39 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
    1
    1. scibot 12 Sep 2024
      AB_2256326

      DOI: 10.1016/j.cell.2024.08.020

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    sciencedirect.com/science/article/pii/S0092867424009115
  3. Aug 2024
  4. www.embopress.org www.embopress.org
    DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging
    1
    1. scibot 02 Aug 2024
      sc-22760

      DOI: 10.15252/embr.202153658

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    embopress.org/doi/full/10.15252/embr.202153658
  5. Apr 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
    1
    1. scibot 02 Apr 2024
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2024.114006

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    ncbi.nlm.nih.gov/pmc/articles/PMC11272184/
  7. Jan 2024
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    BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
    1
    1. scibot 25 Jan 2024
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2023.12.040

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    sciencedirect.com/science/article/pii/S1097276523010869
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    Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair
    1
    1. scibot 09 Jan 2024
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2023.113656

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    sciencedirect.com/science/article/pii/S2211124723016674
  10. Dec 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
    1
    1. scibot 19 Dec 2023
      RRID:AB_2256326

      DOI: 10.1016/j.chembiol.2023.11.008

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    sciencedirect.com/science/article/pii/S2451945623004233
  12. Jul 2023
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
    1
    1. scibot 21 Jul 2023
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2023.06.025

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    sciencedirect.com/science/article/pii/S1097276523004720
  14. 52.53.155.43 52.53.155.43
    GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
    1
    1. scibot 18 Jul 2023
      RRID:AB_2256326

      DOI: 10.15252/embr.202256437

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    52.53.155.43/82562d81b2014f2e2d5c134f5e9ab42cec01f29a/embr.202256437-html.html
  15. Apr 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
    1
    1. scibot 20 Apr 2023
      RRID:AB_2256326

      DOI: 10.1126/sciadv.ade7997

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    ncbi.nlm.nih.gov/pmc/articles/PMC10104471/
  17. www.science.org www.science.org
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
    1
    1. scibot 20 Apr 2023
      RRID:AB_2256326

      DOI: 10.1126/sciadv.ade7997

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    science.org/doi/10.1126/sciadv.ade7997
  18. Mar 2023
  19. www.sciencedirect.com www.sciencedirect.com
    HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression
    1
    1. scibot 23 Mar 2023
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2023.112284

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    sciencedirect.com/science/article/pii/S2211124723002954
  20. Aug 2022
  21. www.sciencedirect.com www.sciencedirect.com
    RAD51 protects human cells from transcription-replication conflicts
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    1. scibot 26 Aug 2022
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2022.07.010

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    sciencedirect.com/science/article/pii/S1097276522007067
  22. Apr 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
    1
    1. scibot 08 Apr 2022
      RRID:AB_2256326

      DOI: 10.1016/j.isci.2022.104142

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    sciencedirect.com/science/article/pii/S2589004222004126
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    MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells
    1
    1. scibot 06 Apr 2022
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2022.110602

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    sciencedirect.com/science/article/pii/S2211124722003503
  25. Mar 2022
  26. www.embopress.org www.embopress.org
    K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
    1
    1. scibot 31 Mar 2022
      RRID:AB_2256326

      DOI: 10.15252/embj.2021110145

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    embopress.org/doi/abs/10.15252/embj.2021110145
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    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
    1
    1. scibot 04 Mar 2022
      RRID:AB_2256326

      DOI: 10.1016/j.devcel.2022.02.013

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    sciencedirect.com/science/article/pii/S153458072200079X
  28. Dec 2021
  29. www.sciencedirect.com www.sciencedirect.com
    Assessing kinetics and recruitment of DNA repair factors using high content screens
    1
    1. scibot 29 Dec 2021
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2021.110176

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    sciencedirect.com/science/article/pii/S2211124721016764
  30. www.sciencedirect.com www.sciencedirect.com
    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
    1
    1. scibot 09 Dec 2021
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2021.110080

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    sciencedirect.com/science/article/pii/S2211124721015710
  31. Aug 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 11 Aug 2021
      AB_2256326

      DOI: 10.7554/eLife.23872

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    ncbi.nlm.nih.gov/pmc/articles/PMC5426901/
  33. Feb 2021
  34. www.sciencedirect.com www.sciencedirect.com
    AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ
    1
    1. scibot 24 Feb 2021
      Rabbit polyclonal anti-53BP1

      DOI: 10.1016/j.celrep.2021.108713

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    sciencedirect.com/science/article/pii/S2211124721000267
  35. Jan 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
    1
    1. scibot 27 Jan 2021
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2020.108680

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    sciencedirect.com/science/article/pii/S2211124720316697
  37. Nov 2020
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress
    1
    1. scibot 21 Nov 2020
      RRID:AB_2256326

      DOI: 10.7554/eLife.58020

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    ncbi.nlm.nih.gov/pmc/articles/PMC7671687/
  39. Sep 2020
  40. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency
    1
    1. scibot 14 Sep 2020
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2020.107985

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    sciencedirect.com/science/article/pii/S2211124720309700
  41. Jan 2020
  42. www.sciencedirect.com www.sciencedirect.com
    The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function
    1
    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2019.11.012

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    sciencedirect.com/science/article/pii/S2211124719314834
  43. www.sciencedirect.com www.sciencedirect.com
    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
    1
    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2019.06.043

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    sciencedirect.com/science/article/pii/S1097276519305003
  44. www.sciencedirect.com www.sciencedirect.com
    Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.cell.2019.06.002

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    sciencedirect.com/science/article/pii/S0092867419306300
  45. www.sciencedirect.com www.sciencedirect.com
    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
    1
    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2019.10.026

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    sciencedirect.com/science/article/pii/S1097276519308044
  46. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
    1
    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.15252/embj.2019102361

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    embopress.org/doi/10.15252/embj.2019102361
  47. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2018.11.036

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    sciencedirect.com/science/article/pii/S1097276518310062
  48. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2019.02.014

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    sciencedirect.com/science/article/pii/S1097276519301042
  49. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.celrep.2019.02.008

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    sciencedirect.com/science/article/pii/S2211124719301706
  50. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2256326

      DOI: 10.1016/j.molcel.2019.04.024

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    sciencedirect.com/science/article/pii/S1097276519303168
  51. Nov 2018
  52. www.sciencedirect.com www.sciencedirect.com
    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
    1
    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518307858
  53. www.sciencedirect.com www.sciencedirect.com
    Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
    1
    1. scibot 05 Nov 2018
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1097276518301424
  54. Nov 2017
  55. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
    1
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      RRID:AB_2256326

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    sciencedirect.com/science/article/pii/S1097276517306184
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    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610817303549
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    Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2405471217303319
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    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
    1
    1. scibot 08 Nov 2017
      AB_2256326

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1097276517303192
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    NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres
    1
    1. scibot 08 Nov 2017
      AB_2256326

      Curator: @Zeljana_Babic

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      RRID:AB_2256326 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517300424