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Jul 2026
aacrjournals.org aacrjournals.org

LDHB Deficiency in Fibroblasts Induces Lactate-Mediated Inflammatory Reprogramming that Promotes Breast Cancer Metastasis

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-2792
  
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aacrjournals.org/cancerres/article/86/11/2703/785310/LDHB-Deficiency-in-Fibroblasts-Induces-Lactate
Jun 2026
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LRP1 activated by AT2 cell-secreted MDK inhibits fibrotic ferroptosis in idiopathic pulmonary fibrosis

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sciencedirect.com/science/article/pii/S2589004226015877
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

tLyP-1 peptide-modified MnO₂ co-delivering si-SLC16A1 and temozolomide synergistically suppresses glioblastoma via hypoxia modulation and metabolic stress

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  DOI: 10.1186/s12951-026-04256-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13200357/
Apr 2026
54.241.53.176 54.241.53.176

lin-et-al-2026-exercise-ameliorates-adipose-tissue-insulin-resistance-by-activating-the-lactate-gpr81-signaling-pathway-html.html

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54.241.53.176/a809efb51b41ea4d9d4ec968d70be26daee9aa88/lin-et-al-2026-exercise-ameliorates-adipose-tissue-insulin-resistance-by-activating-the-lactate-gpr81-signaling-pathway-html.html
54.241.53.176 54.241.53.176

1-s2.0-S2589004226011594-main-html.html

2
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54.241.53.176/f5256e21ee20a00f69c63c4703de1421dc5aa480/1-s2.0-S2589004226011594-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nerves Stimulate Cross-talk Between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression

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pmc.ncbi.nlm.nih.gov/articles/PMC13080324/
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Dendrobine alleviates the T2D/AD comorbidity in 3xTg-AD mice feeding high-fat diet via the Cav-1/PERK/CHOP pathways

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sciencedirect.com/science/article/pii/S0014299926003298
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CBX2 phase-separation contributes to homologous recombination repair and drug resistance in ovarian cancer

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  DOI: 10.1038/s41419-026-08605-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13039389/
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mycobacterial metallophosphatase MmpE acts as a nucleomodulin to regulate host gene expression and promote intracellular survival

1
1. scibot 21 Mar 2026
  
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  DOI: 10.7554/eLife.108037
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12999176/
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Streptococcus anginosus-generated succinate promotes the progression of gastric cancer via the succinate/SUCNR1/ABRAXAS1 axis

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  DOI: 10.1016/j.celrep.2026.117047
  
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sciencedirect.com/science/article/pii/S2211124726001257
Jan 2026
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Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion

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  DOI: 10.1016/j.cmet.2025.11.014
  
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sciencedirect.com/science/article/pii/S1550413125005285
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Macrophage glycine transporter supports IL-1β production by modulating the AKT1/mTOR/NLRP3 pathway

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  DOI: 10.1016/j.celrep.2025.116683
  
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sciencedirect.com/science/article/pii/S221112472501455X
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Optogenetic control of biomolecular organization reveals distinct roles of phase separation in RTK signaling

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.chembiol.2025.11.001
  
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sciencedirect.com:5037/science/article/pii/S2451945625003514
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Escitalopram attenuates spinal cord injury by suppressing NLRP3 inflammasome-mediated pyroptosis via PI3K/AKT pathway activation

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.bramec.2025.202525
  
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sciencedirect.com:5037/science/article/pii/S3050642525000417
Nov 2025
link.springer.com link.springer.com

Network pharmacology, molecular docking, and experimental validation-based approach to explore the mechanism of action of ginsenoside Rh4 on acute myeloid leukemia cells

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1. scibot 25 Nov 2025
  
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  DOI: 10.1007/s12032-025-03128-y
  
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link.springer.com/article/10.1007/s12032-025-03128-y
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C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury

1
1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.neuron.2025.10.022
  
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sciencedirect.com/science/article/pii/S0896627325008037
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014269-main-html.html

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113165
  
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52.53.155.43/6e3d057236c9c80ec002fca49c302ca5246dd6e8/1-s2.0-S2589004225014269-main-html.html
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer

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1. scibot 18 Jun 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12167931/
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Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer

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sciencedirect.com/science/article/pii/S2451945625001655
Mar 2025
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Low-intensity-pulsed-ultrasound-treated menstrual-blood-derived mesenchymal stem cells repair endometrial injury by PI3K/AKT pathway inhibition

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  DOI: 10.1016/j.rbmo.2024.104486
  
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sciencedirect.com/science/article/pii/S1472648324006758
Feb 2025
aacrjournals.org aacrjournals.org

Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition

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1. scibot 14 Feb 2025
  
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  DOI: 10.1158/1541-7786.MCR-23-0513
  
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aacrjournals.org/mcr/article/22/6/538/745428/Serotonin-Receptor-HTR2B-Facilitates-Colorectal
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ERK inhibits osteoclast differentiation in RAW 264.7 cells through the osteoprotegerin-mediated autophagy

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.bone.2025.117424
  
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sciencedirect.com/science/article/pii/S8756328225000365
Aug 2024
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Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1

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sciencedirect.com/science/article/pii/S0898656824003255
www.jcancer.org www.jcancer.org

GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway

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  DOI: 10.7150/jca.52418
  
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jcancer.org/v12p1386.htm
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of Nogo-B reduces the progression of pancreatic cancer by regulation NF-κB/GLUT1 and SREBP1 pathways

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  DOI: 10.1016/j.isci.2024.109741
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11068639/
Mar 2024
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MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer

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  DOI: 10.1016/j.heliyon.2024.e28172
  
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sciencedirect.com/science/article/pii/S2405844024042038
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells

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  DOI: 10.1158/0008-5472.CAN-23-1632
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
Dec 2023
www.thelancet.com www.thelancet.com

Multi-omics analyses reveal bacteria and catalase associated with keloid disease

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  DOI: 10.1016/j.ebiom.2023.104904
  
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thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00470-X/abstract
Nov 2023
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A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder

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  DOI: 10.1016/j.celrep.2023.113445
  
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sciencedirect.com/science/article/pii/S2211124723014572
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Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

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  DOI: 10.1016/j.biopha.2023.115905
  
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sciencedirect.com/science/article/pii/S0753332223017031
May 2023
www.nature.com www.nature.com

Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter

1
1. scibot 10 May 2023
  
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  DOI: 10.1038/s41420-023-01447-5
  
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nature.com/articles/s41420-023-01447-5
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway

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1. scibot 14 Apr 2023
  
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  RRID:AB_2224574
  
  DOI: 10.21037/tlcr-22-675
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10087999/
Mar 2023
journals.lww.com journals.lww.com

A new peptide, VD11, promotes structural and functional... : Neural Regeneration Research

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1. scibot 30 Mar 2023
  
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  RRID:AB_2224574
  
  DOI: 10.4103/1673-5374.369119
  
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journals.lww.com/nrronline/Fulltext/2023/10000/A_new_peptide,_VD11,_promotes_structural_and.32.aspx
Jan 2023
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Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection

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1. scibot 26 Jan 2023
  
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  DOI: 10.1016/j.isci.2023.105932
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9868541/
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SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway

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1. scibot 10 Jan 2023
  
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  RRID:10176-2-AP
  
  DOI: 10.1002/mc.23495
  
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onlinelibrary.wiley.com/doi/10.1002/mc.23495
Dec 2022
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Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis

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  DOI: 10.1016/j.cmet.2022.11.012
  
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sciencedirect.com/science/article/pii/S1550413122005034
Mar 2022
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Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer

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1. scibot 26 Mar 2022
  
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  DOI: 10.7554/eLife.68481
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8937232/
Feb 2022
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Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation

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  DOI: 10.1016/j.celrep.2022.110391
  
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sciencedirect.com/science/article/pii/S2211124722001127
Dec 2021
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SDF-1 inhibits the dedifferentiation of islet β cells in hyperglycaemia by up-regulating FoxO1 via binding to CXCR4

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1. scibot 23 Dec 2021
  
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  DOI: 10.1111/jcmm.17110
  
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onlinelibrary.wiley.com/doi/10.1111/jcmm.17110
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Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways

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  DOI: 10.3389/fcell.2021.773048
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8652204/
Oct 2021
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Humanin alleviates insulin resistance in polycystic ovary syndrome: a human and rat model-based study

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  DOI: 10.1210/endocr/bqab056
  
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academic.oup.com/endo/article/162/8/bqab056/6167834
Apr 2021
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Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X

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  DOI: 10.1016/j.bbr.2020.112955
  
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Mar 2021
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An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy

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  DOI: 10.1016/j.jep.2021.113806
  
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sciencedirect.com/science/article/pii/S0378874121000325