function by affecting trigeminal ganglia and modulating Wnt signaling pathway and ARHGAP33 molecular transmission
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.npep.2023.102370

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    sciencedirect.com/science/article/pii/S0143417923000513
  19. Jul 2023
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    Probing expression of E-selectin using CRISPR-Cas9-mediated tagging with HiBiT in human endothelial cells
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.isci.2023.107232

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    sciencedirect.com/science/article/pii/S2589004223013093
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    Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
    1
    1. scibot 01 Jul 2023
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      DOI: 10.1016/j.isci.2023.107143

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    sciencedirect.com/science/article/pii/S2589004223012208
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.chom.2023.05.018

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    sciencedirect.com/science/article/pii/S1931312823002111
  24. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  25. www.sciencedirect.com www.sciencedirect.com
    Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112581

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    sciencedirect.com/science/article/pii/S2211124723005922
  26. May 2023
  27. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
    1
    1. scibot 31 May 2023
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      DOI: 10.1016/j.molcel.2023.05.011

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    sciencedirect.com/science/article/pii/S1097276523003350
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    LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.isci.2023.106754

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    sciencedirect.com/science/article/pii/S2589004223008313
  29. www.sciencedirect.com www.sciencedirect.com
    LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.molcel.2023.04.017

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    sciencedirect.com/science/article/pii/S1097276523002885
  30. Apr 2023
  31. www.sciencedirect.com www.sciencedirect.com
    The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.immuni.2023.03.021

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    sciencedirect.com/science/article/pii/S1074761323001413
  32. Mar 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Structural features of the Notch ankyrin domain-Deltex WWE2 domain heterodimer determined by NMR spectroscopy and functional implications
    1
    1. scibot 28 Mar 2023
      RRID:AB_221054

      DOI: 10.1016/j.str.2023.03.003

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    sciencedirect.com/science/article/pii/S0969212623000795
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.isci.2023.106161

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    ncbi.nlm.nih.gov/pmc/articles/PMC9988578/
  35. Feb 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5
    1
    1. scibot 23 Feb 2023
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      DOI: 10.1186/s13072-023-00481-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC9938590/
  37. www.nature.com www.nature.com
    Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
    4
    1. scibot 18 Feb 2023
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      DOI: 10.1038/s42003-023-04568-w

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    nature.com/articles/s42003-023-04568-w
  38. Jan 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
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    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.cmet.2022.12.014

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    sciencedirect.com/science/article/pii/S1550413122005770
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    Glutamine and leucine administration attenuates muscle atrophy in sepsis
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    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.lfs.2022.121327

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    sciencedirect.com/science/article/pii/S002432052201027X
  41. www.sciencedirect.com www.sciencedirect.com
    DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.xcrm.2022.100880

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    sciencedirect.com/science/article/pii/S266637912200444X
  42. Dec 2022
  43. aacrjournals.org aacrjournals.org
    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
    1
    1. scibot 04 Dec 2022
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
  44. Nov 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
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      DOI: 10.1016/j.devcel.2022.10.008

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    sciencedirect.com/science/article/pii/S1534580722007602
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    Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
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    sciencedirect.com/science/article/pii/S2589004222016765
  47. www.sciencedirect.com www.sciencedirect.com
    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
    1
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    sciencedirect.com/science/article/pii/S1097276522009625
  48. Oct 2022
  49. 52.53.155.43 52.53.155.43
    mcr-22-0040-html.html
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    52.53.155.43/727478f306d650986e0e949733013801988f63e4/mcr-22-0040-html.html
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells
    1
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      DOI: 10.3389/fcvm.2022.979745

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    ncbi.nlm.nih.gov/pmc/articles/PMC9561411/
  51. Jun 2022
  52. www.sciencedirect.com www.sciencedirect.com
    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
    1
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      DOI: 10.1016/j.celrep.2022.110889

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    sciencedirect.com/science/article/pii/S2211124722006647
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    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
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      DOI: 10.1016/j.neuron.2022.05.009

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    sciencedirect.com/science/article/pii/S0896627322004500
  54. May 2022
  55. www.sciencedirect.com www.sciencedirect.com
    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
    1
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      DOI: 10.1016/j.devcel.2022.04.020

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    sciencedirect.com/science/article/pii/S1534580722003069
  56. Apr 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
    1
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    sciencedirect.com/science/article/pii/S1097276522002647
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    The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
    1
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      DOI: 10.1016/j.isci.2022.104089

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    PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites
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    Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes
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    Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon
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  113. Dec 2020
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    Overexpression of d -amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats
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    Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
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    A novel HDAC6 inhibitor improves myelination of Schwann cells in a model of Charcot‐Marie‐Tooth disease type 1A
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  117. Oct 2020
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    Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease
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  119. Sep 2020
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    BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
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    Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit
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    Vascular smooth muscle cell phenotypic transition regulates gap junctions of cardiomyocyte
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    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection
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    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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    ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at PM-ER contact sites
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  131. Jan 2020
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    Protein arginine methyltransferase 1 interacts with PGC1α and modulates thermogenic fat activation
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      DOI: 10.1210/en.2019-00504

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    Sleep deprivation impairs learning and memory by decreasing protein O‐GlcNAcylation in the brain of adult zebrafish
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      DOI: 10.1096/fj.201901399RR

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    Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
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    21-benzylidene digoxin decreases proliferation by inhibiting the egfr/erk signaling pathway and induces apoptosis in hela cells
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      DOI: 10.1016/j.steroids.2019.108551

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    Glutamine Links Obesity to Inflammation in Human White Adipose Tissue
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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
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    Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
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      DOI: 10.1016/j.molcel.2019.07.034

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      DOI: 10.1210/en.2018-00881

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    Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells
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  143. Nov 2018
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    A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer
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    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
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    A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism
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    A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer
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    A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes
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    Maternal Low Protein Isocaloric Diet Suppresses Pancreatic β-Cell Proliferation in Mouse Offspring via miR-15b
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      Cell Signalling Technology; number 2144 

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    Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
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