95 Matching Annotations
  1. Feb 2026
  2. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226003718-main-html.html
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    54.241.53.176/f373af50e20ad2f683c3912e0dfb19a86e14ace7/1-s2.0-S2589004226003718-main-html.html
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11792891/
  4. www.sciencedirect.com www.sciencedirect.com
    Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction
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    sciencedirect.com/science/article/pii/S1934590926000251
  5. Jan 2026
  6. www.nature.com www.nature.com
    PDZRN4 suppresses lung adenocarcinoma progression via inhibiting ubiquitin-mediated HIF-1A degradation
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    nature.com/articles/s41388-025-03670-z
  7. Dec 2025
  8. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Hepatic adaptation to chronic metabolic stress primes tumorigenesis
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    sciencedirect.com:5037/science/article/pii/S0092867425013662
  9. Oct 2025
  10. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    sciencedirect.com/science/article/pii/S2211124725012586
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485380/
  12. Jul 2025
  13. www.science.org www.science.org
    An in vivo screen identifies NAT10 as a master regulator of brain metastasis
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    science.org/doi/10.1126/sciadv.ads6021
  14. 52.53.155.43 52.53.155.43
    Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html
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    52.53.155.43/baf73dc4816d69ae4de3fa32641dfd7bd010d8a5/Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html
  15. Jun 2025
  16. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    An optimised Bcl-3 inhibitor for melanoma treatment
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.17467
  17. www.sciencedirect.com www.sciencedirect.com
    Pyruvate kinase M2 (PKM2) tetramerization protects against hepatic stellate cell activation and liver fibrosis
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    sciencedirect.com/science/article/pii/S0002944020303722
  18. May 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12055001/
  20. Apr 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of β3 subunit of the GABA type A receptor in triple negative breast cancer proliferation, migration, and cell cycle progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11174043/
  22. Mar 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An in vivo screen identifies NAT10 as a master regulator of brain metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11939035/
  24. Jan 2025
  25. www.sciencedirect.com www.sciencedirect.com
    Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
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    sciencedirect.com/science/article/pii/S2451945624005166
  26. Nov 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11475318/
  28. Sep 2024
  29. link.springer.com link.springer.com
    TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus
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    link.springer.com/article/10.1007/s12035-024-04504-x
  30. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    UA influences the progression of breast cancer via the AhR/p27Kip1/cyclin E pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400938R
  31. www.sciencedirect.com www.sciencedirect.com
    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
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    sciencedirect.com/science/article/pii/S2211124724011136
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320024/
  34. Jul 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
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    ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293357/
  37. Jun 2024
  38. link.springer.com link.springer.com
    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
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    link.springer.com/article/10.1038/s41388-024-03081-6
  39. May 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
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    sciencedirect.com/science/article/pii/S1535610824001636
  41. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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    52.53.155.43/761c70660e3a03a822484173742c13c4c44cc6bf/PIIS2589004224010915-html.html
  42. Apr 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10996809/
  45. Mar 2024
  46. www.nature.com www.nature.com
    Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis
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    nature.com/articles/s41388-024-03008-1
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
  48. www.sciencedirect.com www.sciencedirect.com
    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
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    sciencedirect.com/science/article/pii/S2211124724002031
  49. Feb 2024
  50. www.sciencedirect.com www.sciencedirect.com
    Sphingolipid metabolism controls mammalian heart regeneration
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    sciencedirect.com/science/article/pii/S1550413124000172
  51. Jan 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Mechanism of GW117 antidepressant action: melatonin receptor-mediated regulation of sleep rhythm
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    sciencedirect.com/science/article/pii/S0014299923008130
  53. Dec 2023
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
  55. Nov 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
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    sciencedirect.com/science/article/pii/S2211124723014493
  57. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124723014201
  58. Aug 2023
  59. www.science.org www.science.org
    A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
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    science.org/doi/10.1126/scisignal.ade6737
  60. Jul 2023
  61. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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    sciencedirect.com/science/article/pii/S2666379123002483
  62. May 2023
  63. www.sciencedirect.com www.sciencedirect.com
    Modeling breast cancer proliferation, drug synergies, and alternating therapies
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    sciencedirect.com/science/article/pii/S2589004223007915
  64. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    sciencedirect.com/science/article/pii/S2211124722008750
  65. Feb 2023
  66. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC9887205/
  68. www.sciencedirect.com www.sciencedirect.com
    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
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    sciencedirect.com/science/article/pii/S1097276523000382
  69. Jan 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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    sciencedirect.com/science/article/pii/S2211124723000426
  71. Nov 2022
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular TMEM16A is necessary for myogenesis of skeletal muscle
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    ncbi.nlm.nih.gov/pmc/articles/PMC9647518/
  73. www.sciencedirect.com www.sciencedirect.com
    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    sciencedirect.com/science/article/pii/S2352396422004947
  74. Sep 2022
  75. www.sciencedirect.com www.sciencedirect.com
    TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3
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    sciencedirect.com/science/article/pii/S2211124722012529
  76. Aug 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    sciencedirect.com/science/article/pii/S2211124722009949
  78. Jul 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC9317664/
  80. www.sciencedirect.com www.sciencedirect.com
    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
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    sciencedirect.com/science/article/pii/S1550413122002303
  81. Mar 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch
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    sciencedirect.com/science/article/pii/S2211124722002017
  83. Dec 2021
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC8652204/
  86. Oct 2021
  87. mct.aacrjournals.org mct.aacrjournals.org
    Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
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    mct.aacrjournals.org/content/20/10/2049
  88. www.sciencedirect.com www.sciencedirect.com
    Proteome-wide mapping of short-lived proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276521007498
  89. Sep 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
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    sciencedirect.com/science/article/pii/S2211124721010822
  91. Aug 2021
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6483596/
  93. Jul 2021
  94. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15434
  95. link.springer.com link.springer.com
    RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
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    link.springer.com/article/10.1186/s40659-019-0268-x
  96. www.sciencedirect.com www.sciencedirect.com
    Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway
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    sciencedirect.com/science/article/pii/S0898656819302190
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6314484/
  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SARNP, a participant in mRNA splicing and export, negatively regulates E‐cadherin expression via interaction with pinin
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.29073
  99. Jun 2021
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
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    ncbi.nlm.nih.gov/pmc/articles/PMC8184503/
  101. May 2021
  102. www.sciencedirect.com www.sciencedirect.com
    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
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    sciencedirect.com/science/article/pii/S1534580721003993
  103. www.sciencedirect.com www.sciencedirect.com
    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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    sciencedirect.com/science/article/pii/S1097276520304238
  104. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1097276520302690
  105. Feb 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
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    sciencedirect.com/science/article/pii/S2211124721000620
  107. Jan 2021
  108. link.springer.com link.springer.com
    A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
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    link.springer.com/article/10.1007/s10637-020-01042-w
  109. Nov 2020
  110. link.springer.com link.springer.com
    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
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    link.springer.com/article/10.1007/s10571-020-01006-x
  111. Oct 2020
  112. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
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    sciencedirect.com/science/article/pii/S2211124720312730
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  114. Sep 2020
  115. www.sciencedirect.com www.sciencedirect.com
    Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
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    sciencedirect.com/science/article/pii/S2211124719317401
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
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    onlinelibrary.wiley.com/doi/10.1002/jcp.29743
  117. www.sciencedirect.com www.sciencedirect.com
    Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P
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    sciencedirect.com/science/article/pii/S2211124720310342
  118. www.sciencedirect.com www.sciencedirect.com
    Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
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    sciencedirect.com/science/article/pii/S2211124720305209
  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long noncoding RNA SOX2OT promotes the proliferation of pancreatic cancer by binding to FUS
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32827
  120. www.sciencedirect.com www.sciencedirect.com
    GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma
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    sciencedirect.com/science/article/pii/S2352396420303170
  121. Jan 2020
  122. www.sciencedirect.com www.sciencedirect.com
    Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
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    sciencedirect.com/science/article/pii/S2451945619303927
  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐487a‐3p functions as a new tumor suppressor in prostate cancer by targeting CCND1
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    onlinelibrary.wiley.com/doi/10.1002/jcp.29078
  124. academic.oup.com academic.oup.com
    Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures
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    academic.oup.com/endo/article/160/11/2600/5535649
  125. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2451945619301084
  126. www.sciencedirect.com www.sciencedirect.com
    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity
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    sciencedirect.com/science/article/pii/S2211124718317650
  127. elifesciences.org elifesciences.org
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    elifesciences.org/articles/40396
  128. www.sciencedirect.com www.sciencedirect.com
    De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma
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  129. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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  131. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate
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    PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis
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    NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis
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    Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
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    Canonical Wnt/β-Catenin Signaling Regulates Postnatal Mouse Epididymal Development But Does Not Affect Epithelial Cell Differentiation
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  136. Nov 2017
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    Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus - ScienceDirect
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    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
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    Maternal Low Protein Isocaloric Diet Suppresses Pancreatic β-Cell Proliferation in Mouse Offspring via miR-15b
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    The antiviral cytokine interferon‐gamma restricts neural stem/progenitor cell proliferation through activation of STAT1 and modulation of retinoblastoma protein phosphorylation
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