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May 2026
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5′-Triphosphate guanosine RNAs recruit GTP-binding proteins to suppress RIG-I/IFN type I signaling

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1. scibot 09 May 2026
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.molcel.2026.04.014
  
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sciencedirect.com/science/article/pii/S1097276526002686
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

ARAP2 regulates responses to interferon-gamma by restricting SOCS1

1
1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116667
  
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sciencedirect.com:5037/science/article/pii/S2211124725014391
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma

1
1. scibot 26 Nov 2025
  
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  DOI: 10.1158/2326-6066.CIR-25-0086
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12642826/
Sep 2025
journals.plos.org journals.plos.org

Microglial deficiency in the ATRX chromatin remodeler elicits a viral mimicry immune response that impacts neuronal function and behavior

1
1. scibot 16 Sep 2025
  
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  DOI: 10.1371/journal.pbio.3002659
  
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journals.plos.org/plosbiology/article
May 2025
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An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

1
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  DOI: 10.1016/j.celrep.2025.115728
  
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sciencedirect.com/science/article/pii/S2211124725004991
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Effective recognition of double-stranded RNA does not require activation of cellular inflammation

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  DOI: 10.1126/sciadv.ads6498
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980852/
Mar 2025
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The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene

1
1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115462
  
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sciencedirect.com/science/article/pii/S2211124725002335
Feb 2025
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Nucleic-acid-induced ZCCHC3 condensation promotes broad innate immune responses

1
1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.molcel.2025.01.027
  
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sciencedirect.com/science/article/pii/S1097276525000619
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E3 ligase SYVN1-mediated polyubiquitination of CPSF6 promotes alternative polyadenylation and antivirus effects of macrophages

1
1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115276
  
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sciencedirect.com/science/article/pii/S2211124725000476
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cholesterol restriction primes antiviral innate immunity via SREBP1-driven noncanonical type I IFNs

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1. scibot 30 Jan 2025
  
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  DOI: 10.1038/s44319-024-00346-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11772592/
Dec 2024
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RNA sensing induced by chromosome missegregation augments anti-tumor immunity

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.025
  
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sciencedirect.com/science/article/pii/S109727652400950X
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Pressure to evade cell-autonomous innate sensing reveals interplay between mitophagy, IFN signaling, and SARS-CoV-2 evolution

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115115
  
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sciencedirect.com/science/article/pii/S2211124724014669
Oct 2024
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Type I IFN drives unconventional IL-1β secretion in lupus monocytes

1
1. scibot 09 Oct 2024
  
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  AB_2269233
  
  DOI: 10.1016/j.immuni.2024.09.004
  
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sciencedirect.com/science/article/pii/S1074761324004485
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Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer

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1. scibot 09 Oct 2024
  
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  AB_2269233
  
  DOI: 10.1016/j.cell.2024.09.024
  
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sciencedirect.com/science/article/pii/S0092867424010729
Aug 2024
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An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation

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1. scibot 22 Aug 2024
  
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  AB_2269233
  
  DOI: 10.1016/j.celrep.2024.114618
  
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sciencedirect.com/science/article/pii/S2211124724009689
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The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response

1
1. scibot 20 Aug 2024
  
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  AB_2269233
  
  DOI: 10.1016/j.celrep.2024.114608
  
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sciencedirect.com/science/article/pii/S2211124724009586
www.nature.com www.nature.com

Table 1 Reagents table

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1. scibot 02 Aug 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1038/s41467-019-11250-5
  
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nature.com/articles/s41467-019-11250-5/tables/1
May 2024
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

1
1. scibot 21 May 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.cell.2024.04.025
  
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sciencedirect.com/science/article/pii/S0092867424004513
www.biorxiv.org www.biorxiv.org

Viral mimicry and memory deficits upon microglial deletion of ATRX

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1. scibot 16 May 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1101/2024.05.07.592875
  
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biorxiv.org/content/10.1101/2024.05.07.592875v1
Mar 2024
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Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation

1
1. scibot 15 Mar 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.celrep.2024.113945
  
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sciencedirect.com/science/article/pii/S2211124724002730
Feb 2024
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RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion

2
1. scibot 23 Feb 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1158/0008-5472.CAN-23-2049
  
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2. scibot 23 Feb 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1158/0008-5472.CAN-23-2049
  
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aacrjournals.org/cancerres/article/84/3/405/733849/RNA-Methyltransferase-FTSJ3-Regulates-the-Type-I
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Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells

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1. scibot 16 Feb 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.isci.2024.109068
  
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sciencedirect.com/science/article/pii/S258900422400289X
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gasdermin-D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway

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1. scibot 10 Jan 2024
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.isci.2023.108463
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10767184/
Nov 2023
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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

1
1. scibot 17 Nov 2023
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.celrep.2023.113352
  
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sciencedirect.com/science/article/pii/S2211124723013645
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility

1
1. scibot 26 Aug 2023
  
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  RRID:AB_2269233
  
  DOI: 10.1126/sciadv.adg5211
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10438455/
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XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility

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1. scibot 25 Aug 2023
  
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  DOI: 10.1126/sciadv.adg5211
  
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science.org/doi/10.1126/sciadv.adg5211
Jun 2023
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An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

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1. scibot 16 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.018
  
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sciencedirect.com/science/article/pii/S109727652300374X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization

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1. scibot 07 Jun 2023
  
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  DOI: 10.15698/mic2023.06.797
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10236204/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists

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1. scibot 06 Jan 2023
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.isci.2022.105742
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9726650/
Dec 2022
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A rapid RIG-I signaling relay mediates efficient antiviral response

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1. scibot 17 Dec 2022
  
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  DOI: 10.1016/j.molcel.2022.11.018
  
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sciencedirect.com/science/article/pii/S1097276522011315
Nov 2022
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 22 Nov 2022
  
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  RRID:AB_2269233
  
  DOI: 10.1002/1878-0261.13322
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13322
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AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity

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1. scibot 17 Nov 2022
  
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  DOI: 10.1016/j.molcel.2022.10.026
  
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sciencedirect.com/science/article/pii/S1097276522010541
Sep 2022
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SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

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1. scibot 24 Sep 2022
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.molcel.2022.08.031
  
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sciencedirect.com/science/article/pii/S1097276522008516
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

1
1. scibot 17 Jun 2022
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.isci.2022.104404
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9194172/
Mar 2022
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A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis

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1. scibot 27 Mar 2022
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.chembiol.2022.03.006
  
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Jan 2022
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Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription

1
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  RRID:AB_2269233
  
  DOI: 10.1016/j.celrep.2022.110302
  
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Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

1
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  DOI: 10.1016/j.molcel.2021.07.040
  
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Untitled document

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  DOI: 10.7554/eLife.24425
  
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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity

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  DOI: 10.1016/j.chom.2018.11.001
  
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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

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  RRID:AB_2269233
  
  DOI: 10.1016/j.ccell.2021.06.018
  
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Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity

1
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  DOI: 10.1016/j.molcel.2021.06.004
  
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DHX15 is required to control RNA virus-induced intestinal inflammation

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  RRID:AB_2269233
  
  DOI: 10.1016/j.celrep.2021.109205
  
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May 2021
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TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology

1
1. scibot 07 May 2021
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.molcel.2020.10.018
  
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Endogenous retrovirus expression activates type-I interferon signaling in an experimental mouse model of mesothelioma development

1
1. scibot 11 Mar 2021
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.canlet.2021.03.004
  
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Jan 2021
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The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling

1
1. scibot 20 Jan 2021
  
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  RRID:AB_2269233
  
  DOI: 10.1016/j.celrep.2020.108631
  
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ADAR1 Facilitates KSHV Lytic Reactivation by Modulating the RLR-Dependent Signaling Pathway

1
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  RRID:AB_2269233
  
  DOI: 10.1016/j.celrep.2020.107564
  
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Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres

1
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  DOI: 10.1016/j.celrep.2020.107983
  
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Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

1
1. scibot 16 Aug 2020
  
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  RRID:AB_226923
  
  DOI: 10.1016/j.celrep.2020.01.030
  
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Jan 2020
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Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS

1
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  RRID:AB_2269233
  
  DOI: 10.1016/j.cell.2019.05.003
  
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SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation

1
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  DOI: 10.1016/j.celrep.2019.06.027
  
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N6-Methyladenosine Modification Controls Circular RNA Immunity

1
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  RRID:AB_2269233
  
  DOI: 10.1016/j.molcel.2019.07.016
  
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Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages

1
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  RRID:AB_2269233
  
  DOI: 10.1016/j.chom.2018.10.008
  
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NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

1
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  RRID:AB_2269233
  
  DOI: 10.1016/j.chom.2019.02.013
  
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Untitled document

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  DOI: 10.1016/j.chom.2019.02.015
  
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Nov 2018
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Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

1
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Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

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Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

1
1. scibot 05 Nov 2018
  
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Nov 2017
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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

1
1. scibot 08 Nov 2017
  
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elifesciences.org elifesciences.org

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

1
1. scibot 08 Nov 2017
  
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  AB_2269233
  
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Sensing Self and Foreign Circular RNAs by Intron Identity

1
1. scibot 08 Nov 2017
  
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  AB_2269233
  
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