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Dual roles of AXIN1 as a β-catenin p-S60-dependent cytokinesis machinery and an ESCRT component

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1. scibot 17 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.117923
  
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sciencedirect.com/science/article/pii/S2589004226033067
Oct 2026
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A TMEM119-tankyrase axis restrains microglial phagocytosis to maintain memory and enables pharmacological forgetting

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1. scibot 01 Oct 2026
  
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  DOI: 10.1016/j.neuron.2026.09.001
  
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sciencedirect.com/science/article/pii/S0896627326006847
Jul 2026
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PUMILIO proteins maintain lineage balance via post-transcriptional repression of germline fate and promotion of somatic differentiation

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1. scibot 11 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117682
  
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sciencedirect.com/science/article/pii/S2211124726007606
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Panx1 deficiency exacerbates GAN diet-induced obesity by destabilizing β-catenin via GSK3β

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1. scibot 21 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115098
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12999355/
Jan 2026
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Wnt signaling inhibits casein kinase 1α activity by modulating its interaction with protein phosphatase 2A

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1. scibot 28 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.115274
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12829546/
Dec 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225027622-main-html.html

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.isci.2025.114501
  
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54.241.53.176/2b06d68b56fd35648bb8c883fa5f10d713483e37/1-s2.0-S2589004225027622-main-html.html
Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225021376-main-html.html

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113876
  
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54.241.53.176/1317e59fd2d0f056081cc0eecb18d40452c42a91/1-s2.0-S2589004225021376-main-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor

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1. scibot 28 May 2025
  
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  DOI: 10.1038/s41467-025-59984-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12095580/
Dec 2024
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
Jul 2024
www.embopress.org www.embopress.org

Non-canonical NF-κB signaling limits the tolerogenic β-catenin-Raldh2 axis in gut dendritic cells to exacerbate intestinal pathologies

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1. scibot 30 Jul 2024
  
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  DOI: 10.1038/s44318-024-00182-6
  
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embopress.org/doi/10.1038/s44318-024-00182-6
May 2024
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Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling

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1. scibot 04 May 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-2268
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
Jan 2024
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miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.

1
1. scibot 18 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108650
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
Dec 2023
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Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma

1
1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.ccell.2023.11.010
  
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sciencedirect.com/science/article/pii/S1535610823004014
Aug 2023
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USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase separation potential

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.chembiol.2023.07.016
  
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sciencedirect.com/science/article/abs/pii/S2451945623002465
Jul 2023
52.53.155.43 52.53.155.43

British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html

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1. scibot 21 Jul 2023
  
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  RRID:AB_2274550
  
  DOI: 10.1111/bph.16193
  
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52.53.155.43/51180316abfac9593501c4c683749a3ad6cad477/British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
Jun 2023
www.jneurosci.org www.jneurosci.org

A unique role for Protocadherin γC3 in promoting dendrite arborization through an Axin1-dependent mechanism

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1. scibot 01 Jun 2023
  
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  DOI: 10.1523/JNEUROSCI.0729-22.2022
  
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jneurosci.org/content/43/6/918
Jan 2023
www.nature.com www.nature.com

TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal

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1. scibot 05 Jan 2023
  
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  RRID:AB_2274550
  
  DOI: 10.1038/s41423-022-00963-1
  
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nature.com/articles/s41423-022-00963-1
Nov 2022
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RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

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1. scibot 10 Nov 2022
  
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  RRID:AB_2274550
  
  DOI: 10.1016/j.isci.2022.105184
  
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sciencedirect.com/science/article/pii/S2589004222014560
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiplexed protein profiling reveals spatial subcellular signaling networks

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1. scibot 21 Sep 2022
  
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  DOI: 10.1016/j.isci.2022.104980
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9460555/
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Tankyrase Inhibition Attenuates Cardiac Dilatation and Dysfunction in Ischemic Heart Failure

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1. scibot 07 Sep 2022
  
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  DOI: 10.3390/ijms231710059
  
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mdpi.com/1422-0067/23/17/10059
Apr 2022
aacrjournals.org aacrjournals.org

Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models

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1. scibot 27 Apr 2022
  
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  DOI: 10.1158/2767-9764.CRC-22-0027
  
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aacrjournals.org/cancerrescommun/article/2/4/233/694510/The-Tankyrase-Inhibitor-OM-153-Demonstrates
Mar 2022
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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

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1. scibot 23 Mar 2022
  
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  RRID:AB_2274550
  
  DOI: 10.1016/j.celrep.2022.110538
  
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sciencedirect.com/science/article/pii/S2211124722002790
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Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop

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1. scibot 05 Mar 2022
  
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  RRID:AB_2274550
  
  DOI: 10.1038/s41419-022-04607-0
  
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nature.com/articles/s41419-022-04607-0
Feb 2022
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An AMPKα2-specific phospho-switch controls lysosomal targeting for activation

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1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110365
  
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sciencedirect.com/science/article/pii/S2211124722000869
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells

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1. scibot 15 Jan 2022
  
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  DOI: 10.7554/eLife.64498
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8752093/
Nov 2021
cancerci.biomedcentral.com cancerci.biomedcentral.com

Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming

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1. scibot 09 Nov 2021
  
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  DOI: 10.1186/s12935-021-02303-1
  
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cancerci.biomedcentral.com/articles/10.1186/s12935-021-02303-1
Aug 2021
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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

1
1. scibot 07 Aug 2021
  
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  DOI: 10.1016/j.isci.2021.102807
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
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Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation

1
1. scibot 05 Aug 2021
  
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  DOI: 10.1016/j.molcel.2021.07.013
  
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sciencedirect.com/science/article/pii/S1097276521005827
Jul 2021
elifesciences.org elifesciences.org

Untitled document

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1. scibot 28 Jul 2021
  
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  DOI: 10.7554/eLife.42619
  
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elifesciences.org/articles/42619
May 2021
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A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.07.010
  
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sciencedirect.com/science/article/pii/S1534580720305840
Sep 2020
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Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108049
  
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sciencedirect.com/science/article/pii/S2211124720310342
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Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

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  DOI: 10.1016/j.cell.2020.03.006
  
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sciencedirect.com/science/article/pii/S0092867420302683
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GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107973
  
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sciencedirect.com/science/article/pii/S2211124720309542
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Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107922
  
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sciencedirect.com/science/article/pii/S2211124720309037
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  DOI: 10.7554/eLife.42619
  
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  RRID:AB_2274550 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2274550

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6398977/
Nov 2018
europepmc.org europepmc.org

A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3α and GSK3β in Regulating Embryonic Stem Cell Fate.

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2274550
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2087, RRID:AB_2274550)
  
  SciCrunch record: RRID:AB_2274550
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2274550 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2274550

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URL

europepmc.org/articles/PMC5851779/
Nov 2017
www.sciencedirect.com www.sciencedirect.com

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2274550
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2087, RRID:AB_2274550)
  
  SciCrunch record: RRID:AB_2274550
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2274550 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2274550

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scibot

URL

sciencedirect.com/science/article/pii/S1535610817301034