25 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recapitulation of plaque formation, tau pathology, and neurodegeneration in a human 3D matrix model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13106978/
  3. www.biorxiv.org www.biorxiv.org
    Discovery and Preclinical Validation of a Clinically Optimized Mitochondrial Complex I Modulator for Alzheimer’s Disease
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    biorxiv.org/content/10.64898/2026.04.10.717554v1
  4. Apr 2026
  5. www.biorxiv.org www.biorxiv.org
    Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer’s disease iPSC-derived cortical organoids
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    biorxiv.org/content/10.1101/2025.06.25.661453v2
  6. Mar 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alzheimer’s disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits
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    pmc.ncbi.nlm.nih.gov/articles/PMC13045655/
  8. Dec 2025
  9. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology
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    sciencedirect.com:5037/science/article/pii/S2666379125005932
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PP2A methylesterase, PME‐1, and PP2A methyltransferase, LCMT‐1, control sensitivity to impairments caused by injury‐related oligomeric tau
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    pmc.ncbi.nlm.nih.gov/articles/PMC12701366/
  11. Sep 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Biomarker-related phospho-tau217 appears in synapses around Aβ plaques prior to tau tangle in cerebral cortex of preclinical Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S221112472500974X
  13. May 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12069431/
  15. Jan 2025
  16. dx.doi.org dx.doi.org
    Intramural hematomas and astrocytic infiltration precede perivascular inflammation in a rat model of repetitive low-level blast injury
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    dx.doi.org/10.1093/jnen/nlaf003
  17. Apr 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
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    sciencedirect.com/science/article/pii/S0092867424003064
  19. Oct 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
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    sciencedirect.com/science/article/pii/S2211124723013220
  21. Aug 2023
  22. www.sciencedirect.com www.sciencedirect.com
    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
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    sciencedirect.com/science/article/pii/S2211124723009002
  23. Jun 2023
  24. www.biorxiv.org www.biorxiv.org
    KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
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    biorxiv.org/content/10.1101/2023.06.12.543777v1
  25. Aug 2022
  26. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Phosphorylated tau sites that are elevated in Alzheimer's disease fluid biomarkers are visualized in early neurofibrillary tangle maturity levels in the post mortem brain
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    alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12749
  27. May 2022
  28. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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    link.springer.com/article/10.1186/s13024-022-00526-y
  29. Mar 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Familial natural short sleep mutations reduce Alzheimer pathology in mice
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    sciencedirect.com/science/article/pii/S2589004222002346
  31. Sep 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
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    sciencedirect.com/science/article/pii/S089662732100578X
  33. Aug 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
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    sciencedirect.com/science/article/pii/S1097276521006225
  35. Jul 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
  37. Oct 2020
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15189
  39. link.springer.com link.springer.com
    Plasma Leptin Reflects Progression of Neurofibrillary Pathology in Animal Model of Tauopathy
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    link.springer.com/article/10.1007/s10571-020-00972-6
  40. Sep 2020
  41. www.jneurosci.org www.jneurosci.org
    AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation
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    jneurosci.org/content/40/25/4798
  42. Jan 2020
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14830
  44. Nov 2018
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
  46. Nov 2017
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Physiologically relevant factors influence tau phosphorylation by leucine‐rich repeat kinase 2
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23614/full