58 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.neuron.2024.10.029

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    sciencedirect.com/science/article/pii/S0896627324008006
  3. Nov 2024
  4. elifesciences.org elifesciences.org
    Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells
    1
    1. scibot 07 Nov 2024
      AB_2218911

      DOI: 10.7554/eLife.89725

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    elifesciences.org/articles/89725
  5. Oct 2024
  6. aacrjournals.org aacrjournals.org
    YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1158/0008-5472.CAN-20-0025

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    aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
  7. Sep 2024
  8. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    1. scibot 13 Sep 2024
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      DOI: 10.1038/s41467-024-51831-7

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    nature.com/articles/s41467-024-51831-7
  9. Nov 2023
  10. www.sciencedirect.com www.sciencedirect.com
    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113486

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    sciencedirect.com/science/article/pii/S2211124723014985
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.stem.2023.09.015

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    sciencedirect.com/science/article/pii/S1934590923003624
  12. Jun 2023
  13. aacrjournals.org aacrjournals.org
    Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities
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    1. scibot 03 Jun 2023
      RRID:AB_2218911WB

      DOI: 10.1158/0008-5472.CAN-22-1577

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    aacrjournals.org/cancerres/article/83/6/890/718574/Olig1-2-Expressing-Intermediate-Lineage
  14. May 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development
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    1. scibot 06 May 2023
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      DOI: 10.1016/j.devcel.2023.04.011

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    sciencedirect.com/science/article/pii/S1534580723001818
  16. Mar 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate
    1
    1. scibot 04 Mar 2023
      RRID:AB_2218911

      DOI: 10.1016/j.cell.2023.02.010

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    sciencedirect.com/science/article/pii/S0092867423001277
  18. Dec 2022
  19. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 mediated approach to generate YAP-depleted human embryonic stem cell line (MUSIe002-A-1)
    1
    1. scibot 06 Dec 2022
      AB_2218911

      DOI: 10.1016/j.scr.2022.102990

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    sciencedirect.com/science/article/pii/S1873506122003397
  20. Nov 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
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    1. scibot 18 Nov 2022
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      DOI: 10.1016/j.molcel.2022.10.027

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    sciencedirect.com/science/article/pii/S1097276522010553
  22. Oct 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Opposing roles of ZEB1 in the cytoplasm and nucleus control cytoskeletal assembly and YAP1 activity
    1
    1. scibot 05 Oct 2022
      RRID:AB_2218911

      DOI: 10.1016/j.celrep.2022.111452

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    sciencedirect.com/science/article/pii/S2211124722012931
  24. Sep 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
    1
    1. scibot 08 Sep 2022
      RRID:AB_2218911

      DOI: 10.1016/j.celrep.2022.111313

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    sciencedirect.com/science/article/pii/S2211124722011378
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    Virtual screening for small-molecule pathway regulators by image-profile matching
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    1. scibot 07 Sep 2022
      RRID:AB_2218911

      DOI: 10.1016/j.cels.2022.08.003

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    sciencedirect.com/science/article/pii/S2405471222003301
  27. Jul 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
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    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.ccell.2022.06.006

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    sciencedirect.com/science/article/pii/S1535610822002707
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    Klf5 defines alveolar epithelial type 1 cell lineage commitment during lung development and regeneration
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    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.devcel.2022.06.007

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    sciencedirect.com/science/article/pii/S1534580722004476
  30. Jun 2022
  31. link.springer.com link.springer.com
    The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin
    1
    1. scibot 15 Jun 2022
      RRID:AB_2218911

      DOI: 10.1186/s12964-022-00843-1

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    link.springer.com/article/10.1186/s12964-022-00843-1
  32. www.sciencedirect.com www.sciencedirect.com
    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
    1
    1. scibot 03 Jun 2022
      RRID:AB_2218911

      DOI: 10.1016/j.ebiom.2022.104092

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    sciencedirect.com/science/article/pii/S2352396422002730
  33. Jan 2022
  34. www.sciencedirect.com www.sciencedirect.com
    YAP1 and PRDM14 converge to promote cell survival and tumorigenesis
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    1. scibot 06 Jan 2022
      RRID:AB_2218911

      DOI: 10.1016/j.devcel.2021.12.006

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    sciencedirect.com/science/article/pii/S1534580721009953
  35. Dec 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Yap-Myc signaling induces pancreatic stellate cell activation through regulating glutaminolysis
    1
    1. scibot 28 Dec 2021
      4912

      DOI: 10.1016/j.yexcr.2021.113000

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    sciencedirect.com/science/article/pii/S0014482721005565
  37. Nov 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
    1
    1. scibot 05 Nov 2021
      RRID:AB_2218911

      DOI: 10.7554/eLife.57462

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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  39. Oct 2021
  40. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Early resistance training-mediated stimulation of daily muscle protein synthetic responses to higher habitual protein intake in middle-aged adults
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    1. scibot 20 Oct 2021
      RRID:AB_2218911

      DOI: 10.1113/JP281907

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP281907
  41. Aug 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
      RRID:AB_2218911

      DOI: 10.1016/j.devcel.2018.11.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC6302147/
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    Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
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    1. scibot 09 Aug 2021
      RRID:AB_2218911

      DOI: 10.1016/j.cell.2018.11.012

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    sciencedirect.com/science/article/pii/S0092867418315046
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    Untitled document
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      DOI: 10.1016/j.devcel.2018.11.011

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    sciencedirect.com/science/article/pii/S1534580718309298
  45. Jul 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation
    1
    1. scibot 27 Jul 2021
      RRID:AB_10694682

      DOI: 10.1016/j.celrep.2019.05.005

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    sciencedirect.com/science/article/pii/S2211124719306163
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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
    1
    1. scibot 27 Jul 2021
      RRID:AB_10694682

      DOI: 10.1016/j.devcel.2018.12.021

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    sciencedirect.com/science/article/pii/S1534580718311171
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    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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    1. scibot 27 Jul 2021
      RRID:AB_10694682

      DOI: 10.1016/j.ccell.2018.06.002

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    sciencedirect.com/science/article/pii/S1535610818302307
  49. Jun 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
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    1. scibot 17 Jun 2021
      RRID:AB_2218911

      DOI: 10.1126/sciadv.abf9141

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    ncbi.nlm.nih.gov/pmc/articles/PMC8177709/
  51. May 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Copy number aberrations drive kinase rewiring, leading to genetic vulnerabilities in cancer
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    1. scibot 19 May 2021
      RRID:AB_2218911

      DOI: 10.1016/j.celrep.2021.109155

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    sciencedirect.com/science/article/pii/S2211124721004976
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Localized EMT reprograms glial progenitors to promote spinal cord repair
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      DOI: 10.1016/j.devcel.2021.01.017

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    sciencedirect.com/science/article/pii/S1534580721000757
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    A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease
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    1. scibot 14 Apr 2021
      RRID:AB_2218911

      DOI: 10.1016/j.cmet.2021.03.024

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    sciencedirect.com/science/article/pii/S1550413121001315
  56. Mar 2021
  57. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 Mar 2021
      RRID:AB_2218911

      DOI: 10.1111/bph.15378

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15378
  58. Feb 2021
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
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    1. scibot 09 Feb 2021
      RRID:AB_2218911

      DOI: 10.1016/j.jbc.2021.100386

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    ncbi.nlm.nih.gov/pmc/articles/PMC7948510/
  60. Sep 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt signaling contributes to withdrawal symptoms from opioid receptor activation induced by morphine exposure or chronic inflammation
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      RRID:AB_2218911

      DOI: 10.1097/j.pain.0000000000001738

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    ncbi.nlm.nih.gov/pmc/articles/PMC7351075/
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    Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair
    1
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      DOI: 10.1016/j.celrep.2020.107828

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    sciencedirect.com/science/article/pii/S2211124720308093
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    YAP-depleted iPSC MUSIi012-A-2 maintained all normal stem cell characteristics
    1
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      AB_2218911

      DOI: 10.1016/j.scr.2020.101723

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    sciencedirect.com/science/article/pii/S1873506120300271
  64. www.sciencedirect.com www.sciencedirect.com
    Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis
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      DOI: 10.1016/j.celrep.2020.107932

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    sciencedirect.com/science/article/pii/S221112472030913X
  65. elifesciences.org elifesciences.org
    Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade
    1
    1. scibot 10 Sep 2020
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      DOI: 10.7554/eLife.43996

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    elifesciences.org/articles/43996
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration
    1
    1. scibot 05 Sep 2020
      RRID:AB_2218911

      DOI: 10.7554/eLife.55771

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    ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
  67. Jan 2020
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse
    1
    1. scibot 13 Jan 2020
      RRID:AB_2218911

      DOI: 10.1016/j.ccell.2019.07.009

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    pmc.ncbi.nlm.nih.gov/articles/PMC6760242/
  69. www.sciencedirect.com www.sciencedirect.com
    A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas
    1
    1. scibot 13 Jan 2020
      RRID:AB_2218911

      DOI: 10.1016/j.devcel.2019.07.022

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    sciencedirect.com/science/article/pii/S1534580719306288
  70. www.sciencedirect.com www.sciencedirect.com
    The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes
    1
    1. scibot 13 Jan 2020
      RRID:AB_2218911

      DOI: 10.1016/j.celrep.2019.05.071

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    sciencedirect.com/science/article/pii/S2211124719307004
  71. www.sciencedirect.com www.sciencedirect.com
    Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_2218911

      DOI: 10.1016/j.stem.2019.08.007

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    sciencedirect.com/science/article/pii/S193459091930342X
  72. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.04.055

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    sciencedirect.com/science/article/pii/S2211124719305285
  73. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.devcel.2019.04.014

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    sciencedirect.com/science/article/pii/S1534580719302849
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jcp.27065

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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27065
  75. www.sciencedirect.com www.sciencedirect.com
    Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway
    1
    1. scibot 13 Jan 2020
      RRID:AB_2218911

      DOI: 10.1016/j.stem.2019.03.009

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    sciencedirect.com/science/article/pii/S1934590919301080
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.43996

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    ncbi.nlm.nih.gov/pmc/articles/PMC6461440/
  77. Nov 2018
  78. www.sciencedirect.com www.sciencedirect.com
    Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818300059
  79. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
    1
    1. scibot 05 Nov 2018
      RRID:AB_2218911

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    sciencedirect.com/science/article/pii/S1934590917304538
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5766831/
  81. academic.oup.com academic.oup.com
    Targeted Disruption of YAP and TAZ Impairs the Maintenance of the Adrenal Cortex
    1
    1. scibot 05 Nov 2018
      AB_2218911

      Curator: @evieth

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  82. Nov 2017
  83. www.sciencedirect.com www.sciencedirect.com
    Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells
    1
    1. scibot 08 Nov 2017
      4912S

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1534580717307256
  84. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
    1
    1. scibot 08 Nov 2017
      4911

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1534580717306305
  85. www.sciencedirect.com www.sciencedirect.com
    An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
    1
    1. scibot 08 Nov 2017
      AB_2218911

      Curator: @ifroman

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    sciencedirect.com/science/article/pii/S1934590917300942
  86. www.sciencedirect.com www.sciencedirect.com
    Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
    1
    1. scibot 08 Nov 2017
      AB_2218911

      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S1534580717301156
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
    1
    1. scibot 08 Nov 2017
      AB_2218911

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 4912, RRID:AB_2218911)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5360446/