37 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
    1
    1. scibot 10 Dec 2024
      RRID:AB_2234877

      DOI: 10.1016/j.cell.2024.11.009

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    sciencedirect.com/science/article/pii/S0092867424013266
  3. Sep 2024
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impaired cellular copper regulation in the presence of ApoE4
    1
    1. scibot 27 Sep 2024
      RRID:AB_2234877

      DOI: 10.1111/jnc.16198

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16198
  5. Aug 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
    1
    1. scibot 21 Aug 2024
      RRID:AB_2234877

      DOI: 10.4103/NRR.NRR-D-23-01525

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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
  7. Jul 2024
  8. www.sciencedirect.com www.sciencedirect.com
    PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms
    1
    1. scibot 25 Jul 2024
      AB_2234877

      DOI: 10.1016/j.celrep.2024.114527

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    sciencedirect.com/science/article/pii/S2211124724008568
  9. www.sciencedirect.com www.sciencedirect.com
    Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
    1
    1. scibot 24 Jul 2024
      AB_2234877

      DOI: 10.1016/j.cmet.2024.05.016

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    sciencedirect.com/science/article/pii/S155041312400192X
  10. May 2024
  11. www.mdpi.com www.mdpi.com
    Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function
    1
    1. scibot 21 May 2024
      RRID:AB_2234877

      DOI: 10.3390/ijms25105417

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    mdpi.com/1422-0067/25/10/5417
  12. Dec 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
    1
    1. scibot 28 Dec 2023
      RRID:AB_2234877

      DOI: 10.1158/0008-5472.CAN-23-1252

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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  14. Aug 2023
  15. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
    1
    1. scibot 11 Aug 2023
      RRID:AB_2234877

      DOI: 10.1158/0008-5472.CAN-23-1252

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    52.53.155.43/ea1e2390c2d37ea00d2075acaef6f5d93e41dc17/can-23-1252-html.html
  16. Jul 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
    1
    1. scibot 22 Jul 2023
      RRID:AB_2234877

      DOI: 10.1016/j.xcrm.2023.101129

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    sciencedirect.com/science/article/pii/S2666379123002574
  18. Jun 2023
  19. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 01 Jun 2023
      RRID:AB_2234877

      DOI: 10.1111/bph.16065

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16065
  20. May 2023
  21. www.mdpi.com www.mdpi.com
    Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function
    1
    1. scibot 06 May 2023
      AB_2234877

      DOI: 10.3390/cells10020413

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    mdpi.com/2073-4409/10/2/413/htm
  22. Dec 2022
  23. link.springer.com link.springer.com
    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
    1
    1. scibot 29 Dec 2022
      RRID:AB_2234877

      DOI: 10.1007/s12035-022-03153-2

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    link.springer.com/article/10.1007/s12035-022-03153-2
  24. May 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Cholesterol determines the cytosolic entry and seeded aggregation of tau
    1
    1. scibot 13 May 2022
      RRID:AB_2234877

      DOI: 10.1016/j.celrep.2022.110776

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    sciencedirect.com/science/article/pii/S221112472200540X
  26. Apr 2022
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibiting α1-adrenergic receptor signaling pathway ameliorates AD-type pathologies and behavioral deficits in APPswe/PS1 mouse model
    1
    1. scibot 05 Apr 2022
      RRID:AB_2234877

      DOI: 10.1111/jnc.15603

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15603
  28. Mar 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat
    1
    1. scibot 30 Mar 2022
      RRID:AB_2234877

      DOI: 10.1016/j.celrep.2022.110566

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    sciencedirect.com/science/article/pii/S2211124722003102
  30. www.sciencedirect.com www.sciencedirect.com
    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
    1
    1. scibot 02 Mar 2022
      RRID:AB_2234877

      DOI: 10.1016/j.celrep.2022.110423

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    sciencedirect.com/science/article/pii/S2211124722001474
  31. Jan 2022
  32. www.embopress.org www.embopress.org
    Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance
    1
    1. scibot 22 Jan 2022
      RRID:AB_2234877

      DOI: 10.15252/embr.202153373

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    embopress.org/doi/full/10.15252/embr.202153373
  33. Nov 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
    1
    1. scibot 19 Nov 2021
      RRID:AB_2234877

      DOI: 10.1016/j.neuron.2021.10.036

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    sciencedirect.com/science/article/pii/S0896627321008667
  35. Oct 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
    1
    1. scibot 09 Oct 2021
      RRID:AB_2234877

      DOI: 10.1016/j.devcel.2021.09.015

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    sciencedirect.com/science/article/pii/S1534580721007334
  37. Aug 2021
  38. www.nature.com www.nature.com
    Untitled document
    1
    1. scibot 04 Aug 2021
      RRID:AB_2234877

      DOI: 10.1038/s41598-019-39494-7

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    nature.com/articles/s41598-019-39494-7
  39. Jul 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer’s Disease Mouse Model
    1
    1. scibot 28 Jul 2021
      RRID:AB_2234877

      DOI: 10.3389/fnagi.2018.00186

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      Curator: @evieth

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      RRID:AB_2234877 RRIDCUR:Unrecognized
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    ncbi.nlm.nih.gov/pmc/articles/PMC6028735/
  41. Apr 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
    1
    1. scibot 30 Apr 2021
      RRID:AB_2234877

      DOI: 10.1016/j.cmet.2020.10.020

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    sciencedirect.com/science/article/pii/S1550413120305532
  43. Feb 2021
  44. link.springer.com link.springer.com
    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
    1
    1. scibot 25 Feb 2021
      RRID:AB_2234877

      DOI: 10.1186/s13024-020-00366-8

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    link.springer.com/article/10.1186/s13024-020-00366-8
  45. Jan 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse
    1
    1. scibot 30 Jan 2021
      RRID:AB_2234877

      DOI: 10.3389/fncel.2020.567253

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    ncbi.nlm.nih.gov/pmc/articles/PMC7842215/
  47. Dec 2020
  48. www.sciencedirect.com www.sciencedirect.com
    Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy
    1
    1. scibot 22 Dec 2020
      RRID:AB_2234877

      DOI: 10.1016/j.ebiom.2020.103156

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    sciencedirect.com/science/article/pii/S2352396420305326
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Is a Negative Regulator of Oligodendrocyte Progenitor Cell Differentiation in the Adult Mouse Brain
    1
    1. scibot 09 Dec 2020
      RRID:AB_2234877

      DOI: 10.3389/fcell.2020.564351

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    ncbi.nlm.nih.gov/pmc/articles/PMC7691426/
  50. Oct 2020
  51. www.sciencedirect.com www.sciencedirect.com
    PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer
    1
    1. scibot 21 Oct 2020
      AB_2234877

      DOI: 10.1016/j.celrep.2020.108253

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    sciencedirect.com/science/article/pii/S2211124720312420
  52. Sep 2020
  53. link.springer.com link.springer.com
    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
    1
    1. scibot 26 Sep 2020
      RRID:AB_2234877

      DOI: 10.1186/s13024-020-00366-8

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    link.springer.com/article/10.1186/s13024-020-00366-8
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures
    1
    1. scibot 08 Sep 2020
      RRID:AB_2234877

      DOI: 10.1002/glia.23869

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    onlinelibrary.wiley.com/doi/10.1002/glia.23869
  55. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
    1
    1. scibot 04 Sep 2020
      LRP1

      DOI: 10.1096/fj.202000678R

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      Curator comments: LRP1 antibody [EPR3724] Abcam Cat# ab92544

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      RRIDCUR:Missing RRID:AB_2234877
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202000678R
  56. Jan 2020
  57. jcb.rupress.org jcb.rupress.org
    A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor
    1
    1. scibot 13 Jan 2020
      RRID:AB_2234877

      DOI: 10.1083/jcb.201806205

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    jcb.rupress.org/content/218/2/644
  58. jem.rupress.org jem.rupress.org
    Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2234877

      DOI: 10.1084/jem.20181102

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    jem.rupress.org/content/216/2/350
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight
    1
    1. scibot 13 Jan 2020
      RRID:AB_2234877

      DOI: 10.1038/s41598-019-39494-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC6391466/
  60. Nov 2018
  61. www.sciencedirect.com www.sciencedirect.com
    Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression
    1
    1. scibot 05 Nov 2018
      RRID:AB_2234877

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    sciencedirect.com/science/article/pii/S0896627318306834
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair
    1
    1. scibot 05 Nov 2018
      RRID:AB_2234877

      Curator: @evieth

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      (Abcam Cat# ab92544, RRID:AB_2234877)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5752207/
  63. europepmc.org europepmc.org
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_2234877

      Curator: @evieth

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      RRID:AB_2234877 RRIDCUR:Validated
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    europepmc.org/articles/PMC5752207/
  64. Nov 2017
  65. www.sciencedirect.com www.sciencedirect.com
    Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers
    1
    1. scibot 08 Nov 2017
      AB_2234877

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    sciencedirect.com/science/article/pii/S1934590916302661