184 Matching Annotations
  1. Last 7 days
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    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    1. scibot 10 May 2024
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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  3. May 2024
  4. 52.53.155.43 52.53.155.43
    Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy
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      DOI: 10.1093/braincomms/fcae136

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  5. Apr 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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      DOI: 10.1016/j.stem.2024.03.013

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    sciencedirect.com/science/article/pii/S1934590924000948
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    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
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    sciencedirect.com/science/article/pii/S0092867424003064
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    KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
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      DOI: 10.1016/j.stem.2024.03.004

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    sciencedirect.com/science/article/pii/S1934590924000857
  9. Mar 2024
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    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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      DOI: 10.1016/j.neuron.2024.02.017

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      DOI: 10.1016/j.neuron.2024.02.017

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    sciencedirect.com/science/article/pii/S0896627324001272
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
  12. Feb 2024
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    Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer’s disease profile and possible mechanisms of disease protection
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    sciencedirect.com/science/article/pii/S089662732400093X
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    Large-scale visualisation of α-synuclein oligomers in Parkinson’s disease brain tissue
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      DOI: 10.1101/2024.02.17.580698

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    biorxiv.org/content/10.1101/2024.02.17.580698v1
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease
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      RRID:AB_223647

      DOI: 10.1093/brain/awad388

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    ncbi.nlm.nih.gov/pmc/articles/PMC10834249/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioural, metabolic and lipidomic characterisation of the 5xFADxTg30 mouse model of Alzheimer’s Disease.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10826307/
  17. Jan 2024
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glioblastoma and its treatment are associated with extensive accelerated brain aging
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      DOI: 10.1111/acel.14066

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    onlinelibrary.wiley.com/doi/10.1111/acel.14066
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Protocol for screening α-synuclein PET tracer candidates in vitro and ex vivo
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    sciencedirect.com/science/article/pii/S2666166723007554
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10731794/
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    Early Alzheimer’s disease pathology in human cortex involves transient cell states
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    sciencedirect.com/science/article/pii/S0092867423008590
  23. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients
    1
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      DOI: 10.1002/alz.13557

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    alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.13557
  24. Nov 2023
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    Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease
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      DOI: 10.1016/j.celrep.2023.113436

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    sciencedirect.com/science/article/pii/S2211124723014481
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    APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
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      DOI: 10.1016/j.celrep.2023.113252

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    sciencedirect.com/science/article/pii/S2211124723012640
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    The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy
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      DOI: 10.1016/j.celrep.2023.113342

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    sciencedirect.com/science/article/pii/S2211124723013542
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
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      DOI: 10.1016/j.celrep.2023.113310

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    sciencedirect.com/science/article/pii/S2211124723013220
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
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      DOI: 10.3389/fnagi.2023.1265151

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    ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
  31. www.biorxiv.org www.biorxiv.org
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread
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      DOI: 10.1101/2023.10.06.561190

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    biorxiv.org/content/10.1101/2023.10.06.561190v1
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determinants of astrocytic pathology in stem cell models of primary tauopathies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10557325/
  33. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    A Human Neuron/Astrocyte Co-culture to Model Seeded and Spontaneous Intraneuronal Tau Aggregation
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      DOI: 10.1002/cpz1.900

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.900
  34. www.cell.com www.cell.com
    Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease
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      DOI: 10.1016/j.celrep.2023.113071

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    cell.com/cell-reports/abstract/S2211-1247(23)01082-3
  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Early Alzheimer’s disease pathology in human cortex involves transient cell states
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      DOI: 10.1016/j.cell.2023.08.005

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    sciencedirect.com/science/article/pii/S0092867423008590
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Assessing individual variability of the entorhinal subfields in health and disease
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      DOI: 10.1002/cne.25538

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    onlinelibrary.wiley.com/doi/10.1002/cne.25538
  38. Aug 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1550413123002735
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    Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1
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      DOI: 10.1016/j.celrep.2023.112994

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    sciencedirect.com/science/article/pii/S2211124723010057
  41. 52.53.155.43 52.53.155.43
    s41596-023-00861-4-html.html
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      DOI: 10.1038/s41593-018-0175-4

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    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
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      DOI: 10.1016/j.celrep.2023.112889

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    sciencedirect.com/science/article/pii/S2211124723009002
  43. Jul 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies
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      DOI: 10.1016/j.cell.2023.06.004

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    sciencedirect.com/science/article/abs/pii/S009286742300644X
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    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
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      DOI: 10.1016/j.neuron.2023.06.002

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    sciencedirect.com/science/article/pii/S0896627323004373
  46. www.sciencedirect.com www.sciencedirect.com
    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
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      DOI: 10.1016/j.celrep.2023.112725

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    sciencedirect.com/science/article/pii/S2211124723007362
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation
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      DOI: 10.1016/j.neuron.2023.05.033

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    sciencedirect.com/science/article/pii/S0896627323004348
  49. www.biorxiv.org www.biorxiv.org
    KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
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      DOI: 10.1101/2023.06.12.543777

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    biorxiv.org/content/10.1101/2023.06.12.543777v1
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    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
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      DOI: 10.1016/j.neuron.2023.05.006

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    sciencedirect.com/science/article/pii/S0896627323003793
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex specific molecular networks and key drivers of Alzheimer’s disease
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      DOI: 10.1186/s13024-023-00624-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10280841/
  52. www.sciencedirect.com www.sciencedirect.com
    Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity
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      DOI: 10.1016/j.isci.2023.106905

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    sciencedirect.com/science/article/pii/S2589004223009823
  53. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  54. May 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain
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      DOI: 10.1016/j.neuron.2023.04.020

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  56. Apr 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
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      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  58. Mar 2023
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of phosphorylated Tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission.
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    Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model
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      DOI: 10.3390/biomedicines11041004

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    Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model
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      DOI: 10.1016/j.isci.2023.106342

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    Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy
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  63. journals.sagepub.com journals.sagepub.com
    Thioflavin S Staining and Amyloid Formation Are Unique to Mixed Tauopathies
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      DOI: 10.1369/00221554231158428

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  64. Feb 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Cofilin promotes tau pathology in Alzheimer’s disease
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      DOI: 10.1016/j.celrep.2023.112138

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    Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer’s disease
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      DOI: 10.1016/j.isci.2023.106152

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  67. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
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      DOI: 10.1038/s41467-023-36058-2

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  68. Jan 2023
  69. www.sciencedirect.com www.sciencedirect.com
    Neuronal vulnerability to brain aging and neurodegeneration in cognitively impaired marmoset monkeys (Callithrix jacchus)
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    Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration
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  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain
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      DOI: 10.1002/jnr.25167

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  72. 52.53.155.43 52.53.155.43
    Intraneuronal tau aggregation induces the integrated stress response in astrocytes
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      DOI: 10.1093/jmcb/mjac071

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  73. Dec 2022
  74. link.springer.com link.springer.com
    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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      DOI: 10.1007/s12035-022-03153-2

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  75. link.springer.com link.springer.com
    Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
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  76. Nov 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Spread of pathological human Tau from neurons to oligodendrocytes and loss of high-firing pyramidal neurons in aging mice
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  78. Oct 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altered low-frequency brain rhythms precede changes in gamma power during tauopathy
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  80. www.sciencedirect.com www.sciencedirect.com
    SYK coordinates neuroprotective microglial responses in neurodegenerative disease
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      DOI: 10.1016/j.cell.2022.09.030

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    Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis
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      DOI: 10.1016/j.medj.2022.09.007

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  82. Sep 2022
  83. www.sciencedirect.com www.sciencedirect.com
    Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer’s models
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    A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency
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      DOI: 10.1016/j.xcrm.2022.100740

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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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      DOI: 10.1016/j.crmeth.2022.100289

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  86. Aug 2022
  87. www.sciencedirect.com www.sciencedirect.com
    Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration
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    Effects of cereblon on stress-activated redox proteins and core behavior
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRP1 Inflammasome Activation in the Hippocampal Formation in Alzheimer’s Disease: Correlation with Neuropathological Changes and Unbiasedly Estimated Neuronal Loss
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      DOI: 10.3390/cells11142223

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  90. Jul 2022
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      DOI: 10.21203/rs.3.rs-1791270/v1

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    Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease
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    Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease
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  94. Jun 2022
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    Evidence of traumatic brain injury in headbutting bovids
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    Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
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    Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
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  99. May 2022
  100. www.sciencedirect.com www.sciencedirect.com
    Cholesterol determines the cytosolic entry and seeded aggregation of tau
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    Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment
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    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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  103. Apr 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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  105. Mar 2022
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees
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      DOI: 10.1002/cne.24610

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  107. www.embopress.org www.embopress.org
    Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission
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  108. www.sciencedirect.com www.sciencedirect.com
    Familial natural short sleep mutations reduce Alzheimer pathology in mice
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  109. link.springer.com link.springer.com
    Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
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  110. www.sciencedirect.com www.sciencedirect.com
    Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crry silencing alleviates Alzheimer’s disease injury by regulating neuroinflammatory cytokines and the complement system
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  112. Feb 2022
  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau nuclear translocation is a leading step in tau pathology process through P53 stabilization and nucleolar dispersion
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  114. Jan 2022
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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    Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model
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  117. Dec 2021
  118. www.frontiersin.org www.frontiersin.org
    Layer-Specific Vesicular Glutamate Transporter 1 Immunofluorescence Levels Delineate All Layers of the Human Hippocampus Including the Stratum lucidum
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  119. Nov 2021
  120. www.sciencedirect.com www.sciencedirect.com
    The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function
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  121. Oct 2021
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer’s disease in nonhuman primates
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  123. Sep 2021
  124. www.sciencedirect.com www.sciencedirect.com
    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
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    IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease
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    Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau
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  128. Aug 2021
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    ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
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  130. www.frontiersin.org www.frontiersin.org
    In vivo Bioluminescence Imaging Used to Monitor Disease Activity and Therapeutic Response in a Mouse Model of Tauopathy
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      DOI: 10.3389/fnagi.2019.00252

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  131. amrcopenresearch.org amrcopenresearch.org
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  132. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1523/JNEUROSCI.1230-17.2017

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  134. www.sciencedirect.com www.sciencedirect.com
    Secretion of Tau via an Unconventional Non-vesicular Mechanism
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  136. www.jneurosci.org www.jneurosci.org
    GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
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  137. www.sciencedirect.com www.sciencedirect.com
    Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer’s Disease
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  138. Jul 2021
  139. academic.oup.com academic.oup.com
    Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment
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      tau phosphorylated on S202 and T205

      DOI: 10.1093/hmg/ddz255

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  141. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Saccadic Palsy following Cardiac Surgery: Possible Role of Perineuronal Nets
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  143. www.sciencedirect.com www.sciencedirect.com
    Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
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      DOI: 10.1016/j.neuron.2018.10.014

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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  145. www.jneurosci.org www.jneurosci.org
    A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
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  146. www.sciencedirect.com www.sciencedirect.com
    Secretion of Tau via an Unconventional Non-vesicular Mechanism
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  147. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1523/JNEUROSCI.1353-14.2014

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  149. www.jneurosci.org www.jneurosci.org
    GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
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      DOI: 10.1523/JNEUROSCI.2393-17.2017

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  150. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment
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      DOI: 10.1002/cne.23877

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  151. www.sciencedirect.com www.sciencedirect.com
    Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature
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      DOI: 10.1186/s40478-021-01220-8

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  153. Jun 2021
  154. www.jneurosci.org www.jneurosci.org
    Cereblon regulates the proteotoxicity of tau by tuning the chaperone activity of DNAJA1
    1
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      RRID:AB_223647

      DOI: 10.1523/JNEUROSCI.2494-20.2021

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  155. www.sciencedirect.com www.sciencedirect.com
    Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice
    1
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      MN1020

      DOI: 10.1016/j.neurobiolaging.2021.06.012

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    sciencedirect.com/science/article/pii/S0197458021002062
  156. May 2021
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction
    1
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      RRID:AB_223647

      DOI: 10.7554/eLife.65301

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    ncbi.nlm.nih.gov/pmc/articles/PMC8139826/
  158. www.sciencedirect.com www.sciencedirect.com
    Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
    1
    1. scibot 08 May 2021
      RRID:AB_223647

      DOI: 10.1016/j.neuron.2021.02.010

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    sciencedirect.com/science/article/pii/S0896627321000842
  159. www.sciencedirect.com www.sciencedirect.com
    Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
    1
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      DOI: 10.1016/j.neuron.2020.11.002

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    sciencedirect.com/science/article/pii/S0896627320308618
  160. www.sciencedirect.com www.sciencedirect.com
    Impaired Hippocampal-Cortical Interactions during Sleep in a Mouse Model of Alzheimer’s Disease
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      RRID:AB_223647

      DOI: 10.1016/j.cub.2020.04.087

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    sciencedirect.com/science/article/pii/S0960982220306357
  161. Apr 2021
  162. www.sciencedirect.com www.sciencedirect.com
    Tau seeds are subject to aberrant modifications resulting in distinct signatures
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      RRID:AB_223647

      DOI: 10.1016/j.celrep.2021.109037

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    sciencedirect.com/science/article/pii/S2211124721003533
  163. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia
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      RRID:AB_223647

      DOI: 10.1016/j.cell.2020.07.011

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  164. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
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      DOI: 10.1016/j.cell.2021.03.048

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    sciencedirect.com/science/article/pii/S0092867421003792
  165. www.sciencedirect.com www.sciencedirect.com
    Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components
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      RRID:AB_223647

      DOI: 10.1016/j.neuron.2021.03.026

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    sciencedirect.com/science/article/pii/S0896627321001963
  166. Mar 2021
  167. onlinelibrary.wiley.com onlinelibrary.wiley.com
    α‐Synuclein Abnormalities Trigger Focal Tau Pathology, Spreading to Various Brain Areas in Parkinson’s Disease
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      DOI: 10.1111/jnc.15257

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15257
  168. Feb 2021
  169. www.nature.com www.nature.com
    MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis
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      RRID:AB_223647

      DOI: 10.1038/s41380-020-0824-3

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    nature.com/articles/s41380-020-0824-3
  170. www.nature.com www.nature.com
    Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway
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      DOI: 10.1038/s41538-021-00084-5

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  171. Jan 2021
  172. link.springer.com link.springer.com
    GSK-3β Disrupts Neuronal Oscillatory Function to Inhibit Learning and Memory in Male Rats
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    1. scibot 06 Jan 2021
      mouse anti-phospho tau (AT8)

      DOI: 10.1007/s10571-020-01020-z

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  173. Nov 2020
  174. www.sciencedirect.com www.sciencedirect.com
    High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies
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      RRID:AB_223647

      DOI: 10.1016/j.neuron.2020.09.042

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  175. Oct 2020
  176. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression
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      RRID:AB_223647

      DOI: 10.1111/jnc.15189

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15189
  177. link.springer.com link.springer.com
    Plasma Leptin Reflects Progression of Neurofibrillary Pathology in Animal Model of Tauopathy
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      RRID:AB_223647

      DOI: 10.1007/s10571-020-00972-6

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  178. Sep 2020
  179. www.sciencedirect.com www.sciencedirect.com
    Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission
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      RRID:AB_223647

      DOI: 10.1016/j.stem.2019.12.015

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    sciencedirect.com/science/article/pii/S1934590919305739
  180. www.jneurosci.org www.jneurosci.org
    Activated CX3CL1/Smad2 signals prevent neuronal loss and Alzheimer's tau pathology-mediated cognitive dysfunction
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      RRID:AB_223647

      DOI: 10.1523/JNEUROSCI.1333-19.2019

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    jneurosci.org/content/40/5/1133
  181. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Correcting abnormalities in miR‐124/PTPN1 signaling rescues tau pathology in Alzheimer’s disease
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      AB_223647

      DOI: 10.1111/jnc.14961

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14961
  182. www.sciencedirect.com www.sciencedirect.com
    Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease
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      RRID:AB_223647

      DOI: 10.1016/j.cmet.2020.02.004

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    sciencedirect.com/science/article/pii/S1550413120300632
  183. elifesciences.org elifesciences.org
    Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau
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      RRID:AB_223647

      DOI: 10.7554/eLife.51859

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    elifesciences.org/articles/51859
  184. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Aggrecan modulates the expression and phosphorylation of tau in a novel bigenic TauP301L ‐ acan mouse model
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      RRID:AB_223647

      DOI: 10.1111/ejn.14923

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    onlinelibrary.wiley.com/doi/10.1111/ejn.14923
  185. insight.jci.org insight.jci.org
    Identification of Alzheimer’s disease–associated rare coding variants in the <i>ECE2</i> gene
    1
    1. scibot 04 Sep 2020
      tau

      DOI: 10.1172/jci.insight.135119

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  186. Jan 2020
  187. link.springer.com link.springer.com
    Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease
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      RRID:AB_223647

      DOI: 10.1186/s40478-019-0836-x

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      DOI: 10.1186/s40478-019-0836-x

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  188. www.sciencedirect.com www.sciencedirect.com
    Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
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      RRID:AB_223647

      DOI: 10.1016/j.celrep.2019.07.060

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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia changes associated to Alzheimer’s disease pathology in aged chimpanzees
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      RRID:AB_223647

      DOI: 10.1002/cne.24484

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    ncbi.nlm.nih.gov/pmc/articles/PMC6283685/
  190. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay
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      RRID:AB_223647

      DOI: 10.1111/jnc.14830

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  191. www.sciencedirect.com www.sciencedirect.com
    Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease
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      RRID:AB_223647

      DOI: 10.1016/j.celrep.2019.06.054

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    sciencedirect.com/science/article/pii/S2211124719308277
  192. www.sciencedirect.com www.sciencedirect.com
    The neuritic plaque in Alzheimer's disease: Perivascular degeneration of neuronal processes
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      RRID:AB_223647

      DOI: 10.1016/j.neurobiolaging.2019.06.009

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  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    β‐amyloid and Tau Pathology in the Aging Feline Brain
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      RRID:AB_223647

      DOI: 10.1002/cne.24741

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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24741
  194. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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      RRID:AB_223647

      DOI: 10.3389/fncel.2019.00399

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    frontiersin.org/article/10.3389/fncel.2019.00399/full
  195. www.jneurosci.org www.jneurosci.org
    Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin
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      RRID:AB_223647

      DOI: 10.1523/JNEUROSCI.3632-16.2017

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    jneurosci.org/content/37/12/3181
  196. www.sciencedirect.com www.sciencedirect.com
    The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice
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      RRID:AB_223647

      DOI: 10.1016/j.mcn.2019.103409

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    sciencedirect.com/science/article/pii/S1044743119300661
  197. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_223647

      DOI: 10.1016/j.celrep.2018.12.085

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  198. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.nbd.2018.12.009

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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_223647

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  200. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/cne.24610

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  201. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.01.023

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  202. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies
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      RRID:AB_223647

      DOI: 10.1111/jnc.14647

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14647
  203. Nov 2018
  204. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody
    1
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      RRID:AB_223647

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0969212618303265
  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_223647

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    ncbi.nlm.nih.gov/pmc/articles/PMC6154927/
  206. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-018-0603-4
  207. www.sciencedirect.com www.sciencedirect.com
    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
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    sciencedirect.com/science/article/pii/S0896627318303805
  208. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      Curator: @anp055

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24447
  209. www.sciencedirect.com www.sciencedirect.com
    Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease
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    sciencedirect.com/science/article/pii/S0197458017304062
  210. www.sciencedirect.com www.sciencedirect.com
    Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
    1
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      ThermoFisher Scientific#MN1020

      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S2213231717306687
  211. Nov 2017
  212. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fluorine‐19 magnetic resonance imaging probe for the detection of tau pathology in female rTg4510 mice
    1
    1. scibot 08 Nov 2017
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      Curator: @patriciaelyse_

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24188/full
  213. www.nature.com www.nature.com
    ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury
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    nature.com/articles/s41598-017-11654-7
  214. www.sciencedirect.com www.sciencedirect.com
    Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer’s Disease
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517305361
  215. www.sciencedirect.com www.sciencedirect.com
    Local Somatodendritic Translation and Hyperphosphorylation of Tau Protein Triggered by AMPA and NMDA Receptor Stimulation
    1
    1. scibot 08 Nov 2017
      AB_223647

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S2352396417302098
  216. www.sciencedirect.com www.sciencedirect.com
    Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
    1
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      AB_223647

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0896627317300582
  217. www.sciencedirect.com www.sciencedirect.com
    Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease
    1
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      AB_223647

      Curator: @Zeljana_Babic

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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Saccadic Palsy following Cardiac Surgery: Possible Role of Perineuronal Nets
    2
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      AB_223647

      Curator: @jcabotaj

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      AB_223647

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    ncbi.nlm.nih.gov/pmc/articles/PMC4489868/
  219. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Physiologically relevant factors influence tau phosphorylation by leucine‐rich repeat kinase 2
    1
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      AB_223647

      Curator: @gabimpine

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23614/full
  220. www.jneurosci.org www.jneurosci.org
    Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates
    1
    1. scibot 08 Nov 2017
      AB_223647

      Curator: @gabimpine

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    jneurosci.org/content/34/41/13629.long
  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway
    1
    1. scibot 08 Nov 2017
      AB_223647

      Curator: @jcabotaj

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    ncbi.nlm.nih.gov/pmc/articles/PMC4160782/