99 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion
    1
    1. scibot 24 Nov 2024
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2024.10.015

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    sciencedirect.com/science/article/pii/S155041312400411X
  3. Sep 2024
  4. dx.doi.org dx.doi.org
    Mild Cold Stress at Ambient Temperature Elevates Muscle Calcium Cycling and Exercise Adaptations in Obese Female Mice
    1
    1. scibot 27 Sep 2024
      AB_2232946

      DOI: 10.1210/endocr/bqae102

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    dx.doi.org/10.1210/endocr/bqae102
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
    1
    1. scibot 21 Aug 2024
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2017.10.006

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    sciencedirect.com/science/article/pii/S1550413117306186
  7. www.cell.com www.cell.com
    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
    1
    1. scibot 02 Aug 2024
      HK2

      DOI: 10.1016/j.molcel.2020.11.008

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  8. www.sciencedirect.com www.sciencedirect.com
    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition
    1
    1. scibot 02 Aug 2024
      RRID:AB_2232946

      DOI: 10.1016/j.celrep.2021.109202

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    sciencedirect.com/science/article/pii/S2211124721005519
  9. Apr 2024
  10. 52.53.155.43 52.53.155.43
    JNEUROSCI.1563-23.2024.full (1)-html.html
    1
    1. scibot 26 Apr 2024
      RRID:AB_2232946

      DOI: 10.1523/jneurosci.1563-23.2024

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    52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
  11. www.embopress.org www.embopress.org
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
    2
    1. scibot 23 Apr 2024
      RRID:AB_2232946

      DOI: 10.1038/s44318-024-00065-w

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      DOI: 10.1038/s44318-024-00065-w

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    embopress.org/doi/10.1038/s44318-024-00065-w
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa
    1
    1. scibot 23 Apr 2024
      RRID:AB_2232946

      DOI: 10.1016/j.xcrm.2024.101459

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    ncbi.nlm.nih.gov/pmc/articles/PMC11031380/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
    1
    1. scibot 19 Apr 2024
      RRID:AB_2232946

      DOI: 10.1038/s44318-024-00065-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
  14. Mar 2024
  15. www.sciencedirect.com www.sciencedirect.com
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
    1
    1. scibot 29 Mar 2024
      AB_2232946

      DOI: 10.1016/j.bbadis.2024.167131

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    sciencedirect.com/science/article/pii/S0925443924001200
  16. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy
    2
    1. scibot 12 Mar 2024
      RRID:AB_2232946

      DOI: 10.1016/j.xcrm.2024.101461

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      RRID:AB_2232946

      DOI: 10.1016/j.xcrm.2024.101461

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    sciencedirect.com/science/article/pii/S2666379124001058
  17. Feb 2024
  18. 52.53.155.43 52.53.155.43
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
    2
    1. scibot 29 Feb 2024
      AB_2232946

      DOI: 10.1101/2023.10.24.563545

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      AB_2232946

      DOI: 10.1101/2023.10.24.563545

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    52.53.155.43/208912a7429960b4182882fc2fcf60d73a185bc4/delete-html.html
  19. www.sciencedirect.com www.sciencedirect.com
    Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer
    1
    1. scibot 16 Feb 2024
      RRID:AB_2232946

      DOI: 10.1016/j.molmet.2024.101900

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    sciencedirect.com/science/article/pii/S2212877824000310
  20. Jan 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Augmentation of scleral glycolysis promotes myopia through histone lactylation
    1
    1. scibot 19 Jan 2024
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2023.12.023

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    sciencedirect.com/science/article/pii/S1550413123004746
  22. Nov 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell
    1
    1. scibot 28 Nov 2023
      RRID:AB_2232946

      DOI: 10.1016/j.celrep.2023.113424

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    sciencedirect.com/science/article/pii/S2211124723014365
  24. www.sciencedirect.com www.sciencedirect.com
    Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
    2
    1. scibot 22 Nov 2023
      RRID: AB_2232946

      DOI: 10.1016/j.cmet.2023.10.017

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    2. scibot 22 Nov 2023
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2023.10.017

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    sciencedirect.com/science/article/pii/S1550413123003868
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS
    1
    1. scibot 04 Nov 2023
      RRID:AB_2232946

      DOI: 10.1016/j.isci.2023.108168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
  26. Oct 2023
  27. www.sciencedirect.com www.sciencedirect.com
    MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
    1
    1. scibot 13 Oct 2023
      RRID:AB_2232946

      DOI: 10.1016/j.celrep.2023.113221

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    sciencedirect.com/science/article/pii/S2211124723012330
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
    1
    1. scibot 12 Oct 2023
      RRID:AB_2232946

      DOI: 10.3892/ol.2023.14067

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561147/
  29. Sep 2023
  30. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
    1
    1. scibot 22 Sep 2023
      RRID:AB_2232946

      DOI: 10.1038/s41422-023-00874-4

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    nature.com/articles/s41422-023-00874-4
  31. dx.doi.org dx.doi.org
    Insulin Signaling Is Preserved in Skeletal Muscle During Early Diabetic Ketoacidosis
    1
    1. scibot 14 Sep 2023
      RRID:AB_2232946

      DOI: 10.1210/clinem/dgad464

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    dx.doi.org/10.1210/clinem/dgad464
  32. Jul 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
    1
    1. scibot 22 Jul 2023
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2023.06.013

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    sciencedirect.com/science/article/pii/S1550413123002231
  34. Jun 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Acetate controls endothelial-to-mesenchymal transition
    1
    1. scibot 21 Jun 2023
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2023.05.010

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    sciencedirect.com/science/article/pii/S1550413123002036
  36. May 2023
  37. link.springer.com link.springer.com
    Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity
    1
    1. scibot 18 May 2023
      RRID:AB_2232946

      DOI: 10.1038/s41598-023-33924-3

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    link.springer.com/article/10.1038/s41598-023-33924-3
  38. Mar 2023
  39. www.ijbs.com www.ijbs.com
    IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins
    1
    1. scibot 30 Mar 2023
      RRID:AB_2232946

      DOI: 10.7150/ijbs.78248

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    ijbs.com/v19p1490.htm
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Experimental evidence and clinical implications of Warburg effect in the skeletal muscle of Fabry disease
    1
    1. scibot 09 Mar 2023
      RRID:AB_2232946

      DOI: 10.1016/j.isci.2023.106074

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    ncbi.nlm.nih.gov/pmc/articles/PMC9984560/
  41. Feb 2023
  42. www.sciencedirect.com www.sciencedirect.com
    NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
    1
    1. scibot 25 Feb 2023
      RRID:AB_2232946

      DOI: 10.1016/j.cmet.2023.01.012

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    sciencedirect.com/science/article/pii/S1550413123000128
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
    1
    1. scibot 15 Feb 2023
      RRID:AB_2232946

      DOI: 10.7554/eLife.86471

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910825/
  44. www.sciencedirect.com www.sciencedirect.com
    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
    1
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      DOI: 10.1016/j.celrep.2023.112033

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    sciencedirect.com/science/article/pii/S221112472300044X
  45. Jan 2023
  46. www.nature.com www.nature.com
    Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3
    1
    1. scibot 28 Jan 2023
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      DOI: 10.1038/s41598-023-28576-2

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    nature.com/articles/s41598-023-28576-2
  47. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions
    1
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      RRID:AB_2232946

      DOI: 10.1016/j.isci.2022.105811

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    sciencedirect.com/science/article/pii/S2589004222020843
  48. Nov 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
    1
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      DOI: 10.1158/2767-9764.crc-22-0256

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648418/
  50. Jun 2022
  51. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
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    1. scibot 30 Jun 2022
      RRID:AB_2232946

      DOI: 10.1158/2159-8290.CD-21-1022

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      DOI: 10.1158/2159-8290.cd-21-1022

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      DOI: 10.1158/2159-8290.cd-21-1022

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    52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
  52. www.sciencedirect.com www.sciencedirect.com
    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.isci.2022.104447

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    sciencedirect.com/science/article/pii/S2589004222007180
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
    1
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      RRID:AB_2232946

      DOI: 10.3389/fphar.2022.848957

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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
  54. May 2022
  55. www.sciencedirect.com www.sciencedirect.com
    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
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      RRID:AB_2232946

      DOI: 10.1016/j.devcel.2022.04.020

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  56. Apr 2022
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  62. Oct 2021
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    Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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      DOI: 10.1016/j.celrep.2019.07.097

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    Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers
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      DOI: 10.1016/j.celrep.2019.07.063

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    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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  114. academic.oup.com academic.oup.com
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      DOI: 10.1210/en.2018-00887

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    Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism
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      DOI: 10.1016/j.ebiom.2018.12.019

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  116. Nov 2018
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species
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    Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients
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    The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
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    Transcriptional Regulation of the Warburg Effect in Cancer by SIX1
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    Hexokinase 2‐dependent Hyperglycolysis Driving Microglial Activation Contributes to Ischemic Brain Injury
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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  126. Nov 2017
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    Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses
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  128. elifesciences.org elifesciences.org
    HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium
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    Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake
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