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Sep 2025
www.biorxiv.org www.biorxiv.org

The axonal ER couples translation and secretion machineries for local delivery of axonal transmembrane proteins to promote axonal development

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  DOI: 10.1101/2025.09.09.674816
  
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biorxiv.org/content/10.1101/2025.09.09.674816v1
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α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation

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  DOI: 10.1016/j.molcel.2025.08.022
  
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sciencedirect.com/science/article/pii/S1097276525007075
Aug 2025
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Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis

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  DOI: 10.1016/j.celrep.2025.116174
  
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sciencedirect.com/science/article/pii/S2211124725009453
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YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116188
  
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sciencedirect.com/science/article/pii/S2211124725009593
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Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116137
  
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sciencedirect.com/science/article/pii/S2211124725009088
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1-s2.0-S001448862500281X-main-html.html

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1. scibot 12 Aug 2025
  
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  DOI: 10.1016/j.expneurol.2025.115417
  
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52.53.155.43/0608c764eb20af0dc42608bac19e92db6c060608/1-s2.0-S001448862500281X-main-html.html
52.53.155.43 52.53.155.43

1-s2.0-S001448862500281X-main-html.html

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1. scibot 08 Aug 2025
  
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52.53.155.43/4666e123f5d79bd0abda45c8eef4241d5f83ef67/1-s2.0-S001448862500281X-main-html.html
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2025.07.29.667421v1.full-html.html

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1. scibot 05 Aug 2025
  
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  DOI: 10.1101/2025.07.29.667421
  
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52.53.155.43/b596bd38105568fb5cf99ba7e532b5190556003c/2025.07.29.667421v1.full-html.html
Jul 2025
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Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115961
  
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sciencedirect.com/science/article/pii/S2211124725007326
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Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.007
  
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sciencedirect.com/science/article/pii/S1534580725003624
Jun 2025
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Lymph node fibroblast phenotypes and immune crosstalk regulated by podoplanin activity

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115908
  
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sciencedirect.com/science/article/pii/S2211124725006795
www.jneurosci.org www.jneurosci.org

Specializations in amygdalar and hippocampal innervation of the primate nucleus accumbens shell

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1. scibot 26 Jun 2025
  
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  DOI: 10.1523/JNEUROSCI.2425-24.2025
  
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jneurosci.org/content/45/24/e2425242025
www.cell.com www.cell.com

Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity

1
1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115809
  
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cell.com/cell-reports/abstract/S2211-1247(25)00580-7
May 2025
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A critical role of Neuroligin 2 C-terminus in OCD and social behavior

1
1. scibot 30 May 2025
  
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  DOI: 10.1523/JNEUROSCI.1417-24.2025
  
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jneurosci.org/content/45/19/e1417242025
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Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo

1
1. scibot 18 May 2025
  
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  DOI: 10.1016/j.neuron.2025.04.010
  
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sciencedirect.com/science/article/pii/S0896627325002934
Mar 2025
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Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism

1
1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.cmet.2025.02.008
  
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sciencedirect.com/science/article/pii/S155041312500066X
Jan 2025
www.nature.com www.nature.com

Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium

1
1. scibot 30 Jan 2025
  
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  Thermo Fisher A-31556
  
  DOI: 10.1038/s41556-023-01116-w
  
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nature.com/articles/s41556-023-01116-w
Nov 2024
www.biorxiv.org www.biorxiv.org

Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors

1
1. scibot 28 Nov 2024
  
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  DOI: 10.1101/2024.11.23.624963
  
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biorxiv.org/content/10.1101/2024.11.23.624963v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dual inhibition of aminoacyl-tRNA synthetase interacting multifunctional protein-2 and α-synuclein by steroid derivative is neuroprotective in Parkinson’s model

1
1. scibot 26 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111165
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11576395/
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Impairment of the glial phagolysosomal system drives prion-like propagation in a Drosophila model of Huntington's disease

1
1. scibot 21 Nov 2024
  
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  DOI: 10.1523/JNEUROSCI.1256-23.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11097281/
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Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus

1
1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114978
  
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sciencedirect.com/science/article/pii/S2211124724013299
Sep 2024
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Activation of the NLRP1B inflammasome by caspase-8

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1038/s42003-024-06882-3
  
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nature.com/articles/s42003-024-06882-3
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Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation

1
1. scibot 25 Sep 2024
  
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  RRID:AB_221604
  
  DOI: 10.1016/j.devcel.2020.01.011
  
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sciencedirect.com/science/article/pii/S1534580720300125
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Untitled document

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1. scibot 25 Sep 2024
  
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  DOI: 10.1002/glia.23580
  
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onlinelibrary.wiley.com/doi/full/10.1002/glia.23580
Aug 2024
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Developmental shaping of node of Ranvier geometry contributes to spike timing maturation in primary auditory afferents

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114651
  
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sciencedirect.com/science/article/pii/S2211124724010027
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1038/s44318-024-00164-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
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The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114624
  
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sciencedirect.com/science/article/pii/S2211124724009744
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Disease-relevant upregulation of P2Y1 receptor in astrocytes enhances neuronal excitability via IGFBP2

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1. scibot 21 Aug 2024
  
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  DOI: 10.1038/s41467-024-50190-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11310333/
52.53.155.43 52.53.155.43

woode-et-al-2024-increased-activity-of-epithelial-cdc42-rho-gtpase-and-tight-junction-permeability-in-the-cftr-knockout-html.html

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  DOI: 10.6084/m9.figshare.25766064.v1
  
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52.53.155.43/4f456d0d053c774e2d98a2ed774240b98cde2115/woode-et-al-2024-increased-activity-of-epithelial-cdc42-rho-gtpase-and-tight-junction-permeability-in-the-cftr-knockout-html.html
Jul 2024
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Respiratory infection with influenza A virus delays remyelination and alters oligodendrocyte metabolism

1
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  AB_221605
  
  DOI: 10.1016/j.isci.2024.110464
  
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sciencedirect.com/science/article/pii/S2589004224016894
www.embopress.org www.embopress.org

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

2
1. scibot 12 Jul 2024
  
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  AB_221605
  
  DOI: 10.1038/s44318-024-00164-8
  
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2. scibot 12 Jul 2024
  
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  DOI: 10.1038/s44318-024-00164-8
  
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embopress.org/doi/10.1038/s44318-024-00164-8
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke

1
1. scibot 14 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110031
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11167442/
May 2024
52.53.155.43 52.53.155.43

Non-apoptotic caspase events and Atf3 expression underlie direct neuronal differentiation of adult neural stem cells

2
1. scibot 29 May 2024
  
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  RRID:AB_221605
  
  DOI: 10.1101/2024.03.09.584233
  
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2. scibot 29 May 2024
  
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  RRID:AB_221605
  
  DOI: 10.1101/2024.03.09.584233
  
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52.53.155.43/2b92d11b8fe97a4914ca774f880354d9ae603ad1/2024.03.09.584233v1.full-html.html
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Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons

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Transient sensorimotor projections in the developmental song learning period

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Spatiotemporal Mapping and Molecular Basis of Whole-brain Circuit Maturation

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The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex

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The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex

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JNEUROSCI.1256-23.2024.full-html.html

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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

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Restoring vision in adult amblyopia by enhancing plasticity through deletion of the transcriptional repressor REST

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BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing

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Rab32 family proteins regulate autophagosomal components recycling

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Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells

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Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice

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Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo

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ULK phosphorylation of STX17 controls autophagosome maturation via FLNA

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Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development

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Human REM sleep recalibrates neural activity in support of memory formation

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GABAergic-like dopamine synapses in the brain

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Functional architecture of dopamine neurons driving fear extinction learning

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Molecular basis of interactions between CaMKII and α-actinin-2 that underlie dendritic spine enlargement

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Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling

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Human REM sleep recalibrates neural activity in support of memory formation

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Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice

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GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells

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Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis

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Belly roll, a GPI-anchored Ly6 protein, regulates Drosophila melanogaster escape behaviors by modulating the excitability of nociceptive peptidergic interneurons

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Multiplex translaminar imaging in the spinal cord of behaving mice

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Trans-segmental imaging in the spinal cord of behaving mice

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Feb 2023
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Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression

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Secretin receptor deletion in the subfornical organ attenuates the activation of excitatory neurons under dehydration

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Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

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The disconnect2 mutation disrupts the tjp1b gene that is required for electrical synapse formation

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  DOI: 10.17912/micropub.biology.000593
  
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Jun 2022
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Electro-optical mechanically flexible coaxial microprobes for minimally invasive interfacing with intrinsic neural circuits

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May 2022
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Mapping brain-wide excitatory projectome of primate prefrontal cortex at submicron resolution and comparison with diffusion tractography

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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

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NanoDam identifies Homeobrain (ARX) and Scarecrow (NKX2.1) as conserved temporal factors in the Drosophila central brain and visual system

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Vinculin controls endothelial cell junction dynamics during vascular lumen formation

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Macrophage network dynamics depend on haptokinesis for optimal local surveillance

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Developmentally regulated impairment of parvalbumin interneuron synaptic transmission in an experimental model of Dravet syndrome

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Pathways for memory, cognition and emotional context: hippocampal, subgenual area 25 and amygdalar axons show unique interactions in the primate thalamic Reuniens Nucleus

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Hypothalamic Galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop

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Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization

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The anterior cingulate cortex and its role in controlling contextual fear memory to predatory threats

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TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits

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Identification of a therapeutic interfering particle—A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance

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Parahippocampal latrophilin-2 (ADGRL2) expression controls topographical presubiculum to entorhinal cortex circuit connectivity

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Phagocytic ‘teeth’ and myosin-II ‘jaw’ power target constriction during phagocytosis

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Axonal CB1 receptors mediate inhibitory bouton formation via cAMP increase and PKA

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Acute brain vascular regeneration occurs via lymphatic transdifferentiation

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AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke

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An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens

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ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability

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Amygdala microglia modify neuronal plasticity via complement C1q/C3-CR3 signaling and contribute to visceral pain in a rat model

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Untitled document

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Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

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Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity

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Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks

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Dissection, in vivo imaging and analysis of the mouse epitrochleoanconeus muscle

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Cell-type specific dynamics of calcium activity in cortical circuits over the course of slow wave sleep and rapid eye movement sleep

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Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia

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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

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Electrical synaptic transmission requires a postsynaptic scaffolding protein

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SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis

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Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice

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Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain

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Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence

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High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons

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Anoctamin 2-chloride channels reduce simple spike activity and mediate inhibition at elevated calcium concentration in cerebellar Purkinje cells

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Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites

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TPH2 in the dorsal Raphe nuclei regulates energy balance in a sex-dependent manner

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scRNA-sequencing reveals new enteric nervous system roles for GDNF, NRTN, and TBX3

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Isolation of human ESC-derived cardiac derivatives and embryonic heart cells for population and single-cell RNA-seq analysis

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Live Imaging Reveals Listeria Hijacking of E-Cadherin Recycling as It Crosses the Intestinal Barrier

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A circuit of mossy cells controls the efficacy of memory retrieval by Gria2I inhibition of Gria2

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NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation

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An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism

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A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

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Super-Resolution Microscopy and FIB-SEM Imaging Reveal Parental Centriole-Derived, Hybrid Cilium in Mammalian Multiciliated Cells

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Pathways for Contextual Memory: The Primate Hippocampal Pathway to Anterior Cingulate Cortex

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Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels

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Increase of leucocyte-derived extracellular traps (ETs) in semen samples from human acute epididymitis patients—a pilot study

1
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Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation

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The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation

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Genetic transformation of the dinoflagellate chloroplast

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Heterogeneous fate choice of genetically modulated adult neural stem cells in gray and white matter of the central nervous system

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Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network

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Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK

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Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS

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Characterization of Button Loci that Promote Homologous Chromosome Pairing and Cell-Type-Specific Interchromosomal Gene Regulation

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Cell-Size Pleomorphism Drives Aberrant Clone Dispersal in Proliferating Epithelia

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Feedback-Driven Assembly of the Axon Initial Segment

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Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity

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Untitled document

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Untitled document

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Untitled document

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Involvement of aquaporin‐4 in laminin‐enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and α‐syntrophin in aquaporin‐4 expression

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Untitled document

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Cyclophilin D regulates neuronal activity‐induced filopodiagenesis by fine‐tuning dendritic mitochondrial calcium dynamics

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_221605
  
  DOI: 10.1111/jnc.14484
  
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Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium

1
1. scibot 12 Jan 2020
  
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  RRID:AB_221605
  
  DOI: 10.1016/j.devcel.2019.04.034
  
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Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_221605
  
  DOI: 10.1016/j.neuron.2019.01.030
  
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_221605
  
  DOI: 10.1016/j.devcel.2019.01.007
  
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Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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In Vivo Regulation of Oligodendrocyte Precursor Cell Proliferation and Differentiation by the AMPA-Receptor Subunit GluA2

1
1. scibot 05 Nov 2018
  
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  RRID:AB_221605
  
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Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_221605
  
  Curator: @evieth
  
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Dynamic Architecture of DNA Repair Complexes and the Synaptonemal Complex at Sites of Meiotic Recombination

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1. scibot 05 Nov 2018
  
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Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons

1
1. scibot 05 Nov 2018
  
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  Alexa 405 goat anti-rabbit
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5746342/
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Cortical Connections Position Primate Area 25 as a Keystone for Interoception, Emotion, and Memory

1
1. scibot 05 Nov 2018
  
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Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development

1
1. scibot 05 Nov 2018
  
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  RRID:AB_221605
  
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Parvalbumin‐producing striatal interneurons receive excitatory inputs onto proximal dendrites from the motor thalamus in male mice

1
1. scibot 05 Nov 2018
  
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  AB_221605
  
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Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3

1
1. scibot 05 Nov 2018
  
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  AB_221605
  
  Curator: @evieth
  
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Asymmetry of an Intracellular Scaffold at Vertebrate Electrical Synapses

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0960982217313143
Nov 2017
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Nanoscale Visualization of Biomineral Formation in Coral Proto-Polyps

1
1. scibot 08 Nov 2017
  
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  RRID:AB_221605
  
  Curator: @Jmenke
  
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Synaptic Mechanisms of Feature Coding in the Visual Cortex of Awake Mice

1
1. scibot 08 Nov 2017
  
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  RRID:AB_221605
  
  Curator: @Jmenke
  
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An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division

1
1. scibot 08 Nov 2017
  
  in Public
  
  Cat# A-31556
  
  Curator: @Zeljana_Babic
  
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Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17

1
1. scibot 08 Nov 2017
  
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  AB_221605
  
  Curator: @chewbeccax
  
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Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres

1
1. scibot 08 Nov 2017
  
  in Public
  
  anti-Rabbit Alexa 405
  
  Curator: @kaitlinsung
  
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