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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and Their Zebrafish Homologs at the Blood-Brain Barrier
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      RRID:AB_2223172

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  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet
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    sciencedirect.com/science/article/pii/S1934590924004132
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    Proteasome inhibition induces microtubule-dependent changes in nuclear morphology
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    Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1
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    Pancreatic β cell interleukin-22 receptor subunit alpha 1 deficiency impairs β cell function in type 2 diabetes via cytochrome b5 reductase 3
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    sciencedirect.com/science/article/pii/S2211124724014086
  8. Dec 2024
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    Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration
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    Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA–induced dyskinetic behaviors
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      DOI: 10.1126/sciadv.adp6301

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    Anti-adipogenic activity of oleoresin from Nigella sativa L. seeds via modulation of PPAR-γ and C/EBP-α expression in 3T3-L1 adipocytes
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  12. 52.53.155.43 52.53.155.43
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    Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders
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  15. Nov 2024
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KS-cSCC-1 and KS-cSCC-2: two novel cutaneous squamous cell carcinoma cell lines established from Japanese patients
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    1. scibot 26 Nov 2024
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    Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms
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    Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA–induced dyskinetic behaviors
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      DOI: 10.1126/sciadv.adp6301

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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation
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    Degradome analysis to identify direct protein substrates of small-molecule degraders
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β2-integrins control HIF1α activation in human neutrophils
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  22. Oct 2024
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    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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      DOI: 10.4103/NRR.NRR-D-23-01299

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    Hypoxia-preconditioned bone marrow–derived mesenchymal stem cells protect neurons from cardiac arrest–induced pyroptosis
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      DOI: 10.4103/NRR.NRR-D-23-01922

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  25. Sep 2024
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    Pharmacologic activation of activating transcription factor 6 contributes to neuronal survival after spinal cord injury in mice
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      DOI: 10.1111/jnc.16092

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    Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing
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    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
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    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
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    Phosphorylation of Piezo1 at a single residue, serine-1612, regulates its mechanosensitivity and in vivo mechanotransduction function
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      DOI: 10.1016/j.neuron.2024.08.009

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells
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    m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
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  34. Aug 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice
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      DOI: 10.1038/s41467-024-51030-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11344041/
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    A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
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    sciencedirect.com/science/article/pii/S0092867424008328
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    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    sciencedirect.com/science/article/pii/S1535610824002708
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    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
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    Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
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      DOI: 10.1016/j.chembiol.2024.07.005

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    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
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    sciencedirect.com/science/article/pii/S2589004224017243
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    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
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      DOI: 10.1016/j.jep.2024.118650

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    sciencedirect.com/science/article/pii/S0378874124009498
  43. www.authorea.com www.authorea.com
    Preliminary exploration of endoplasmic reticulum stress transmission in astrocytes and neurons, and its mediators
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      DOI: 10.22541/au.172258066.64851176/v1

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    authorea.com/users/811586/articles/1213019-preliminary-exploration-of-endoplasmic-reticulum-stress-transmission-in-astrocytes-and-neurons-and-its-mediators
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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      DOI: 10.3389/fonc.2024.1431362

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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Frontiers | The Nonvesicular Sterol Transporter Aster-C Plays a Minor Role in Whole Body Cholesterol Balance
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    1. scibot 13 Aug 2024
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      DOI: 10.3389/fphys.2024.1371096

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy
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  48. Jul 2024
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    Impaired phase separation and nucleolar functions in hiPSC models of SNORD118-related ribosomopathies
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  62. aacrjournals.org aacrjournals.org
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    Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease
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  64. May 2024
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    Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females
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  67. 52.53.155.43 52.53.155.43
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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  130. Nov 2023
  131. www.sciencedirect.com www.sciencedirect.com
    In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells
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    Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
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  133. www.sciencedirect.com www.sciencedirect.com
    Tsc2 coordinates neuroprogenitor differentiation
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
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    Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
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    A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
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  138. 52.53.155.43 52.53.155.43
    Guanylate Binding Protein 1 (GBP1) modulates proteasomal machinery in ovarian cancer
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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    Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity
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  141. www.sciencedirect.com www.sciencedirect.com
    Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function
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    Mast-cell-specific receptor mediates alcohol-withdrawal-associated headache in male mice
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    Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice
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  144. Oct 2023
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    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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    ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modification of Lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency
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  150. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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  151. www.sciencedirect.com www.sciencedirect.com
    Comprehensive quantification of metabolic flux during acute cold stress in mice
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  152. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tyrosine hydroxylase phosphorylation is under the control of serine 40
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    Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria
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  154. Sep 2023
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for high-sensitivity western blot on murine hematopoietic stem cells
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    Generation of Novel Immunocompetent Mouse Cell Lines to Model Experimental Metastasis of High-Risk Neuroblastoma
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    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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  158. 52.53.155.43 52.53.155.43
    Different sensitivity to diet-induced hyperinsulinemia and hyperglycemia between mice with global or bone marrow-specific apoE receptor-2 deficiency
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  159. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Dai-html.html
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  160. www.sciencedirect.com www.sciencedirect.com
    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
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    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI
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  164. Aug 2023
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mitotic clonal expansion and thermogenic pathway are involved in the antiadipogenic effects of cyanidin-3-O-glucoside
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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  167. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
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    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
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  171. 52.53.155.43 52.53.155.43
    IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  174. 52.53.155.43 52.53.155.43
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine
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  177. Jul 2023
  178. www.sciencedirect.com www.sciencedirect.com
    Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
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    Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice
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    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
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    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
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    High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
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    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
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    Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response
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    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
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    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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    (A) Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis
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  206. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling
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    Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
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    LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation
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    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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