Hypothesis

31 Matching Annotations

Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Optogenetic control of biomolecular organization reveals distinct roles of phase separation in RTK signaling

1
1. scibot 04 Dec 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.chembiol.2025.11.001
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S2451945625003514
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Escitalopram attenuates spinal cord injury by suppressing NLRP3 inflammasome-mediated pyroptosis via PI3K/AKT pathway activation

1
1. scibot 04 Dec 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.bramec.2025.202525
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S3050642525000417
Nov 2025
link.springer.com link.springer.com

Network pharmacology, molecular docking, and experimental validation-based approach to explore the mechanism of action of ginsenoside Rh4 on acute myeloid leukemia cells

1
1. scibot 25 Nov 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1007/s12032-025-03128-y
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

link.springer.com/article/10.1007/s12032-025-03128-y
www.sciencedirect.com www.sciencedirect.com

C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury

1
1. scibot 22 Nov 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.neuron.2025.10.022
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627325008037
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014269-main-html.html

1
1. scibot 22 Jul 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.isci.2025.113165
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

52.53.155.43/6e3d057236c9c80ec002fca49c302ca5246dd6e8/1-s2.0-S2589004225014269-main-html.html
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer

1
1. scibot 18 Jun 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1158/0008-5472.CAN-24-3217
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12167931/
www.sciencedirect.com www.sciencedirect.com

Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer

1
1. scibot 05 Jun 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.chembiol.2025.05.004
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945625001655
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Low-intensity-pulsed-ultrasound-treated menstrual-blood-derived mesenchymal stem cells repair endometrial injury by PI3K/AKT pathway inhibition

1
1. scibot 13 Mar 2025
  
  in Public
  
  AB_2224574
  
  DOI: 10.1016/j.rbmo.2024.104486
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1472648324006758
Feb 2025
aacrjournals.org aacrjournals.org

Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition

1
1. scibot 14 Feb 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1158/1541-7786.MCR-23-0513
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

aacrjournals.org/mcr/article/22/6/538/745428/Serotonin-Receptor-HTR2B-Facilitates-Colorectal
www.sciencedirect.com www.sciencedirect.com

ERK inhibits osteoclast differentiation in RAW 264.7 cells through the osteoprotegerin-mediated autophagy

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.bone.2025.117424
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S8756328225000365
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1

1
1. scibot 23 Aug 2024
  
  in Public
  
  AB_2224574
  
  DOI: 10.1016/j.cellsig.2024.111357
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0898656824003255
www.jcancer.org www.jcancer.org

GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway

1
1. scibot 02 Aug 2024
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.7150/jca.52418
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2224574
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2224574

Annotators

scibot

URL

jcancer.org/v12p1386.htm
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of Nogo-B reduces the progression of pancreatic cancer by regulation NF-κB/GLUT1 and SREBP1 pathways

1
1. scibot 09 May 2024
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.isci.2024.109741
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11068639/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer

1
1. scibot 21 Mar 2024
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.heliyon.2024.e28172
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405844024042038
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells

1
1. scibot 03 Feb 2024
  
  in Public
  
  AB_2224574
  
  DOI: 10.1158/0008-5472.CAN-23-1632
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
Dec 2023
www.thelancet.com www.thelancet.com

Multi-omics analyses reveal bacteria and catalase associated with keloid disease

1
1. scibot 15 Dec 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.ebiom.2023.104904
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00470-X/abstract
Nov 2023
www.sciencedirect.com www.sciencedirect.com

A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.celrep.2023.113445
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014572
www.sciencedirect.com www.sciencedirect.com

Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.biopha.2023.115905
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0753332223017031
May 2023
www.nature.com www.nature.com

Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter

1
1. scibot 10 May 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1038/s41420-023-01447-5
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

nature.com/articles/s41420-023-01447-5
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway

1
1. scibot 14 Apr 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.21037/tlcr-22-675
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10087999/
Mar 2023
journals.lww.com journals.lww.com

A new peptide, VD11, promotes structural and functional... : Neural Regeneration Research

1
1. scibot 30 Mar 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.4103/1673-5374.369119
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

journals.lww.com/nrronline/Fulltext/2023/10000/A_new_peptide,_VD11,_promotes_structural_and.32.aspx
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection

1
1. scibot 26 Jan 2023
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.isci.2023.105932
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9868541/
onlinelibrary.wiley.com onlinelibrary.wiley.com

SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway

1
1. scibot 10 Jan 2023
  
  in Public
  
  RRID:10176-2-AP
  
  DOI: 10.1002/mc.23495
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRID:AB_2224574

RRIDCUR:Unresolved

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/mc.23495
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis

1
1. scibot 17 Dec 2022
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.cmet.2022.11.012
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413122005034
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer

1
1. scibot 26 Mar 2022
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.7554/eLife.68481
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8937232/
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation

1
1. scibot 16 Feb 2022
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.celrep.2022.110391
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722001127
Dec 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

SDF-1 inhibits the dedifferentiation of islet β cells in hyperglycaemia by up-regulating FoxO1 via binding to CXCR4

1
1. scibot 23 Dec 2021
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1111/jcmm.17110
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/jcmm.17110
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways

1
1. scibot 11 Dec 2021
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.3389/fcell.2021.773048
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8652204/
Oct 2021
academic.oup.com academic.oup.com

Humanin alleviates insulin resistance in polycystic ovary syndrome: a human and rat model-based study

1
1. scibot 01 Oct 2021
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1210/endocr/bqab056
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

academic.oup.com/endo/article/162/8/bqab056/6167834
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X

1
1. scibot 16 Apr 2021
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.bbr.2020.112955
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0166432820306549
Mar 2021
www.sciencedirect.com www.sciencedirect.com

An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy

1
1. scibot 01 Mar 2021
  
  in Public
  
  RRID:AB_2224574
  
  DOI: 10.1016/j.jep.2021.113806
  
  Resource: (Proteintech Cat# 10176-2-AP, RRID:AB_2224574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2224574
  
  What is this?
  
  RRID:AB_2224574
Visit annotations in context

Tags

RRID:AB_2224574

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0378874121000325