Hypothesis

92 Matching Annotations

Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225021376-main-html.html

1
1. scibot 29 Oct 2025
  
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  AB_2239535
  
  DOI: 10.1016/j.isci.2025.113876
  
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54.241.53.176/1317e59fd2d0f056081cc0eecb18d40452c42a91/1-s2.0-S2589004225021376-main-html.html
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma

1
1. scibot 31 Jul 2025
  
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  RRID: AB_2239535
  
  DOI: 10.1186/s12943-025-02408-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12306140/
www.nature.com www.nature.com

Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis

1
1. scibot 08 Jul 2025
  
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  AB_2239535
  
  DOI: 10.1038/s42003-025-08440-x
  
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nature.com/articles/s42003-025-08440-x
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells

1
1. scibot 18 Jun 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1152/ajplung.00400.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12169631/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR/Cas9 Screening Highlights PFKFB3 Gene as a Major Contributor to 5-Fluorouracil Resistance in Esophageal Cancer

1
1. scibot 12 Jun 2025
  
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  RRID:AB_2239535
  
  DOI: 10.3390/cancers17101637
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12109790/
May 2025
www.sciencedirect.com www.sciencedirect.com

Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity

1
1. scibot 31 May 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.chom.2025.05.004
  
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sciencedirect.com/science/article/pii/S1931312825001830
Apr 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma

1
1. scibot 17 Apr 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1002/mc.23913
  
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onlinelibrary.wiley.com/doi/full/10.1002/mc.23913
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HAND1, partially mediated through ape-specific LTR binding, is essential for human extra-embryonic mesenchyme derivation from iPSCs

1
1. scibot 15 Apr 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2025.115568
  
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sciencedirect.com/science/article/pii/S2211124725003390
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 10 Apr 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1158/1541-7786.mcr-24-0957
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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52.53.155.43/009f5d6e39c430064ce0b832cf798a7e9caafb80/PDF-html.html
Feb 2025
aacrjournals.org aacrjournals.org

LRRC75A-AS1 drives the epithelial-mesenchymal transition in cervical cancer by binding IGF2BP1 and inhibiting SYVN1-mediated NLRP3 ubiquitination

1
1. scibot 14 Feb 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1158/1541-7786.MCR-23-0478
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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aacrjournals.org/mcr/article/22/12/1075/750095/LRRC75A-AS1-Drives-the-Epithelial-Mesenchymal
aacrjournals.org aacrjournals.org

TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

1
1. scibot 13 Feb 2025
  
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  AB_2239535
  
  DOI: 10.1158/0008-5472.CAN-22-3009
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
Jan 2025
www.sciencedirect.com www.sciencedirect.com

ERBB4 selectively amplifies TGF-β pro-metastatic responses

1
1. scibot 24 Jan 2025
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2024.115210
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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sciencedirect.com/science/article/pii/S2211124724015614
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

1
1. scibot 13 Dec 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1038/s44321-024-00161-8
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

1
1. scibot 24 Jul 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2021.109363
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
May 2024
52.53.155.43 52.53.155.43

mcr-23-0478-html.html

2
1. scibot 23 May 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1158/1541-7786.mcr-23-0478
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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  RRID:AB_2239535
2. scibot 23 May 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1158/1541-7786.mcr-23-0478
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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52.53.155.43/a4d1b1195ce648b46cbdc2b7d1e41b22ba16f57e/mcr-23-0478-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Janus kinase 1 is critical for pancreatic cancer initiation and progression

1
1. scibot 14 May 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2024.114202
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
Apr 2024
52.53.155.43 52.53.155.43

mcr-23-0478-html.html

1
1. scibot 19 Apr 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1158/1541-7786.mcr-23-0478
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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52.53.155.43/a4d1b1195ce648b46cbdc2b7d1e41b22ba16f57e/mcr-23-0478-html.html
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice

2
1. scibot 06 Mar 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2024.113875
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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  RRID:AB_2239535
2. scibot 06 Mar 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2024.113875
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124724002031
Feb 2024
www.sciencedirect.com www.sciencedirect.com

The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

1
1. scibot 08 Feb 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk

1
1. scibot 11 Jan 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.stem.2023.12.002
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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sciencedirect.com/science/article/pii/S1934590923004320
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma

1
1. scibot 05 Jan 2024
  
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  RRID:AB_2239535
  
  DOI: 10.1080/10985549.2023.2256640
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10761179/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas

1
1. scibot 20 Dec 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1186/s40478-023-01677-9
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10725030/
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Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion

1
1. scibot 19 Dec 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2023.113586
  
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sciencedirect.com/science/article/pii/S221112472301598X
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells

1
1. scibot 27 Oct 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.xgen.2023.100424
  
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sciencedirect.com/science/article/pii/S2666979X23002501
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Fusobacterium nucleatum promotes colorectal cancer metastasis by excretion of miR-122-5p from cells via exosomes

1
1. scibot 07 Sep 2023
  
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  RRID: AB_2239535
  
  DOI: 10.1016/j.isci.2023.107686
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @olekpark
  
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sciencedirect.com/science/article/pii/S2589004223017637
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SHOX2 promotes prostate cancer proliferation and metastasis through disruption of the Hippo-YAP pathway

1
1. scibot 02 Sep 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.isci.2023.107617
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10470409/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

1
1. scibot 01 Aug 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1101/2023.07.14.549074
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10370032/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1

1
1. scibot 27 Jul 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.isci.2023.107346
  
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sciencedirect.com/science/article/pii/S2589004223014232
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Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia

1
1. scibot 21 Jul 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2023.112804
  
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sciencedirect.com/science/article/pii/S221112472300815X
Jun 2023
www.sciencedirect.com www.sciencedirect.com

SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

1
1. scibot 23 Jun 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.isci.2023.106994
  
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sciencedirect.com/science/article/pii/S2589004223010714
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Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation

1
1. scibot 22 Jun 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2023.112646
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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sciencedirect.com/science/article/pii/S2211124723006575
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ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression

1
1. scibot 21 Jun 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1016/j.celrep.2023.112654
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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sciencedirect.com/science/article/pii/S2211124723006654
aacrjournals.org aacrjournals.org

USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis

1
1. scibot 10 Jun 2023
  
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  RRID:AB_2239535
  
  DOI: 10.1158/1541-7786.MCR-22-0552
  
  Resource: (Cell Signaling Technology Cat# 9585, RRID:AB_2239535)
  
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aacrjournals.org/mcr/article/21/6/578/726510/USP10-Regulates-ZEB1-Ubiquitination-and-Protein
link.springer.com link.springer.com

KDM4B down-regulation facilitated breast cancer cell stemness via PHGDH upregulation in H3K36me3-dependent manner

1
1. scibot 01 Jun 2023
  
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Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

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Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture

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Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells

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Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis

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hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease

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Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

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ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis

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MYO10-filopodia support basement membranes at pre-invasive tumor boundaries

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Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways

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Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling

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Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines

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Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis

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EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer

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Completion of neural crest cell production and emigration is regulated by retinoic-acid-dependent inhibition of BMP signaling

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Human spinal cord in vitro differentiation pace is initially maintained in heterologous embryonic environments

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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

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Glutamine-dependent signaling controls pluripotent stem cell fate

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Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion

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Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway

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Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1

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Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency

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Dual role for CXCL12 signaling in semilunar valve development

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The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

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Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

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Untitled document

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Genomic Function of Estrogen Receptor Beta In Endometriosis

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KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

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Essential function and targets of BMP signaling during midbrain neural crest delamination

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Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells

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Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer

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Alisertib inhibits migration and invasion of EGFR-TKI resistant cells by partially reversing the epithelial-mesenchymal transition

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Isorhamnetin Inhibits Human Gallbladder Cancer Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway Inactivation

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  DOI: 10.3389/fphar.2021.628621
  
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Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis

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  DOI: 10.1038/s41596-020-00412-1
  
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Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

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Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

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Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics

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PRMT1-p53 Pathway Controls Epicardial EMT and Invasion

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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Human axial progenitors generate trunk neural crest cells in vitro

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  DOI: 10.7554/eLife.35786
  
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Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

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Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics

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Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway

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H1N1 Influenza Virus Cross-Activates Gli1 to Disrupt the Intercellular Junctions of Alveolar Epithelial Cells

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currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Establishing Primary Cultures of Trunk Neural Crest Cells

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Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

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Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

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  DOI: 10.1016/j.ebiom.2019.08.074
  
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LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors

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  DOI: 10.1016/j.celrep.2019.07.058
  
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Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma

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Nov 2018
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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

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Untitled document

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academic.oup.com/endo/article/159/4/1644/4861804

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