Hypothesis

109 Matching Annotations

Feb 2026
54.241.53.176 54.241.53.176

2026.01.31.703051.full-html.html

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1. scibot 12 Feb 2026
  
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  AB_2232946
  
  DOI: 10.64898/2026.01.31.703051
  
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54.241.53.176/817d1ae27212347f382894a7416c0a21d3d8e9f2/2026.01.31.703051.full-html.html
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus

1
1. scibot 22 Jan 2026
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.celrep.2025.116600
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12812013/
Nov 2025
54.241.53.176 54.241.53.176

ouahmi-et-al-2025-the-eif5a-hypusination-inhibitor-gc7-improves-tolerance-of-pancreatic-beta-cells-to-ischemia-html.html

1
1. scibot 25 Nov 2025
  
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  AB_2232946
  
  DOI: 10.6084/m9.figshare.30234790
  
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54.241.53.176/74637dc2e8be2bbf1ae8549b1f995d9ea967ffd3/ouahmi-et-al-2025-the-eif5a-hypusination-inhibitor-gc7-improves-tolerance-of-pancreatic-beta-cells-to-ischemia-html.html
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis

1
1. scibot 14 Aug 2025
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.devcel.2025.07.014
  
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sciencedirect.com/science/article/pii/S153458072500471X
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

1
1. scibot 16 Jul 2025
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.cell.2025.06.027
  
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sciencedirect.com/science/article/pii/S0092867425007287
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PRPS activity tunes redox homeostasis in Myc-driven lymphoma

1
1. scibot 18 Jun 2025
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.redox.2025.103649
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
May 2025
www.sciencedirect.com www.sciencedirect.com

Lymphatic endothelial mTORC1 instructs metabolic and developmental signaling during lymphangiogenesis

1
1. scibot 17 May 2025
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.devcel.2025.04.012
  
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sciencedirect.com/science/article/pii/S1534580725002503
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Protein O-GlcNAcylation and hexokinase mitochondrial dissociation drive heart failure with preserved ejection fraction

1
1. scibot 24 Apr 2025
  
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  AB_2232946
  
  DOI: 10.1016/j.cmet.2025.04.001
  
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sciencedirect.com/science/article/pii/S1550413125002116
Mar 2025
www.biorxiv.org www.biorxiv.org

Neuropilin 2 stabilises adherens junctions and protects against endothelial activation by promoting the interaction between VE cadherin and p120 catenin

1
1. scibot 14 Mar 2025
  
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  AB_2232946
  
  DOI: 10.1101/2025.03.09.642194
  
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biorxiv.org/content/10.1101/2025.03.09.642194v1
Feb 2025
aacrjournals.org aacrjournals.org

Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment

1
1. scibot 14 Feb 2025
  
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  RRID:AB_2232946
  
  DOI: 10.1158/2159-8290.CD-21-1022
  
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aacrjournals.org/cancerdiscovery/article/12/7/1718/705192/IFN-Potentiates-Anti-PD-1-Efficacy-by-Remodeling
Nov 2024
www.sciencedirect.com www.sciencedirect.com

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.cmet.2024.10.015
  
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sciencedirect.com/science/article/pii/S155041312400411X
Sep 2024
dx.doi.org dx.doi.org

Mild Cold Stress at Ambient Temperature Elevates Muscle Calcium Cycling and Exercise Adaptations in Obese Female Mice

1
1. scibot 27 Sep 2024
  
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  AB_2232946
  
  DOI: 10.1210/endocr/bqae102
  
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dx.doi.org/10.1210/endocr/bqae102
Aug 2024
www.sciencedirect.com www.sciencedirect.com

CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

1
1. scibot 21 Aug 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.cmet.2017.10.006
  
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sciencedirect.com/science/article/pii/S1550413117306186
www.cell.com www.cell.com

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway

1
1. scibot 02 Aug 2024
  
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  HK2
  
  DOI: 10.1016/j.molcel.2020.11.008
  
  Resource: (Cell Signaling Technology Cat# 2867, RRID:AB_2232946)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:AB_2232946
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cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
www.sciencedirect.com www.sciencedirect.com

Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition

1
1. scibot 02 Aug 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.celrep.2021.109202
  
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sciencedirect.com/science/article/pii/S2211124721005519
Apr 2024
52.53.155.43 52.53.155.43

JNEUROSCI.1563-23.2024.full (1)-html.html

1
1. scibot 26 Apr 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1523/jneurosci.1563-23.2024
  
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52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
www.embopress.org www.embopress.org

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

2
1. scibot 23 Apr 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1038/s44318-024-00065-w
  
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  RRID:AB_2232946
2. scibot 23 Apr 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1038/s44318-024-00065-w
  
  Resource: (Cell Signaling Technology Cat# 2867, RRID:AB_2232946)
  
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embopress.org/doi/10.1038/s44318-024-00065-w
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa

1
1. scibot 23 Apr 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.xcrm.2024.101459
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11031380/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

1
1. scibot 19 Apr 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1038/s44318-024-00065-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

1
1. scibot 29 Mar 2024
  
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  AB_2232946
  
  DOI: 10.1016/j.bbadis.2024.167131
  
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sciencedirect.com/science/article/pii/S0925443924001200
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PRMT1 promotes pancreatic cancer development and resistance to chemotherapy

2
1. scibot 12 Mar 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.xcrm.2024.101461
  
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2. scibot 12 Mar 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.xcrm.2024.101461
  
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sciencedirect.com/science/article/pii/S2666379124001058
Feb 2024
52.53.155.43 52.53.155.43

A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

2
1. scibot 29 Feb 2024
  
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  AB_2232946
  
  DOI: 10.1101/2023.10.24.563545
  
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2. scibot 29 Feb 2024
  
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  AB_2232946
  
  DOI: 10.1101/2023.10.24.563545
  
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52.53.155.43/208912a7429960b4182882fc2fcf60d73a185bc4/delete-html.html
www.sciencedirect.com www.sciencedirect.com

Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer

1
1. scibot 16 Feb 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.molmet.2024.101900
  
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sciencedirect.com/science/article/pii/S2212877824000310
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Augmentation of scleral glycolysis promotes myopia through histone lactylation

1
1. scibot 19 Jan 2024
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.cmet.2023.12.023
  
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sciencedirect.com/science/article/pii/S1550413123004746
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.celrep.2023.113424
  
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sciencedirect.com/science/article/pii/S2211124723014365
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Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration

2
1. scibot 22 Nov 2023
  
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  RRID: AB_2232946
  
  DOI: 10.1016/j.cmet.2023.10.017
  
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  Curator: @olekpark
  
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2. scibot 22 Nov 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.cmet.2023.10.017
  
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sciencedirect.com/science/article/pii/S1550413123003868
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS

1
1. scibot 04 Nov 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.isci.2023.108168
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
Oct 2023
www.sciencedirect.com www.sciencedirect.com

MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer

1
1. scibot 13 Oct 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.celrep.2023.113221
  
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sciencedirect.com/science/article/pii/S2211124723012330
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine

1
1. scibot 12 Oct 2023
  
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  RRID:AB_2232946
  
  DOI: 10.3892/ol.2023.14067
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10561147/
Sep 2023
www.nature.com www.nature.com

Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate

1
1. scibot 22 Sep 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1038/s41422-023-00874-4
  
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nature.com/articles/s41422-023-00874-4
dx.doi.org dx.doi.org

Insulin Signaling Is Preserved in Skeletal Muscle During Early Diabetic Ketoacidosis

1
1. scibot 14 Sep 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1210/clinem/dgad464
  
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dx.doi.org/10.1210/clinem/dgad464
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis

1
1. scibot 22 Jul 2023
  
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  RRID:AB_2232946
  
  DOI: 10.1016/j.cmet.2023.06.013
  
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sciencedirect.com/science/article/pii/S1550413123002231
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Acetate controls endothelial-to-mesenchymal transition

1
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Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity

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IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins

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Experimental evidence and clinical implications of Warburg effect in the skeletal muscle of Fabry disease

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NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer

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Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis

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Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation

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Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3

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Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions

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A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice

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Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection

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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

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DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism

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Hexokinase 1 cellular localization regulates the metabolic fate of glucose

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Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch

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GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure

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Differences in Glycolysis and Mitochondrial Respiration between Cytotrophoblast and Syncytiotrophoblast In-Vitro: Evidence for Sexual Dimorphism

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PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes

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Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE

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Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells

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Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS

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LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

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Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

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Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK

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CRISPR screens in physiologic medium reveal conditionally essential genes in human cells

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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

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Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer

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Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS

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Cardiac expression and location of hexokinase changes in a mouse model of pure creatine-deficiency

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Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

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Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses

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Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency | American Journal of Physiology-Heart and Circulatory Physiology

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Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab

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Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation

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An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors

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ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism

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Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity

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Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis

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Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules

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Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer

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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

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Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity

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Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

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HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

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Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab

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BPS Publications

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Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

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Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring

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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

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Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS

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Hepatic HKDC1 Expression Contributes to Liver Metabolism

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Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation

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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

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Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

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Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth

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Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism

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Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

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Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

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Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species

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Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients

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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma

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Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

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Hexokinase 2‐dependent Hyperglycolysis Driving Microglial Activation Contributes to Ischemic Brain Injury

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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses

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RRID:AB_2232946

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S1550413117304977
elifesciences.org elifesciences.org

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2232946
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2867, RRID:AB_2232946)
  
  SciCrunch record: RRID:AB_2232946
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2232946 RRIDCUR:Validated
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RRID:AB_2232946

RRIDCUR:Validated

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scibot

URL

elifesciences.org/articles/25217
www.sciencedirect.com www.sciencedirect.com

Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2232946
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2867, RRID:AB_2232946)
  
  SciCrunch record: RRID:AB_2232946
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2232946 RRIDCUR:Validated
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RRID:AB_2232946

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S109727651730360X

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