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  1. Last 7 days
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    ATG9B regulates bacterial internalization via actin rearrangement
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066431/
  3. Apr 2024
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    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
  5. Mar 2024
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    IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF
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    Astrocyte focal adhesion kinase reduces passive stress coping by inhibiting ciliary neurotrophic factor only in female mice
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    Substrate-bound and soluble domains of tenascin-C regulate differentiation, proliferation and migration of neural stem and progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902920/
  9. Feb 2024
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    Annexin A2 modulates phospholipid membrane composition upstream of Arp2 to control angiogenic sprout initiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10586062/
  11. Jan 2024
  12. 52.53.155.43 52.53.155.43
    Kisspeptin Regulates Cell Invasion and Migration in Endometrial Cancer
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    FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
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    1. scibot 10 Jan 2024
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  14. Dec 2023
  15. www.biorxiv.org www.biorxiv.org
    Together, Neuropilin 1 and Neuropilin 2 direct α5 integrin trafficking through GTPase-activating-protein p120RasGAP in endothelial cells to promote fibronectin fibrillogenesis
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    1. scibot 02 Dec 2023
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      DOI: 10.1101/2023.11.28.568967

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  16. Nov 2023
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    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
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    The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
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    1. scibot 02 Nov 2023
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      DOI: 10.7554/eLife.89141

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    ncbi.nlm.nih.gov/pmc/articles/PMC10615368/
  19. Oct 2023
  20. aiche.onlinelibrary.wiley.com aiche.onlinelibrary.wiley.com
    Mechanochemical coupling of MGF mediates periodontal regeneration
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    1. scibot 09 Oct 2023
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    aiche.onlinelibrary.wiley.com/doi/10.1002/btm2.10603
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    Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling
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  22. Sep 2023
  23. 52.53.155.43 52.53.155.43
    bvad117-html.html
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  24. Jul 2023
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    Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors
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    sciencedirect.com/science/article/pii/S2589004223013792
  26. Jun 2023
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    sciencedirect.com/science/article/pii/S1550413123001845
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    Macrophage-derived cathepsin S remodels the extracellular matrix to promote liver fibrogenesis
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    Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
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    sciencedirect.com/science/article/pii/S1097276523003325
  30. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610823001629
  32. Apr 2023
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    Cocaine and habit training cause dendritic spine rearrangement in the prelimbic cortex
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    sciencedirect.com/science/article/pii/S2589004223003176
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    Identification of a comprehensive alternative splicing function during epithelial-mesenchymal transition
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    sciencedirect.com/science/article/pii/S2589004223005941
  35. Mar 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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    Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
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    sciencedirect.com/science/article/pii/S2211124723001754
  39. Feb 2023
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    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    sciencedirect.com/science/article/pii/S1550413123000116
  41. Jan 2023
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    sciencedirect.com/science/article/pii/S1934590922004945
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    Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
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      DOI: 10.1158/1535-7163.MCT-21-0964

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    ncbi.nlm.nih.gov/pmc/articles/PMC9630827/
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    A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration
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    sciencedirect.com/science/article/pii/S1534580722008498
  45. Dec 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncogenic PI3K-induced transcriptomic landscape reveals key functions in splicing and gene expression regulation
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      DOI: 10.1158/0008-5472.CAN-22-0446

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    ncbi.nlm.nih.gov/pmc/articles/PMC9354703/
  47. Oct 2022
  48. www.nature.com www.nature.com
    Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy
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      DOI: 10.1038/s41418-022-01072-2

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    nature.com/articles/s41418-022-01072-2
  49. Sep 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    sciencedirect.com/science/article/pii/S2211124722011378
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    Exploring the target scope of KEAP1 E3 ligase-based PROTACs
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      DOI: 10.1016/j.chembiol.2022.08.003

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    sciencedirect.com/science/article/pii/S2451945622003117
  52. Aug 2022
  53. journals.plos.org journals.plos.org
    Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions
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      DOI: 10.1371/journal.pbio.3001759

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    journals.plos.org/plosbiology/article
  54. Jul 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610822002756
  56. May 2022
  57. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice
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      DOI: 10.14814/phy2.15301

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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15301
  58. Apr 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice
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    sciencedirect.com/science/article/pii/S2666379122001148
  60. Mar 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
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      DOI: 10.7554/eLife.68481

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    ncbi.nlm.nih.gov/pmc/articles/PMC8937232/
  62. Feb 2022
  63. www.sciencedirect.com www.sciencedirect.com
    LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland
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    Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
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    Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis
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  66. www.sciencedirect.com www.sciencedirect.com
    βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer
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  67. Jan 2022
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    GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries
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  70. Dec 2021
  71. link.springer.com link.springer.com
    PDIA3 inhibits mitochondrial respiratory function in brain endothelial cells and C. elegans through STAT3 signaling and decreases survival after OGD
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  72. Oct 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1
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    Biosensors based on peptide exposure show single molecule conformations in live cells
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  75. Sep 2021
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    Senescent immune cells release grancalcin to promote skeletal aging
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  77. Jul 2021
  78. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways
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    Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF
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    Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
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    Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts
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      Cell-signalling technology Cat. #3285

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  82. Jun 2021
  83. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
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    Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis
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  85. May 2021
  86. mcr.aacrjournals.org mcr.aacrjournals.org
    Adaptor protein ShcD/SHC4 interacts with Tie2 receptor to synergistically promote glioma cell invasion
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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  88. Apr 2021
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    CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
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  90. Mar 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Embryonic Stem-Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK
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    Paradoxical activation of c-Src as a drug-resistant mechanism
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    A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration
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  94. Feb 2021
  95. www.cell.com www.cell.com
    Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms
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  96. Dec 2020
  97. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function hot spot mutant p53R248Q regulation of integrin/FAK/ERK signaling in esophageal squamous cell carcinoma
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adaptation of endothelial cells to shear stress under atheroprone conditions by modulating internalization of vascular endothelial cadherin and vinculin
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  99. Sep 2020
  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of astrocyte FAK–JNK signaling promotes subventricular zone neurogenesis through CNTF
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling
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      DOI: 10.7554/eLife.57617

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  102. link.springer.com link.springer.com
    Targeting the Tie2–α v β 3 integrin axis with bi-specific reagents for the inhibition of angiogenesis
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      RRID:AB_10694068

      DOI: 10.1186/s12915-018-0557-9

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  103. Jan 2020
  104. jcs.biologists.org jcs.biologists.org
    Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin–FAK and uPAR signaling
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  105. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐ angiogenesis effects via targeting VEGFR‐2 signaling
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      DOI: 10.1111/bph.14813

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  106. www.sciencedirect.com www.sciencedirect.com
    Vitronectin mitigates stroke-increased neurogenesis only in female mice and through FAK-regulated IL-6
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    A Role of Agrin in Maintaining the Stability of Vascular Endothelial Growth Factor Receptor-2 during Tumor Angiogenesis
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    γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A
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    Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
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  111. Nov 2018
  112. academic.oup.com academic.oup.com
    Insulinlike Growth Factor–Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance
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  113. Nov 2017
  114. www.sciencedirect.com www.sciencedirect.com
    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
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